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343 related items for PubMed ID: 1697502

  • 21. In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.
    Spears CP, Shahinian AH, Moran RG, Heidelberger C, Corbett TH.
    Cancer Res; 1982 Feb; 42(2):450-6. PubMed ID: 6173112
    [Abstract] [Full Text] [Related]

  • 22. Modulation of 5-fluorouracil resistance in human colon tumor cell lines by azidothymidine.
    Findenig G, Mader RM, Fritzer-Szekeres M, Steger GG, Jaeger W, Szekeres T.
    Oncol Res; 1996 Feb; 8(5):189-96. PubMed ID: 8884811
    [Abstract] [Full Text] [Related]

  • 23. Biochemical mechanisms of interferon modulation of 5-fluorouracil activity in colon cancer cells.
    van der Wilt CL, Smid K, Aherne GW, Noordhuis P, Peters GJ.
    Eur J Cancer; 1997 Mar; 33(3):471-8. PubMed ID: 9155534
    [Abstract] [Full Text] [Related]

  • 24. Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.
    Jackman AL, Alison DL, Calvert AH, Harrap KR.
    Cancer Res; 1986 Jun; 46(6):2810-5. PubMed ID: 2938731
    [Abstract] [Full Text] [Related]

  • 25. Regrowth of 5-fluorouracil-treated human colon cancer cells is prevented by the combination of interferon gamma, indomethacin, and phenylbutyrate.
    Huang Y, Horvath CM, Waxman S.
    Cancer Res; 2000 Jun 15; 60(12):3200-6. PubMed ID: 10866311
    [Abstract] [Full Text] [Related]

  • 26. A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
    Emura T, Suzuki N, Yamaguchi M, Ohshimo H, Fukushima M.
    Int J Oncol; 2004 Sep 15; 25(3):571-8. PubMed ID: 15289858
    [Abstract] [Full Text] [Related]

  • 27. Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules.
    Aschele C, Sobrero A, Faderan MA, Bertino JR.
    Cancer Res; 1992 Apr 01; 52(7):1855-64. PubMed ID: 1532346
    [Abstract] [Full Text] [Related]

  • 28. Differential effects of recombinant interferon-alpha and 5-fluorouracil against colon cancer cells or against peripheral blood mononuclear cells.
    De Filippi R, Prete SP, Giuliani A, Silvi E, Yamaue H, Nieroda CA, Greiner JW, De Vecchis L, Bonmassar E.
    Anticancer Res; 1994 Apr 01; 14(5A):1767-73. PubMed ID: 7847809
    [Abstract] [Full Text] [Related]

  • 29. Enhancement of 5-fluoro-2'-deoxyuridine antineoplastic activity by 5-benzyloxybenzyloxybenzylacyclouridine in a human colon carcinoma cell line.
    Chu E, Chu MY, Darnowski JW, Chen ZH, Pan BC, Chu SH.
    Cancer Res; 1992 Apr 01; 52(7):1729-36. PubMed ID: 1532344
    [Abstract] [Full Text] [Related]

  • 30. Combined modulation by leucovorin and alpha-2a interferon of fluoropyrimidine mediated growth inhibition.
    Sinnige HA, Timmer-Bosscha H, Peters GF, De Vries EG, Mulder NH.
    Anticancer Res; 1993 Apr 01; 13(5A):1335-40. PubMed ID: 8239504
    [Abstract] [Full Text] [Related]

  • 31. Enhanced cytotoxicity with interleukin-1 alpha and 5-fluorouracil in HCT116 colon cancer cells.
    Geoffroy FJ, Allegra CJ, Sinha B, Grem JL.
    Oncol Res; 1994 Apr 01; 6(12):581-91. PubMed ID: 7787251
    [Abstract] [Full Text] [Related]

  • 32. Mechanisms underlying apoptosis induced by combination of 5-fluorouracil and interferon-gamma.
    Koshiji M, Adachi Y, Taketani S, Takeuchi K, Hioki K, Ikehara S.
    Biochem Biophys Res Commun; 1997 Nov 17; 240(2):376-81. PubMed ID: 9388485
    [Abstract] [Full Text] [Related]

  • 33. Mutation(s) of the thymidylate synthase gene of human adenocarcinoma cells causes a thymidylate synthase-negative phenotype that can be attenuated by exogenous folates.
    Houghton PJ, Rahman A, Will CL, Dolnick BJ, Houghton JA.
    Cancer Res; 1992 Feb 01; 52(3):558-65. PubMed ID: 1732043
    [Abstract] [Full Text] [Related]

  • 34. The effect of dose and interval between 5-fluorouracil and leucovorin on the formation of thymidylate synthase ternary complex in human cancer cells.
    Drake JC, Voeller DM, Allegra CJ, Johnston PG.
    Br J Cancer; 1995 Jun 01; 71(6):1145-50. PubMed ID: 7779703
    [Abstract] [Full Text] [Related]

  • 35. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
    Nita ME, Tominaga O, Nagawa H, Tsuruo T, Muto T.
    Hepatogastroenterology; 1998 Jun 01; 45(24):2117-22. PubMed ID: 9951876
    [Abstract] [Full Text] [Related]

  • 36. Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue.
    Johnston PG, Liang CM, Henry S, Chabner BA, Allegra CJ.
    Cancer Res; 1991 Dec 15; 51(24):6668-76. PubMed ID: 1720706
    [Abstract] [Full Text] [Related]

  • 37. The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates.
    Longley DB, Boyer J, Allen WL, Latif T, Ferguson PR, Maxwell PJ, McDermott U, Lynch M, Harkin DP, Johnston PG.
    Cancer Res; 2002 May 01; 62(9):2644-9. PubMed ID: 11980662
    [Abstract] [Full Text] [Related]

  • 38. Alteration of fluorouracil metabolism in human colon cancer cells by dipyridamole with a selective increase in fluorodeoxyuridine monophosphate levels.
    Grem JL, Fischer PH.
    Cancer Res; 1986 Dec 01; 46(12 Pt 1):6191-9. PubMed ID: 2946402
    [Abstract] [Full Text] [Related]

  • 39. Effect of the combined treatment with 5-fluorouracil, gamma-interferon or folinic acid on carcinoembryonic antigen expression in colon cancer cells.
    Aquino A, Prete SP, Greiner JW, Giuliani A, Graziani G, Turriziani M, De Filippi R, Masci G, Bonmassar E, De Vecchis L.
    Clin Cancer Res; 1998 Oct 01; 4(10):2473-81. PubMed ID: 9796980
    [Abstract] [Full Text] [Related]

  • 40. Role of thymidylate synthase in the antitumor activity of the multitargeted antifolate, LY231514.
    Schultz RM, Patel VF, Worzalla JF, Shih C.
    Anticancer Res; 1999 Oct 01; 19(1A):437-43. PubMed ID: 10226579
    [Abstract] [Full Text] [Related]

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