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73 related items for PubMed ID: 1698968

  • 1. Modulation of the picrotoxin receptor by fluorinated ethyl, methyl-butyrolactones.
    Yoon KW, Canney DJ, Covey DF, Rothman SM.
    J Pharmacol Exp Ther; 1990 Oct; 255(1):248-55. PubMed ID: 1698968
    [Abstract] [Full Text] [Related]

  • 2. Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist.
    Holland KD, Yoon KW, Ferrendelli JA, Covey DF, Rothman SM.
    Mol Pharmacol; 1991 Jan; 39(1):79-84. PubMed ID: 1846222
    [Abstract] [Full Text] [Related]

  • 3. Dual modulation of the gamma-aminobutyric acid type A receptor/ionophore by alkyl-substituted gamma-butyrolactones.
    Holland KD, Mathews GC, Bolos-Sy AM, Tucker JB, Reddy PA, Covey DF, Ferrendelli JA, Rothman SM.
    Mol Pharmacol; 1995 Jun; 47(6):1217-23. PubMed ID: 7603463
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function.
    Canney DJ, Lu HF, McKeon AC, Yoon KW, Xu K, Holland KD, Rothman SM, Ferrendelli JA, Covey DF.
    Bioorg Med Chem; 1998 Jan; 6(1):43-55. PubMed ID: 9502104
    [Abstract] [Full Text] [Related]

  • 5. The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study.
    Pistis M, Belelli D, Peters JA, Lambert JJ.
    Br J Pharmacol; 1997 Dec; 122(8):1707-19. PubMed ID: 9422818
    [Abstract] [Full Text] [Related]

  • 6. Binding interactions of convulsant and anticonvulsant gamma-butyrolactones and gamma-thiobutyrolactones with the picrotoxin receptor.
    Holland KD, McKeon AC, Covey DF, Ferrendelli JA.
    J Pharmacol Exp Ther; 1990 Aug; 254(2):578-83. PubMed ID: 2166797
    [Abstract] [Full Text] [Related]

  • 7. Physiological regulation of the picrotoxin receptor by gamma-butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons.
    Holland KD, Ferrendelli JA, Covey DF, Rothman SM.
    J Neurosci; 1990 Jun; 10(6):1719-27. PubMed ID: 2355246
    [Abstract] [Full Text] [Related]

  • 8. Voltage-dependent calcium channels as targets for convulsant and anticonvulsant alkyl-substituted thiobutyrolactones.
    Gross RA, Covey DF, Ferrendelli JA.
    J Pharmacol Exp Ther; 1997 Feb; 280(2):686-94. PubMed ID: 9023280
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of type A GABA receptors by L-type calcium channel blockers.
    Das P, Bell-Horner CL, Huang RQ, Raut A, Gonzales EB, Chen ZL, Covey DF, Dillon GH.
    Neuroscience; 2004 Feb; 124(1):195-206. PubMed ID: 14960351
    [Abstract] [Full Text] [Related]

  • 10. Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site.
    Williams KL, Tucker JB, White G, Weiss DS, Ferrendelli JA, Covey DF, Krause JE, Rothman SM.
    Mol Pharmacol; 1997 Jul; 52(1):114-9. PubMed ID: 9224820
    [Abstract] [Full Text] [Related]

  • 11. Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons.
    Yoon KW, Covey DF, Rothman SM.
    J Physiol; 1993 May; 464():423-39. PubMed ID: 8229811
    [Abstract] [Full Text] [Related]

  • 12. Physiological comparison of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors.
    Mathews GC, Bolos-Sy AM, Covey DF, Rothman SM, Ferrendelli JA.
    Neuropharmacology; 1996 Feb; 35(2):123-36. PubMed ID: 8734480
    [Abstract] [Full Text] [Related]

  • 13. Pharmacology of the human gamma-aminobutyric acidA receptor alpha 4 subunit expressed in Xenopus laevis oocytes.
    Whittemore ER, Yang W, Drewe JA, Woodward RM.
    Mol Pharmacol; 1996 Nov; 50(5):1364-75. PubMed ID: 8913369
    [Abstract] [Full Text] [Related]

  • 14. Pharmacological properties of GABAA receptors containing gamma1 subunits.
    Khom S, Baburin I, Timin EN, Hohaus A, Sieghart W, Hering S.
    Mol Pharmacol; 2006 Feb; 69(2):640-9. PubMed ID: 16272224
    [Abstract] [Full Text] [Related]

  • 15. U-93631 causes rapid decay of gamma-aminobutyric acid-induced chloride currents in recombinant rat gamma-aminobutyric acid type A receptors.
    Dillon GH, Im HK, Hamilton BJ, Carter DB, Gammill RB, Judge TM, Im WB.
    Mol Pharmacol; 1993 Oct; 44(4):860-5. PubMed ID: 8232235
    [Abstract] [Full Text] [Related]

  • 16. 6,2'-Dihydroxyflavone, a subtype-selective partial inverse agonist of GABAA receptor benzodiazepine site.
    Wang F, Xu Z, Yuen CT, Chow CY, Lui YL, Tsang SY, Xue H.
    Neuropharmacology; 2007 Sep; 53(4):574-82. PubMed ID: 17681556
    [Abstract] [Full Text] [Related]

  • 17. Anticonvulsant properties of alpha, gamma, and alpha, gamma-substituted gamma-butyrolactones.
    Klunk WE, Covey DF, Ferrendelli JA.
    Mol Pharmacol; 1982 Sep; 22(2):438-43. PubMed ID: 7144736
    [Abstract] [Full Text] [Related]

  • 18. Subunit-dependent block by isoflurane of wild-type and mutant alpha(1)S270H GABA(A) receptor currents in Xenopus oocytes.
    Hall AC, Stevens RJ, Betts BA, Yeung WY, Kelley JC, Harrison NL.
    Neurosci Lett; 2005 Jul 15; 382(3):332-7. PubMed ID: 15925114
    [Abstract] [Full Text] [Related]

  • 19. The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
    Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS.
    J Pharmacol Exp Ther; 2006 Dec 15; 319(3):1244-52. PubMed ID: 16971504
    [Abstract] [Full Text] [Related]

  • 20. Pentylenetetrazole-induced inhibition of recombinant gamma-aminobutyric acid type A (GABA(A)) receptors: mechanism and site of action.
    Huang RQ, Bell-Horner CL, Dibas MI, Covey DF, Drewe JA, Dillon GH.
    J Pharmacol Exp Ther; 2001 Sep 15; 298(3):986-95. PubMed ID: 11504794
    [Abstract] [Full Text] [Related]

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