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148 related items for PubMed ID: 16996686

  • 1. Hypoxia-induced upregulation of endothelial small G protein RhoA and Rho-kinase/ROCK2 inhibits eNOS expression.
    Jin HG, Yamashita H, Nagano Y, Fukuba H, Hiji M, Ohtsuki T, Takahashi T, Kohriyama T, Kaibuchi K, Matsumoto M.
    Neurosci Lett; 2006 Nov 06; 408(1):62-7. PubMed ID: 16996686
    [Abstract] [Full Text] [Related]

  • 2. Rho-kinase phosphorylates eNOS at threonine 495 in endothelial cells.
    Sugimoto M, Nakayama M, Goto TM, Amano M, Komori K, Kaibuchi K.
    Biochem Biophys Res Commun; 2007 Sep 21; 361(2):462-7. PubMed ID: 17651694
    [Abstract] [Full Text] [Related]

  • 3. Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase.
    Trebicka J, Hennenberg M, Laleman W, Shelest N, Biecker E, Schepke M, Nevens F, Sauerbruch T, Heller J.
    Hepatology; 2007 Jul 21; 46(1):242-53. PubMed ID: 17596891
    [Abstract] [Full Text] [Related]

  • 4. Citron Rho-interacting kinase mediates arsenite-induced decrease in endothelial nitric oxide synthase activity by increasing phosphorylation at threonine 497: Mechanism underlying arsenite-induced vascular dysfunction.
    Seo J, Cho DH, Lee HJ, Sung MS, Lee JY, Won KJ, Park JH, Jo I.
    Free Radic Biol Med; 2016 Jan 21; 90():133-44. PubMed ID: 26593676
    [Abstract] [Full Text] [Related]

  • 5. RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction.
    Bivalacqua TJ, Champion HC, Usta MF, Cellek S, Chitaley K, Webb RC, Lewis RL, Mills TM, Hellstrom WJ, Kadowitz PJ.
    Proc Natl Acad Sci U S A; 2004 Jun 15; 101(24):9121-6. PubMed ID: 15184671
    [Abstract] [Full Text] [Related]

  • 6. Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase.
    Takemoto M, Sun J, Hiroki J, Shimokawa H, Liao JK.
    Circulation; 2002 Jul 02; 106(1):57-62. PubMed ID: 12093770
    [Abstract] [Full Text] [Related]

  • 7. Endothelial nitric oxide synthase keeps erection regulatory function balance in the penis.
    Bivalacqua TJ, Liu T, Musicki B, Champion HC, Burnett AL.
    Eur Urol; 2007 Jun 02; 51(6):1732-40. PubMed ID: 17113219
    [Abstract] [Full Text] [Related]

  • 8. Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms.
    Shin HK, Salomone S, Potts EM, Lee SW, Millican E, Noma K, Huang PL, Boas DA, Liao JK, Moskowitz MA, Ayata C.
    J Cereb Blood Flow Metab; 2007 May 02; 27(5):998-1009. PubMed ID: 17033691
    [Abstract] [Full Text] [Related]

  • 9. Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells.
    Ming XF, Viswambharan H, Barandier C, Ruffieux J, Kaibuchi K, Rusconi S, Yang Z.
    Mol Cell Biol; 2002 Dec 02; 22(24):8467-77. PubMed ID: 12446767
    [Abstract] [Full Text] [Related]

  • 10. Integrin-linked kinase regulates endothelial cell nitric oxide synthase expression in hepatic sinusoidal endothelial cells.
    Shafiei MS, Lui S, Rockey DC.
    Liver Int; 2015 Apr 02; 35(4):1213-21. PubMed ID: 24906011
    [Abstract] [Full Text] [Related]

  • 11. PKC is required for activation of ROCK by RhoA in human endothelial cells.
    Barandier C, Ming XF, Rusconi S, Yang Z.
    Biochem Biophys Res Commun; 2003 May 16; 304(4):714-9. PubMed ID: 12727213
    [Abstract] [Full Text] [Related]

  • 12. Small GTPase RhoA and its effector rho kinase mediate oxygen glucose deprivation-evoked in vitro cerebral barrier dysfunction.
    Allen C, Srivastava K, Bayraktutan U.
    Stroke; 2010 Sep 16; 41(9):2056-63. PubMed ID: 20651275
    [Abstract] [Full Text] [Related]

  • 13. Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice.
    Abe K, Tawara S, Oi K, Hizume T, Uwatoku T, Fukumoto Y, Kaibuchi K, Shimokawa H.
    J Cardiovasc Pharmacol; 2006 Dec 16; 48(6):280-5. PubMed ID: 17204906
    [Abstract] [Full Text] [Related]

  • 14. Role of protease-activated receptor-1 in endothelial nitric oxide synthase-Thr495 phosphorylation.
    Watts VL, Motley ED.
    Exp Biol Med (Maywood); 2009 Feb 16; 234(2):132-9. PubMed ID: 19064940
    [Abstract] [Full Text] [Related]

  • 15. High salt medium activates RhoA/ROCK and downregulates eNOS expression via the upregulation of ADMA.
    Cao Y, Fang Y, Mu J, Liu X.
    Mol Med Rep; 2016 Jul 16; 14(1):606-12. PubMed ID: 27175806
    [Abstract] [Full Text] [Related]

  • 16. Sodium Ferulate Reduces Portal Pressure Through Inhibition of RhoA/Rho-Kinase and Activation of Endothelial Nitric Oxide Synthase in Cirrhotic Rats.
    Liu J, Peng L, Yang J, Wang M, Xu S, Liu J, Han P, He J, Tian D, Zhou Q.
    Dig Dis Sci; 2015 Jul 16; 60(7):2019-29. PubMed ID: 25724163
    [Abstract] [Full Text] [Related]

  • 17. Involvement of nuclear factor-kB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells.
    Shimizu S, Tahara M, Ogata S, Hashimoto K, Morishige K, Tasaka K, Murata Y.
    Mol Hum Reprod; 2007 Mar 16; 13(3):181-7. PubMed ID: 17227815
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of RhoA/Rho-kinase pathway suppresses the expression of type I collagen induced by TGF-beta2 in human retinal pigment epithelial cells.
    Itoh Y, Kimoto K, Imaizumi M, Nakatsuka K.
    Exp Eye Res; 2007 Mar 16; 84(3):464-72. PubMed ID: 17217948
    [Abstract] [Full Text] [Related]

  • 19. The role of the RhoA/Rho-kinase signaling pathway in renal vascular reactivity in endothelial nitric oxide synthase null mice.
    Williams J, Bogwu J, Oyekan A.
    J Hypertens; 2006 Jul 16; 24(7):1429-36. PubMed ID: 16794494
    [Abstract] [Full Text] [Related]

  • 20. Reconstituted high-density lipoprotein inhibits thrombin-induced endothelial tissue factor expression through inhibition of RhoA and stimulation of phosphatidylinositol 3-kinase but not Akt/endothelial nitric oxide synthase.
    Viswambharan H, Ming XF, Zhu S, Hubsch A, Lerch P, Vergères G, Rusconi S, Yang Z.
    Circ Res; 2004 Apr 16; 94(7):918-25. PubMed ID: 14988229
    [Abstract] [Full Text] [Related]


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