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Journal Abstract Search

190 related items for PubMed ID: 16997532

  • 1. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
    Sobol E, Yagen B, Lamb JG, White HS, Wlodarczyk BJ, Finnell RH, Bialer M.
    Epilepsy Res; 2007 Jan; 73(1):75-84. PubMed ID: 16997532
    [Abstract] [Full Text] [Related]

  • 2. Tetramethylcyclopropyl analogue of the leading antiepileptic drug, valproic acid: evaluation of the teratogenic effects of its amide derivatives in NMRI mice.
    Okada A, Onishi Y, Yagen B, Shimshoni JA, Kaufmann D, Bialer M, Fujiwara M.
    Birth Defects Res A Clin Mol Teratol; 2008 Sep; 82(9):610-21. PubMed ID: 18671279
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  • 3. Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.
    Okada A, Noyori H, Yagen B, Shimshoni JA, Bialer M, Fujiwara M.
    Birth Defects Res B Dev Reprod Toxicol; 2009 Oct; 86(5):394-401. PubMed ID: 19830722
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  • 4. Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid.
    Pessah N, Kaufmann D, Yagen B, Hen N, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsia; 2010 Oct; 51(10):1944-53. PubMed ID: 20738383
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  • 5. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
    Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsia; 2008 Jul; 49(7):1202-12. PubMed ID: 18435754
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  • 6. Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug.
    Isoherranen N, White HS, Finnell RH, Yagen B, Woodhead JH, Bennett GD, Wilcox KS, Barton ME, Bialer M.
    Epilepsia; 2002 Feb; 43(2):115-26. PubMed ID: 11903457
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  • 7. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
    Shimshoni JA, Yagen B, Wlodarczyk B, Finnell RH, Schurig V, Bialer M.
    Epilepsia; 2010 Mar; 51(3):323-32. PubMed ID: 19674061
    [Abstract] [Full Text] [Related]

  • 8. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
    Pessah N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2009 Apr 23; 52(8):2233-42. PubMed ID: 19296679
    [Abstract] [Full Text] [Related]

  • 9. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.
    Sobol E, Yagen B, Steve White H, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M.
    Neuropharmacology; 2006 Sep 23; 51(4):933-46. PubMed ID: 16890251
    [Abstract] [Full Text] [Related]

  • 10. Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.
    Sobol E, Bialer M, Yagen B.
    J Med Chem; 2004 Aug 12; 47(17):4316-26. PubMed ID: 15294003
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  • 14. Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue.
    Shekh-Ahmad T, Bialer M, Yavin E.
    Epilepsy Res; 2012 Feb 12; 98(2-3):238-46. PubMed ID: 22057163
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  • 15. Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.
    Pessah N, Yagen B, Hen N, Shimshoni JA, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsy Behav; 2011 Nov 12; 22(3):461-8. PubMed ID: 21959082
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  • 16. Teratogenicity of valproate conjugates with anticonvulsant activity in mice.
    Spiegelstein O, Chatterjie N, Alexander G, Finnell RH.
    Epilepsy Res; 2003 Dec 12; 57(2-3):145-52. PubMed ID: 15013055
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  • 18. Myo-inositol enhances teratogenicity of valproic acid in the mouse.
    Massa V, Wlodarczyk B, Giavini E, Finnell RH.
    Birth Defects Res A Clin Mol Teratol; 2006 Mar 12; 76(3):200-4. PubMed ID: 16511884
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