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124 related items for PubMed ID: 16998901

  • 1. Lack of neprilysin suffices to generate murine amyloid-like deposits in the brain and behavioral deficit in vivo.
    Madani R, Poirier R, Wolfer DP, Welzl H, Groscurth P, Lipp HP, Lu B, El Mouedden M, Mercken M, Nitsch RM, Mohajeri MH.
    J Neurosci Res; 2006 Dec; 84(8):1871-8. PubMed ID: 16998901
    [Abstract] [Full Text] [Related]

  • 2. Neuronal neprilysin overexpression is associated with attenuation of Abeta-related spatial memory deficit.
    Poirier R, Wolfer DP, Welzl H, Tracy J, Galsworthy MJ, Nitsch RM, Mohajeri MH.
    Neurobiol Dis; 2006 Dec; 24(3):475-83. PubMed ID: 17008108
    [Abstract] [Full Text] [Related]

  • 3. Intraneuronal amyloid beta and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease.
    Van Broeck B, Vanhoutte G, Pirici D, Van Dam D, Wils H, Cuijt I, Vennekens K, Zabielski M, Michalik A, Theuns J, De Deyn PP, Van der Linden A, Van Broeckhoven C, Kumar-Singh S.
    Neurobiol Aging; 2008 Feb; 29(2):241-52. PubMed ID: 17112635
    [Abstract] [Full Text] [Related]

  • 4. Metabolic regulation of brain Abeta by neprilysin.
    Iwata N, Tsubuki S, Takaki Y, Shirotani K, Lu B, Gerard NP, Gerard C, Hama E, Lee HJ, Saido TC.
    Science; 2001 May 25; 292(5521):1550-2. PubMed ID: 11375493
    [Abstract] [Full Text] [Related]

  • 5. Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice.
    Knobloch M, Konietzko U, Krebs DC, Nitsch RM.
    Neurobiol Aging; 2007 Sep 25; 28(9):1297-306. PubMed ID: 16876915
    [Abstract] [Full Text] [Related]

  • 6. Effect of Tong Luo Jiu Nao on Aβ-degrading enzymes in AD rat brains.
    Liu Y, Hua Q, Lei H, Li P.
    J Ethnopharmacol; 2011 Sep 02; 137(2):1035-46. PubMed ID: 21798326
    [Abstract] [Full Text] [Related]

  • 7. Herpes simplex virus RNAi and neprilysin gene transfer vectors reduce accumulation of Alzheimer's disease-related amyloid-beta peptide in vivo.
    Hong CS, Goins WF, Goss JR, Burton EA, Glorioso JC.
    Gene Ther; 2006 Jul 02; 13(14):1068-79. PubMed ID: 16541122
    [Abstract] [Full Text] [Related]

  • 8. Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning.
    Senechal Y, Kelly PH, Dev KK.
    Behav Brain Res; 2008 Jan 10; 186(1):126-32. PubMed ID: 17884188
    [Abstract] [Full Text] [Related]

  • 9. Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation.
    Crouch PJ, Tew DJ, Du T, Nguyen DN, Caragounis A, Filiz G, Blake RE, Trounce IA, Soon CP, Laughton K, Perez KA, Li QX, Cherny RA, Masters CL, Barnham KJ, White AR.
    J Neurochem; 2009 Mar 10; 108(5):1198-207. PubMed ID: 19141082
    [Abstract] [Full Text] [Related]

  • 10. Synaptic transmission is impaired prior to plaque formation in amyloid precursor protein-overexpressing mice without altering behaviorally-correlated sharp wave-ripple complexes.
    Hermann D, Both M, Ebert U, Gross G, Schoemaker H, Draguhn A, Wicke K, Nimmrich V.
    Neuroscience; 2009 Sep 15; 162(4):1081-90. PubMed ID: 19477243
    [Abstract] [Full Text] [Related]

  • 11. Altered expression of Abeta metabolism-associated molecules from D-galactose/AlCl(3) induced mouse brain.
    Luo Y, Niu F, Sun Z, Cao W, Zhang X, Guan D, Lv Z, Zhang B, Xu Y.
    Mech Ageing Dev; 2009 Apr 15; 130(4):248-52. PubMed ID: 19150622
    [Abstract] [Full Text] [Related]

  • 12. High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain.
    Güntert A, Döbeli H, Bohrmann B.
    Neuroscience; 2006 Dec 01; 143(2):461-75. PubMed ID: 17008022
    [Abstract] [Full Text] [Related]

  • 13. Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders.
    Caccamo A, Oddo S, Sugarman MC, Akbari Y, LaFerla FM.
    Neurobiol Aging; 2005 May 01; 26(5):645-54. PubMed ID: 15708439
    [Abstract] [Full Text] [Related]

  • 14. Vaccination of Alzheimer's model mice with adenovirus vector containing quadrivalent foldable Abeta(1-15) reduces Abeta burden and behavioral impairment without Abeta-specific T cell response.
    Zou J, Yao Z, Zhang G, Wang H, Xu J, Yew DT, Forster EL.
    J Neurol Sci; 2008 Sep 15; 272(1-2):87-98. PubMed ID: 18571202
    [Abstract] [Full Text] [Related]

  • 15. Genetic deletion or antagonism of kinin B(1) and B(2) receptors improves cognitive deficits in a mouse model of Alzheimer's disease.
    Prediger RD, Medeiros R, Pandolfo P, Duarte FS, Passos GF, Pesquero JB, Campos MM, Calixto JB, Takahashi RN.
    Neuroscience; 2008 Feb 06; 151(3):631-43. PubMed ID: 18191900
    [Abstract] [Full Text] [Related]

  • 16. Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response.
    Prediger RD, Franco JL, Pandolfo P, Medeiros R, Duarte FS, Di Giunta G, Figueiredo CP, Farina M, Calixto JB, Takahashi RN, Dafre AL.
    Behav Brain Res; 2007 Feb 27; 177(2):205-13. PubMed ID: 17194489
    [Abstract] [Full Text] [Related]

  • 17. Chronic psychosocial stress exacerbates impairment of cognition and long-term potentiation in beta-amyloid rat model of Alzheimer's disease.
    Srivareerat M, Tran TT, Alzoubi KH, Alkadhi KA.
    Biol Psychiatry; 2009 Jun 01; 65(11):918-26. PubMed ID: 18849021
    [Abstract] [Full Text] [Related]

  • 18. Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.
    Iwata N, Takaki Y, Fukami S, Tsubuki S, Saido TC.
    J Neurosci Res; 2002 Nov 01; 70(3):493-500. PubMed ID: 12391610
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of amyloid-beta peptide and Alzheimer's disease.
    Iwata N, Higuchi M, Saido TC.
    Pharmacol Ther; 2005 Nov 01; 108(2):129-48. PubMed ID: 16112736
    [Abstract] [Full Text] [Related]

  • 20. Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: a role for intraneuronal amyloid.
    Giménez-Llort L, Blázquez G, Cañete T, Johansson B, Oddo S, Tobeña A, LaFerla FM, Fernández-Teruel A.
    Neurosci Biobehav Rev; 2007 Nov 01; 31(1):125-47. PubMed ID: 17055579
    [Abstract] [Full Text] [Related]

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