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235 related items for PubMed ID: 17010577

  • 1. LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance.
    Barancík M, Bohácová V, Sedlák J, Sulová Z, Breier A.
    Eur J Pharm Sci; 2006 Dec; 29(5):426-34. PubMed ID: 17010577
    [Abstract] [Full Text] [Related]

  • 2. Combined treatment of P-gp-positive L1210/VCR cells by verapamil and all-trans retinoic acid induces down-regulation of P-glycoprotein expression and transport activity.
    Sulová Z, Macejová D, Seres M, Sedlák J, Brtko J, Breier A.
    Toxicol In Vitro; 2008 Feb; 22(1):96-105. PubMed ID: 17920233
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine.
    Xie X, Tang B, Zhou J, Gao Q, Zhang P.
    Oncol Rep; 2013 Aug; 30(2):773-82. PubMed ID: 23743572
    [Abstract] [Full Text] [Related]

  • 4. Multidrug resistant P-glycoprotein positive L1210/VCR cells are also cross-resistant to cisplatin via a mechanism distinct from P-glycoprotein-mediated drug efflux activity.
    Gibalová L, Sedlák J, Labudová M, Barancík M, Reháková A, Breier A, Sulová Z.
    Gen Physiol Biophys; 2009 Dec; 28(4):391-403. PubMed ID: 20097962
    [Abstract] [Full Text] [Related]

  • 5. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR.
    Tang XQ, Bi H, Feng JQ, Cao JG.
    Acta Pharmacol Sin; 2005 Aug; 26(8):1009-16. PubMed ID: 16038636
    [Abstract] [Full Text] [Related]

  • 6. SB203580, a specific inhibitor of p38-MAPK pathway, is a new reversal agent of P-glycoprotein-mediated multidrug resistance.
    Barancík M, Bohácová V, Kvackajová J, Hudecová S, Krizanová O, Breier A.
    Eur J Pharm Sci; 2001 Aug; 14(1):29-36. PubMed ID: 11457647
    [Abstract] [Full Text] [Related]

  • 7. Reversal effect of PI3-K inhibitor LY294002 on P-glycoprotein-mediated multidrug resistance of human leukemia cell line K562/DNR and gastric cancer cell line SGC7901/ADR.
    Zhang Y, Qu XJ, Liu YP, Yang XH, Hou KZ, Teng YE, Zhang JD.
    Ai Zheng; 2009 Feb; 28(2):97-9. PubMed ID: 19550116
    [Abstract] [Full Text] [Related]

  • 8. P-glycoprotein depresses cisplatin sensitivity in L1210 cells by inhibiting cisplatin-induced caspase-3 activation.
    Gibalová L, Sereš M, Rusnák A, Ditte P, Labudová M, Uhrík B, Pastorek J, Sedlák J, Breier A, Sulová Z.
    Toxicol In Vitro; 2012 Apr; 26(3):435-44. PubMed ID: 22269388
    [Abstract] [Full Text] [Related]

  • 9. Potentiation of anticancer drugs: effects of pentoxifylline on neoplastic cells.
    Barancik M, Bohacova V, Gibalova L, Sedlak J, Sulova Z, Breier A.
    Int J Mol Sci; 2012 Apr; 13(1):369-82. PubMed ID: 22312258
    [Abstract] [Full Text] [Related]

  • 10. Cytotoxic activity of several unrelated drugs on L1210 mouse leukemic cell sublines with P-glycoprotein (PGP) mediated multidrug resistance (MDR) phenotype. A QSAR study.
    Breier A, Drobná Z, Docolomansky P, Barancik M.
    Neoplasma; 2000 Apr; 47(2):100-6. PubMed ID: 10985475
    [Abstract] [Full Text] [Related]

  • 11. Hyaluronan oligosaccharides sensitize lymphoma resistant cell lines to vincristine by modulating P-glycoprotein activity and PI3K/Akt pathway.
    Cordo Russo RI, García MG, Alaniz L, Blanco G, Alvarez E, Hajos SE.
    Int J Cancer; 2008 Mar 01; 122(5):1012-8. PubMed ID: 17985348
    [Abstract] [Full Text] [Related]

  • 12. beta(2)-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein.
    Wu CH, Rastegar M, Gordon J, Safa AR.
    Oncogene; 2001 Oct 25; 20(48):7006-20. PubMed ID: 11704825
    [Abstract] [Full Text] [Related]

  • 13. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C, Rahmani M, Dai Y, Conrad D, Krystal G, Dent P, Grant S.
    Cancer Res; 2003 Apr 15; 63(8):1822-33. PubMed ID: 12702569
    [Abstract] [Full Text] [Related]

  • 14. Time dependence of [3H]-vincristine accumulation by L1210 mouse leukemic cells. Effect of P-glycoprotein overexpression.
    Breier A, Stefanková Z, Barancík M, Tribulová N.
    Gen Physiol Biophys; 1994 Aug 15; 13(4):287-98. PubMed ID: 7890145
    [Abstract] [Full Text] [Related]

  • 15. Direct interaction between verapamil and doxorubicin causes the lack of reversal effect of verapamil on P-glycoprotein mediated resistance to doxorubicin in vitro using L1210/VCR cells.
    Breier A, Drobná Z, Barancík M.
    Neoplasma; 1998 Aug 15; 45(4):248-53. PubMed ID: 9890669
    [Abstract] [Full Text] [Related]

  • 16. Effect of pentoxifylline on P-glycoprotein mediated vincristine resistance of L1210 mouse leukemic cell line.
    Breier A, Barancík M, Stefanková Z, Uhrík B, Tribulová N.
    Neoplasma; 1994 Aug 15; 41(5):297-303. PubMed ID: 7854500
    [Abstract] [Full Text] [Related]

  • 17. L1210 cells cultivated under the selection pressure of doxorubicin or vincristine express common mechanisms of multidrug resistance based on the overexpression of P-glycoprotein.
    Bohácová V, Sulová Z, Dovinová I, Poláková E, Barancík M, Uhrík B, Orlický J, Breier A.
    Toxicol In Vitro; 2006 Dec 15; 20(8):1560-8. PubMed ID: 16962737
    [Abstract] [Full Text] [Related]

  • 18. Phosphatidylinositol 3-kinases inhibitor LY294002 potentiates the cytotoxic effects of doxorubicin, vincristine, and etoposide in a panel of cancer cell lines.
    Badinloo M, Esmaeili-Mahani S.
    Fundam Clin Pharmacol; 2014 Aug 15; 28(4):414-22. PubMed ID: 23837575
    [Abstract] [Full Text] [Related]

  • 19. DJ-1 is involved in the multidrug resistance of SGC7901 gastric cancer cells through PTEN/PI3K/Akt/Nrf2 pathway.
    Qiu L, Ma Z, Li X, Deng Y, Duan G, Zhao LE, Xu X, Xiao L, Liu H, Zhu Z, Chen H.
    Acta Biochim Biophys Sin (Shanghai); 2020 Dec 11; 52(11):1202-1214. PubMed ID: 33079995
    [Abstract] [Full Text] [Related]

  • 20. Apoptosis induction of human leukemia cells by Streptomyces sp. SY-103 metabolites through activation of caspase-3 and inactivation of Akt.
    Jeong SY, Han MH, Jin CY, Kim GY, Choi BT, Nam TJ, Kim SK, Choi YH.
    Int J Mol Med; 2010 Jan 11; 25(1):31-40. PubMed ID: 19956899
    [Abstract] [Full Text] [Related]

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