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Journal Abstract Search

213 related items for PubMed ID: 17015640

  • 1. Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis.
    Vidal C, Gómez-Hernández A, Sánchez-Galán E, González A, Ortega L, Gómez-Gerique JA, Tuñón J, Egido J.
    J Pharmacol Exp Ther; 2007 Jan; 320(1):108-16. PubMed ID: 17015640
    [Abstract] [Full Text] [Related]

  • 2. The lipoxygenase-cyclooxygenase inhibitor licofelone prevents thromboxane A2-mediated cardiovascular derangement triggered by the inflammatory peptide fMLP in the rabbit.
    Rotondo S, Dell'Elba G, Manarini S, Cerletti C, Evangelista V.
    Eur J Pharmacol; 2006 Sep 28; 546(1-3):95-101. PubMed ID: 16920097
    [Abstract] [Full Text] [Related]

  • 3. Licofelone--clinical update on a novel LOX/COX inhibitor for the treatment of osteoarthritis.
    Alvaro-Gracia JM.
    Rheumatology (Oxford); 2004 Feb 28; 43 Suppl 1():i21-5. PubMed ID: 14752172
    [Abstract] [Full Text] [Related]

  • 4. Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation.
    Rotondo S, Krauze-Brzósko K, Manarini S, Evangelista V, Cerletti C.
    Eur J Pharmacol; 2004 Mar 19; 488(1-3):79-83. PubMed ID: 15044038
    [Abstract] [Full Text] [Related]

  • 5. Licofelone, a novel 5-LOX/COX-inhibitor, attenuates leukocyte rolling and adhesion on endothelium under flow.
    Ulbrich H, Soehnlein O, Xie X, Eriksson EE, Lindbom L, Albrecht W, Laufer S, Dannhardt G.
    Biochem Pharmacol; 2005 Jul 01; 70(1):30-6. PubMed ID: 15894291
    [Abstract] [Full Text] [Related]

  • 6. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation.
    Kirchner T, Argentieri DC, Barbone AG, Singer M, Steber M, Ansell J, Beers SA, Wachter MP, Wu W, Malloy E, Stewart A, Ritchie DM.
    J Pharmacol Exp Ther; 1997 Aug 01; 282(2):1094-101. PubMed ID: 9262379
    [Abstract] [Full Text] [Related]

  • 7. The gastrointestinal tolerability of the LOX/COX inhibitor, licofelone, is similar to placebo and superior to naproxen therapy in healthy volunteers: results from a randomized, controlled trial.
    Bias P, Buchner A, Klesser B, Laufer S.
    Am J Gastroenterol; 2004 Apr 01; 99(4):611-8. PubMed ID: 15089890
    [Abstract] [Full Text] [Related]

  • 8. Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
    Tavolari S, Bonafè M, Marini M, Ferreri C, Bartolini G, Brighenti E, Manara S, Tomasi V, Laufer S, Guarnieri T.
    Carcinogenesis; 2008 Feb 01; 29(2):371-80. PubMed ID: 18033773
    [Abstract] [Full Text] [Related]

  • 9. Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids.
    Martel-Pelletier J, Mineau F, Fahmi H, Laufer S, Reboul P, Boileau C, Lavigne M, Pelletier JP.
    Arthritis Rheum; 2004 Dec 01; 50(12):3925-33. PubMed ID: 15593193
    [Abstract] [Full Text] [Related]

  • 10. Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition.
    Paredes Y, Massicotte F, Pelletier JP, Martel-Pelletier J, Laufer S, Lajeunesse D.
    Arthritis Rheum; 2002 Jul 01; 46(7):1804-12. PubMed ID: 12124864
    [Abstract] [Full Text] [Related]

  • 11. Superiority of the gastroduodenal safety profile of licofelone over rofecoxib, a COX-2 selective inhibitor, in dogs.
    Moreau M, Daminet S, Martel-Pelletier J, Fernandes J, Pelletier JP.
    J Vet Pharmacol Ther; 2005 Feb 01; 28(1):81-6. PubMed ID: 15720519
    [Abstract] [Full Text] [Related]

  • 12. Effects on primary haemostasis of an anti-inflammatory agent with 5-lipoxygenase and cyclooxygenase inhibitory activity.
    Hernandez MR, Tonda R, Pedreño J, Salas E, Arderiu G, Pino M, Serradell M, Escolar G.
    J Cardiovasc Med (Hagerstown); 2006 Dec 01; 7(12):859-65. PubMed ID: 17122671
    [Abstract] [Full Text] [Related]

  • 13. Anti-atherogenic effect of BHB-TZD having inhibitory activities on cyclooxygenase and 5-lipoxygenase in hyperlipidemic mice.
    Choi JH, Jeon HJ, Park JG, Sonn SK, Lee MR, Lee MN, You HJ, Kim GY, Kim JH, Lee MH, Kwon OS, Nam KH, Kim HC, Jeong TS, Lee WS, Oh GT.
    Atherosclerosis; 2010 Sep 01; 212(1):146-52. PubMed ID: 20684827
    [Abstract] [Full Text] [Related]

  • 14. Chronic arthritis aggravates vascular lesions in rabbits with atherosclerosis: a novel model of atherosclerosis associated with chronic inflammation.
    Largo R, Sánchez-Pernaute O, Marcos ME, Moreno-Rubio J, Aparicio C, Granado R, Ortega L, Egido J, Herrero-Beaumont G.
    Arthritis Rheum; 2008 Sep 01; 58(9):2723-34. PubMed ID: 18759289
    [Abstract] [Full Text] [Related]

  • 15. Atorvastatin reduces plaque vulnerability in an atherosclerotic rabbit model by altering the 5-lipoxygenase pathway.
    Zhou G, Ge S, Liu D, Xu G, Zhang R, Yin Q, Zhu W, Chen J, Liu X.
    Cardiology; 2010 Sep 01; 115(3):221-8. PubMed ID: 20234134
    [Abstract] [Full Text] [Related]

  • 16. Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke.
    Ye YN, Wu WK, Shin VY, Bruce IC, Wong BC, Cho CH.
    Carcinogenesis; 2005 Apr 01; 26(4):827-34. PubMed ID: 15637091
    [Abstract] [Full Text] [Related]

  • 17. Anticancer effects of licofelone (ML-3000) in prostate cancer cells.
    Narayanan NK, Nargi D, Attur M, Abramson SB, Narayanan BA.
    Anticancer Res; 2007 Apr 01; 27(4B):2393-402. PubMed ID: 17695530
    [Abstract] [Full Text] [Related]

  • 18. Licofelone inhibits interleukin-18-induced pro-inflammatory cytokine release and cellular proliferation in human mesangial cells.
    Wu YJ, Xue M, Chen H.
    Basic Clin Pharmacol Toxicol; 2012 Sep 01; 111(3):166-72. PubMed ID: 22433003
    [Abstract] [Full Text] [Related]

  • 19. The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway.
    Boileau C, Pelletier JP, Tardif G, Fahmi H, Laufer S, Lavigne M, Martel-Pelletier J.
    Ann Rheum Dis; 2005 Jun 01; 64(6):891-8. PubMed ID: 15498796
    [Abstract] [Full Text] [Related]

  • 20. Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.
    Fiorucci S, Distrutti E, Mencarelli A, Morelli A, Laufor SA, Cirino G, Wallace JL.
    Br J Pharmacol; 2003 Aug 01; 139(7):1351-9. PubMed ID: 12890715
    [Abstract] [Full Text] [Related]

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