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Journal Abstract Search

231 related items for PubMed ID: 17017804

  • 1. Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfone.
    Padayatti PS, Sheri A, Totir MA, Helfand MS, Carey MP, Anderson VE, Carey PR, Bethel CR, Bonomo RA, Buynak JD, van den Akker F.
    J Am Chem Soc; 2006 Oct 11; 128(40):13235-42. PubMed ID: 17017804
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  • 2. Penam sulfones and β-lactamase inhibition: SA2-13 and the importance of the C2 side chain length and composition.
    Rodkey EA, Winkler ML, Bethel CR, Pagadala SR, Buynak JD, Bonomo RA, van den Akker F.
    PLoS One; 2014 Oct 11; 9(1):e85892. PubMed ID: 24454944
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  • 3. Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.
    Helfand MS, Taracila MA, Totir MA, Bonomo RA, Buynak JD, van den Akker F, Carey PR.
    Biochemistry; 2007 Jul 24; 46(29):8689-99. PubMed ID: 17595114
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  • 4. Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure.
    Padayatti PS, Helfand MS, Totir MA, Carey MP, Hujer AM, Carey PR, Bonomo RA, van den Akker F.
    Biochemistry; 2004 Feb 03; 43(4):843-8. PubMed ID: 14744126
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  • 7. Different intermediate populations formed by tazobactam, sulbactam, and clavulanate reacting with SHV-1 beta-lactamases: Raman crystallographic evidence.
    Kalp M, Totir MA, Buynak JD, Carey PR.
    J Am Chem Soc; 2009 Feb 18; 131(6):2338-47. PubMed ID: 19161282
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  • 8. Effect of the inhibitor-resistant M69V substitution on the structures and populations of trans-enamine beta-lactamase intermediates.
    Totir MA, Padayatti PS, Helfand MS, Carey MP, Bonomo RA, Carey PR, van den Akker F.
    Biochemistry; 2006 Oct 03; 45(39):11895-904. PubMed ID: 17002290
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  • 9. The importance of the trans-enamine intermediate as a β-lactamase inhibition strategy probed in inhibitor-resistant SHV β-lactamase variants.
    Ke W, Rodkey EA, Sampson JM, Skalweit MJ, Sheri A, Pagadala SR, Nottingham MD, Buynak JD, Bonomo RA, van den Akker F.
    ChemMedChem; 2012 Jun 03; 7(6):1002-8. PubMed ID: 22438274
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  • 10. Following the reactions of mechanism-based inhibitors with beta-lactamase by Raman crystallography.
    Helfand MS, Totir MA, Carey MP, Hujer AM, Bonomo RA, Carey PR.
    Biochemistry; 2003 Nov 25; 42(46):13386-92. PubMed ID: 14621983
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  • 11. Crystal structures of the molecular class A β-lactamase TEM-171 and its complexes with tazobactam.
    Grigorenko VG, Petrova TE, Carolan C, Rubtsova MY, Uporov IV, Pereira J, Chojnowski G, Samygina VR, Lamzin VS, Egorov AM.
    Acta Crystallogr D Struct Biol; 2022 Jul 01; 78(Pt 7):825-834. PubMed ID: 35775982
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  • 12. Studies on penam sulfones. I. Synthesis and beta-lactamase inhibitory activity of 2 beta-alkoxycarbonyl penicillanic acid sulfones.
    Setti EL, Reddy NA, Phillips OA, Czajkowski DP, Atchison K, Atwal H, Micetich RG, Maiti SN, Kunugita C, Hyodo A.
    J Antibiot (Tokyo); 1996 Sep 01; 49(9):944-6. PubMed ID: 8931732
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  • 13. Allyl and propargyl substituted penam sulfones as versatile intermediates toward the syntheses of new beta-lactamase inhibitors.
    Sandanayaka VP, Feigelson GB, Prashad AS, Yang Y, Petersen PJ.
    Bioorg Med Chem Lett; 2001 Apr 23; 11(8):997-1000. PubMed ID: 11327608
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  • 14. Tazobactam inactivation of SHV-1 and the inhibitor-resistant Ser130 -->Gly SHV-1 beta-lactamase: insights into the mechanism of inhibition.
    Pagan-Rodriguez D, Zhou X, Simmons R, Bethel CR, Hujer AM, Helfand MS, Jin Z, Guo B, Anderson VE, Ng LM, Bonomo RA.
    J Biol Chem; 2004 May 07; 279(19):19494-501. PubMed ID: 14757767
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