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Journal Abstract Search

296 related items for PubMed ID: 17017916

  • 1. Structural modelling of the human drug-metabolizing cytochromes P450.
    Lewis DF, Ito Y, Goldfarb PS.
    Curr Med Chem; 2006; 13(22):2645-52. PubMed ID: 17017916
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  • 2. Insights into drug metabolism by cytochromes P450 from modelling studies of CYP2D6-drug interactions.
    Maréchal JD, Kemp CA, Roberts GC, Paine MJ, Wolf CR, Sutcliffe MJ.
    Br J Pharmacol; 2008 Mar; 153 Suppl 1(Suppl 1):S82-9. PubMed ID: 18026129
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  • 3. The 2002 Bernard B. Brodie Award lecture: deciphering substrate recognition by drug-metabolizing cytochromes P450.
    Johnson EF.
    Drug Metab Dispos; 2003 Dec; 31(12):1532-40. PubMed ID: 14625350
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  • 6. Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity.
    Lewis DF, Ito Y.
    Xenobiotica; 2009 Aug; 39(8):625-35. PubMed ID: 19514836
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  • 7. Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling.
    Dong D, Wu B, Chow D, Hu M.
    Drug Metab Rev; 2012 May; 44(2):192-208. PubMed ID: 22251142
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  • 8. Flexibility of human cytochromes P450: molecular dynamics reveals differences between CYPs 3A4, 2C9, and 2A6, which correlate with their substrate preferences.
    Skopalík J, Anzenbacher P, Otyepka M.
    J Phys Chem B; 2008 Jul 10; 112(27):8165-73. PubMed ID: 18598011
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  • 12. Use of density functional theory in drug metabolism studies.
    Rydberg P, Jørgensen FS, Olsen L.
    Expert Opin Drug Metab Toxicol; 2014 Feb 10; 10(2):215-27. PubMed ID: 24295134
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  • 13. Human P450s in the metabolism of drugs: molecular modelling of enzyme-substrate interactions.
    Lewis DF.
    Expert Opin Drug Metab Toxicol; 2005 Jun 10; 1(1):5-8. PubMed ID: 16922648
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  • 15. Human drug metabolism and the cytochromes P450: application and relevance of in vitro models.
    Venkatakrishnan K, Von Moltke LL, Greenblatt DJ.
    J Clin Pharmacol; 2001 Nov 10; 41(11):1149-79. PubMed ID: 11697750
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  • 17. Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism.
    Isvoran A, Louet M, Vladoiu DL, Craciun D, Loriot MA, Villoutreix BO, Miteva MA.
    Drug Discov Today; 2017 Feb 10; 22(2):366-376. PubMed ID: 27693711
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  • 18. Insights into drug metabolism from modelling studies of cytochrome P450-drug interactions.
    Maréchal JD, Sutcliffe MJ.
    Curr Top Med Chem; 2006 Feb 10; 6(15):1619-26. PubMed ID: 16918473
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