These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

212 related items for PubMed ID: 17020279

  • 1. Phenylalanine 445 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences C-Ring cyclization and deprotonation reactions.
    Wu TK, Liu YT, Chiu FH, Chang CH.
    Org Lett; 2006 Oct 12; 8(21):4691-4. PubMed ID: 17020279
    [Abstract] [Full Text] [Related]

  • 2. Tryptophan 232 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences rearrangement and deprotonation but not cyclization reactions.
    Wu TK, Yu MT, Liu YT, Chang CH, Wang HJ, Diau EW.
    Org Lett; 2006 Mar 30; 8(7):1319-22. PubMed ID: 16562881
    [Abstract] [Full Text] [Related]

  • 3. Alteration of the substrate's prefolded conformation and cyclization stereochemistry of oxidosqualene-lanosterol cyclase of Saccharomyces cerevisiae by substitution at phenylalanine 699.
    Wu TK, Chang CH, Wen HY, Liu YT, Li WH, Wang TT, Shie WS.
    Org Lett; 2010 Feb 05; 12(3):500-3. PubMed ID: 20055456
    [Abstract] [Full Text] [Related]

  • 4. Histidine residue at position 234 of oxidosqualene-lanosterol cyclase from saccharomyces cerevisiae simultaneously influences cyclization, rearrangement, and deprotonation reactions.
    Wu TK, Liu YT, Chang CH.
    Chembiochem; 2005 Jul 05; 6(7):1177-81. PubMed ID: 15915534
    [No Abstract] [Full Text] [Related]

  • 5.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 6.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 7. Mutation of isoleucine 705 of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae affects lanosterol's C/D-ring cyclization and 17α/β-exocyclic side chain stereochemistry.
    Wu TK, Chang YC, Liu YT, Chang CH, Wen HY, Li WH, Shie WS.
    Org Biomol Chem; 2011 Feb 21; 9(4):1092-7. PubMed ID: 21157613
    [Abstract] [Full Text] [Related]

  • 8. Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase: a chemistry-biology interdisciplinary study of the protein's structure-function-reaction mechanism relationships.
    Wu TK, Chang CH, Liu YT, Wang TT.
    Chem Rec; 2008 Feb 21; 8(5):302-25. PubMed ID: 18956480
    [Abstract] [Full Text] [Related]

  • 9. Importance of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase tyrosine 707 residue for chair-boat bicyclic ring formation and deprotonation reactions.
    Wu TK, Wang TT, Chang CH, Liu YT, Shie WS.
    Org Lett; 2008 Nov 06; 10(21):4959-62. PubMed ID: 18842050
    [Abstract] [Full Text] [Related]

  • 10. Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies.
    Oliaro-Bosso S, Schulz-Gasch T, Taramino S, Scaldaferri M, Viola F, Balliano G.
    Biochem Soc Trans; 2005 Nov 06; 33(Pt 5):1202-5. PubMed ID: 16246081
    [Abstract] [Full Text] [Related]

  • 11. Mechanistic insights into oxidosqualene cyclizations through homology modeling.
    Schulz-Gasch T, Stahl M.
    J Comput Chem; 2003 Apr 30; 24(6):741-53. PubMed ID: 12666166
    [Abstract] [Full Text] [Related]

  • 12. Steric bulk at position 454 in Saccharomyces cerevisiae lanosterol synthase influences B-ring formation but not deprotonation.
    Joubert BM, Hua L, Matsuda SP.
    Org Lett; 2000 Feb 10; 2(3):339-41. PubMed ID: 10814317
    [Abstract] [Full Text] [Related]

  • 13. The cysteine 703 to isoleucine or histidine mutation of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae generates an iridal-type triterpenoid.
    Chang CH, Chen YC, Tseng SW, Liu YT, Wen HY, Li WH, Huang CY, Ko CY, Wang TT, Wu TK.
    Biochimie; 2012 Nov 10; 94(11):2376-81. PubMed ID: 22732192
    [Abstract] [Full Text] [Related]

  • 14. Oxidosqualene cyclase second-sphere residues profoundly influence the product profile.
    Lodeiro S, Segura MJ, Stahl M, Schulz-Gasch T, Matsuda SP.
    Chembiochem; 2004 Nov 05; 5(11):1581-5. PubMed ID: 15515077
    [No Abstract] [Full Text] [Related]

  • 15. Directed evolution experiments reveal mutations at cycloartenol synthase residue His477 that dramatically alter catalysis.
    Segura MJ, Lodeiro S, Meyer MM, Patel AJ, Matsuda SP.
    Org Lett; 2002 Dec 12; 4(25):4459-62. PubMed ID: 12465912
    [Abstract] [Full Text] [Related]

  • 16. Protein engineering of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase into parkeol synthase.
    Liu YT, Hu TC, Chang CH, Shie WS, Wu TK.
    Org Lett; 2012 Oct 19; 14(20):5222-5. PubMed ID: 23043506
    [Abstract] [Full Text] [Related]

  • 17. Protein engineering of oxidosqualene-lanosterol cyclase into triterpene monocyclase.
    Chang CH, Wen HY, Shie WS, Lu CT, Li ME, Liu YT, Li WH, Wu TK.
    Org Biomol Chem; 2013 Jul 07; 11(25):4214-9. PubMed ID: 23680980
    [Abstract] [Full Text] [Related]

  • 18. Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase.
    Thoma R, Schulz-Gasch T, D'Arcy B, Benz J, Aebi J, Dehmlow H, Hennig M, Stihle M, Ruf A.
    Nature; 2004 Nov 04; 432(7013):118-22. PubMed ID: 15525992
    [Abstract] [Full Text] [Related]

  • 19. Enzymatic formation of multiple triterpenes by mutation of tyrosine 510 of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae.
    Wu TK, Chang CH.
    Chembiochem; 2004 Dec 03; 5(12):1712-5. PubMed ID: 15508118
    [No Abstract] [Full Text] [Related]

  • 20. Catalytic mechanism and product specificity of oxidosqualene-lanosterol cyclase: a QM/MM study.
    Tian BX, Eriksson LA.
    J Phys Chem B; 2012 Nov 29; 116(47):13857-62. PubMed ID: 23130825
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 11.