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Journal Abstract Search


122 related items for PubMed ID: 17021260

  • 1. Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice.
    Damaj MI, Siu EC, Sellers EM, Tyndale RF, Martin BR.
    J Pharmacol Exp Ther; 2007 Jan; 320(1):250-7. PubMed ID: 17021260
    [Abstract] [Full Text] [Related]

  • 2. Pharmacokinetic and pharmacodynamics studies of nicotine after oral administration in mice: effects of methoxsalen, a CYP2A5/6 inhibitor.
    Alsharari SD, Siu EC, Tyndale RF, Damaj MI.
    Nicotine Tob Res; 2014 Jan; 16(1):18-25. PubMed ID: 23884323
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of cytochrome P450 2A6 increases nicotine's oral bioavailability and decreases smoking.
    Sellers EM, Kaplan HL, Tyndale RF.
    Clin Pharmacol Ther; 2000 Jul; 68(1):35-43. PubMed ID: 10945314
    [Abstract] [Full Text] [Related]

  • 4. Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro.
    Zhang W, Kilicarslan T, Tyndale RF, Sellers EM.
    Drug Metab Dispos; 2001 Jun; 29(6):897-902. PubMed ID: 11353760
    [Abstract] [Full Text] [Related]

  • 5. Nicotine metabolism and urinary elimination in mouse: in vitro and in vivo.
    Raunio H, Pokela N, Puhakainen K, Rahnasto M, Mauriala T, Auriola S, Juvonen RO.
    Xenobiotica; 2008 Jan; 38(1):34-47. PubMed ID: 18098062
    [Abstract] [Full Text] [Related]

  • 6. Different modes of inhibition of mouse Cyp2a5 and rat CYP2A3 by the food-derived 8-methoxypsoralen.
    Visoni S, Meireles N, Monteiro L, Rossini A, Pinto LF.
    Food Chem Toxicol; 2008 Mar; 46(3):1190-5. PubMed ID: 18215451
    [Abstract] [Full Text] [Related]

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  • 8. The effect of methoxsalen on nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism in vivo.
    Sellers EM, Ramamoorthy Y, Zeman MV, Djordjevic MV, Tyndale RF.
    Nicotine Tob Res; 2003 Dec; 5(6):891-9. PubMed ID: 14668073
    [Abstract] [Full Text] [Related]

  • 9. Characterization and comparison of nicotine and cotinine metabolism in vitro and in vivo in DBA/2 and C57BL/6 mice.
    Siu EC, Tyndale RF.
    Mol Pharmacol; 2007 Mar; 71(3):826-34. PubMed ID: 17158199
    [Abstract] [Full Text] [Related]

  • 10. Selegiline is a mechanism-based inactivator of CYP2A6 inhibiting nicotine metabolism in humans and mice.
    Siu EC, Tyndale RF.
    J Pharmacol Exp Ther; 2008 Mar; 324(3):992-9. PubMed ID: 18065502
    [Abstract] [Full Text] [Related]

  • 11. Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance.
    Hukkanen J, Jacob P, Benowitz NL.
    Clin Pharmacol Ther; 2006 Nov; 80(5):522-30. PubMed ID: 17112808
    [Abstract] [Full Text] [Related]

  • 12. Single-dose methoxsalen effects on human cytochrome P-450 2A6 activity.
    Kharasch ED, Hankins DC, Taraday JK.
    Drug Metab Dispos; 2000 Jan; 28(1):28-33. PubMed ID: 10611136
    [Abstract] [Full Text] [Related]

  • 13. Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse.
    Li L, Jia K, Zhou X, McCallum SE, Hough LB, Ding X.
    J Pharmacol Exp Ther; 2013 Dec; 347(3):746-54. PubMed ID: 24045421
    [Abstract] [Full Text] [Related]

  • 14. Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.
    Takeuchi H, Saoo K, Yokohira M, Ikeda M, Maeta H, Miyazaki M, Yamazaki H, Kamataki T, Imaida K.
    Cancer Res; 2003 Nov 15; 63(22):7581-3. PubMed ID: 14633670
    [Abstract] [Full Text] [Related]

  • 15. Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.
    Rahnasto M, Raunio H, Poso A, Wittekindt C, Juvonen RO.
    J Med Chem; 2005 Jan 27; 48(2):440-9. PubMed ID: 15658857
    [Abstract] [Full Text] [Related]

  • 16. Nicotine self-administration in mice is associated with rates of nicotine inactivation by CYP2A5.
    Siu EC, Wildenauer DB, Tyndale RF.
    Psychopharmacology (Berl); 2006 Mar 27; 184(3-4):401-8. PubMed ID: 16485141
    [Abstract] [Full Text] [Related]

  • 17. Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model.
    Zhou X, Zhuo X, Xie F, Kluetzman K, Shu YZ, Humphreys WG, Ding X.
    J Pharmacol Exp Ther; 2010 Feb 27; 332(2):578-87. PubMed ID: 19923441
    [Abstract] [Full Text] [Related]

  • 18. Role of human cytochrome P4502A6 in C-oxidation of nicotine.
    Nakajima M, Yamamoto T, Nunoya K, Yokoi T, Nagashima K, Inoue K, Funae Y, Shimada N, Kamataki T, Kuroiwa Y.
    Drug Metab Dispos; 1996 Nov 27; 24(11):1212-7. PubMed ID: 8937855
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of coumarin 7-hydroxylase activity in human liver microsomes.
    Draper AJ, Madan A, Parkinson A.
    Arch Biochem Biophys; 1997 May 01; 341(1):47-61. PubMed ID: 9143352
    [Abstract] [Full Text] [Related]

  • 20. Inhibitory effects of neurotransmitters and steroids on human CYP2A6.
    Higashi E, Nakajima M, Katoh M, Tokudome S, Yokoi T.
    Drug Metab Dispos; 2007 Apr 01; 35(4):508-14. PubMed ID: 17237153
    [Abstract] [Full Text] [Related]


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