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146 related items for PubMed ID: 1702630

  • 1. 9-Beta-D-arabinofuranosyladenine 5'-monophosphate (araAMP) is converted directly to its antivirally active 5'-triphosphate form by 5-phosphoribosyl-1-pyrophosphate (PRPP) synthetase.
    Balzarini J, De Clercq E.
    Biochem Biophys Res Commun; 1990 Dec 31; 173(3):781-7. PubMed ID: 1702630
    [Abstract] [Full Text] [Related]

  • 2. Enzymatic phosphorylation and pyrophosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key metabolite in the pathway for activation of the anti-HIV (human immunodeficiency virus) agent 2',3'-dideoxyinosine.
    Navé JF, Eschbach A, Wolff-Kugel D, Halazy S, Balzarini J.
    Biochem Pharmacol; 1994 Sep 15; 48(6):1105-12. PubMed ID: 7945403
    [Abstract] [Full Text] [Related]

  • 3. 5-Phosphoribosyl 1-pyrophosphate synthetase converts the acyclic nucleoside phosphonates 9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 9-(2-phosphonylmethoxyethyl)adenine directly to their antivirally active diphosphate derivatives.
    Balzarini J, De Clercq E.
    J Biol Chem; 1991 May 15; 266(14):8686-9. PubMed ID: 1851154
    [Abstract] [Full Text] [Related]

  • 4. The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs.
    Cherney MM, Cherney LT, Garen CR, James MN.
    J Mol Biol; 2011 Nov 04; 413(4):844-56. PubMed ID: 21963988
    [Abstract] [Full Text] [Related]

  • 5. Pharmacodynamics and proposed mechanism of therapeutic action and host toxicity of 9-beta-D-arabinofuranosyl-2-fluoroadenine monophosphate (F-araAMP) in P388 murine leukemia-bearing mice.
    Avramis VI.
    Cancer Invest; 1989 Nov 04; 7(2):129-37. PubMed ID: 2477118
    [Abstract] [Full Text] [Related]

  • 6. Increased 5-phospho-alpha-D-ribose-1-diphosphate synthetase (ribosephosphate pyrophosphokinase, EC 2.7.6.1) activity in rat hepatomas.
    Baló-Banga JM, Weber G.
    Cancer Res; 1984 Nov 04; 44(11):5004-9. PubMed ID: 6091867
    [Abstract] [Full Text] [Related]

  • 7. Conversion of acyclic nucleoside phosphonates to their diphosphate derivatives by 5-phosphoribosyl-1-pyrophosphate (PRPP) synthetase.
    Balzarini J, De Clercq E.
    Adv Exp Med Biol; 1991 Nov 04; 309A():29-32. PubMed ID: 1665008
    [No Abstract] [Full Text] [Related]

  • 8. Purine biosynthesis de novo in bovine retina: purification and characterization of amidophosphoribosyl transferase and phosphoribosyl pyrophosphate synthetase.
    Kian IA, Etingof RN.
    Biochemistry (Mosc); 1999 Jun 04; 64(6):648-51. PubMed ID: 10395979
    [Abstract] [Full Text] [Related]

  • 9. Regulation of energy metabolism in macrophages during hypoxia. Roles of fructose 2,6-bisphosphate and ribose 1,5-bisphosphate.
    Kawaguchi T, Veech RL, Uyeda K.
    J Biol Chem; 2001 Jul 27; 276(30):28554-61. PubMed ID: 11373280
    [Abstract] [Full Text] [Related]

  • 10. The utilization of nucleotides by animal cells.
    Cohen SS, Plunkett W.
    Ann N Y Acad Sci; 1975 Aug 08; 255():269-86. PubMed ID: 1059361
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of 5-phosphoribosyl-1-pyrophosphate synthetase by the monophosphate metabolite of 4-amino-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine: a novel mechanism for antitumor activity.
    Fry DW, Boritzki TJ, Jackson RC, Cook PD, Leopold WR.
    Mol Pharmacol; 1993 Aug 08; 44(2):479-85. PubMed ID: 7689145
    [Abstract] [Full Text] [Related]

  • 12. Decreased erythrocyte phosphoribosylpyrophosphate synthetase activity and impaired formation in thalassemia minor: a mechanism for decreased adenine nucleotide content.
    Zerez CR, Lachant NA, Tanaka KR.
    J Lab Clin Med; 1989 Jul 08; 114(1):43-50. PubMed ID: 2544652
    [Abstract] [Full Text] [Related]

  • 13. Disposition of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-phosphate in mice and dogs.
    Noker PE, Duncan GF, El Dareer SM, Hill DL.
    Cancer Treat Rep; 1983 May 08; 67(5):445-56. PubMed ID: 6189605
    [Abstract] [Full Text] [Related]

  • 14. Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase.
    Alderwick LJ, Lloyd GS, Lloyd AJ, Lovering AL, Eggeling L, Besra GS.
    Glycobiology; 2011 Apr 08; 21(4):410-25. PubMed ID: 21045009
    [Abstract] [Full Text] [Related]

  • 15. [Increased activity of PRPP synthetase].
    Iizasa T.
    Nihon Rinsho; 2008 Apr 08; 66(4):694-8. PubMed ID: 18409517
    [Abstract] [Full Text] [Related]

  • 16. Penetration of mouse fibroblasts by the 5'-phosphate of 9-beta-D-arabinofuranosyladenine and incorporation of the nucleotide into DNA.
    Plunkett W, Lapi L, Ortiz PJ, Cohen SS.
    Proc Natl Acad Sci U S A; 1974 Jan 08; 71(1):73-7. PubMed ID: 4359332
    [Abstract] [Full Text] [Related]

  • 17. [Purine metabolism: determination of PRPP-amidotransferase and PRPP-synthetase in lymphocytes from patients with chronic lymphatic leukemia (CLL)].
    Tabucchi A, Terzuoli L, Di Stefano A, Pizzichini M, Leoncini R, Dispensa E, Marinello E.
    Boll Soc Ital Biol Sper; 1989 Nov 08; 65(11):1097-103. PubMed ID: 2560926
    [Abstract] [Full Text] [Related]

  • 18. Phosphoribosyl pyrophosphate synthetase activity affects growth and riboflavin production in Ashbya gossypii.
    Jiménez A, Santos MA, Revuelta JL.
    BMC Biotechnol; 2008 Sep 09; 8():67. PubMed ID: 18782443
    [Abstract] [Full Text] [Related]

  • 19. Ribose metabolism and nucleic acid synthesis in normal and glucose-6-phosphate dehydrogenase-deficient human erythrocytes infected with Plasmodium falciparum.
    Roth EF, Ruprecht RM, Schulman S, Vanderberg J, Olson JA.
    J Clin Invest; 1986 Apr 09; 77(4):1129-35. PubMed ID: 2420826
    [Abstract] [Full Text] [Related]

  • 20. Gout with superactive phosphoribosylpyrophosphate synthetase due to increased enzyme catalytic rate.
    Becker MA, Losman MJ, Itkin P, Simkin PA.
    J Lab Clin Med; 1982 Apr 09; 99(4):495-511. PubMed ID: 6174658
    [Abstract] [Full Text] [Related]

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