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Journal Abstract Search

187 related items for PubMed ID: 17034131

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  • 6. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
    Flinspach ML, Li H, Jamal J, Yang W, Huang H, Hah JM, Gómez-Vidal JA, Litzinger EA, Silverman RB, Poulos TL.
    Nat Struct Mol Biol; 2004 Jan; 11(1):54-9. PubMed ID: 14718923
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  • 7. Synthesis and evaluation of dipeptide amides containing N omega-nitroarginine and D-2,4-diaminobutyric acids as inhibitors of neuronal nitric oxide synthase.
    Huang H, Martásek P, Roman LJ, Silverman RB.
    J Enzyme Inhib; 2001 Jan; 16(3):233-9. PubMed ID: 11697043
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  • 8. Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Hah JM, Roman LJ, Martásek P, Silverman RB.
    J Med Chem; 2001 Aug 02; 44(16):2667-70. PubMed ID: 11472219
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  • 9. Hydroxyethylene isosteres of selective neuronal nitric oxide synthase inhibitors.
    Erdal EP, Martásek P, Roman LJ, Silverman RB.
    Bioorg Med Chem; 2007 Sep 15; 15(18):6096-108. PubMed ID: 17614291
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  • 10. Synthesis and evaluation of peptidomimetics as selective inhibitors and active site probes of nitric oxide synthases.
    Huang H, Martásek P, Roman LJ, Silverman RB.
    J Med Chem; 2000 Jul 27; 43(15):2938-45. PubMed ID: 10956202
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  • 11. Insights into the structural determinants for selective inhibition of nitric oxide synthase isoforms.
    Oliveira BL, Moreira IS, Fernandes PA, Ramos MJ, Santos I, Correia JD.
    J Mol Model; 2013 Apr 27; 19(4):1537-51. PubMed ID: 23263357
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  • 12. Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.
    Cinelli MA, Li H, Pensa AV, Kang S, Roman LJ, Martásek P, Poulos TL, Silverman RB.
    J Med Chem; 2015 Nov 12; 58(21):8694-712. PubMed ID: 26469213
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  • 13. Chiral linkers to improve selectivity of double-headed neuronal nitric oxide synthase inhibitors.
    Jing Q, Li H, Chreifi G, Roman LJ, Martásek P, Poulos TL, Silverman RB.
    Bioorg Med Chem Lett; 2013 Oct 15; 23(20):5674-9. PubMed ID: 23993333
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  • 14. Discovery of a series of aminopiperidines as novel iNOS inhibitors.
    Le Bourdonnec B, Leister LK, Ajello CA, Cassel JA, Seida PR, O'Hare H, Gu M, Chu GH, Tuthill PA, DeHaven RN, Dolle RE.
    Bioorg Med Chem Lett; 2008 Jan 01; 18(1):336-43. PubMed ID: 18024030
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  • 15. Synthesis and evaluation of trans 3,4-cyclopropyl L-arginine analogues as isoform selective inhibitors of nitric oxide synthase.
    Fishlock D, Perdicakis B, Montgomery HJ, Guillemette JG, Jervis E, Lajoie GA.
    Bioorg Med Chem; 2003 Mar 20; 11(6):869-73. PubMed ID: 12614872
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  • 16. Exploring the binding conformations of bulkier dipeptide amide inhibitors in constitutive nitric oxide synthases.
    Li H, Flinspach ML, Igarashi J, Jamal J, Yang W, Gómez-Vidal JA, Litzinger EA, Huang H, Erdal EP, Silverman RB, Poulos TL.
    Biochemistry; 2005 Nov 22; 44(46):15222-9. PubMed ID: 16285725
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  • 17. Development of urea and thiourea kynurenamine derivatives: synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors.
    Chayah M, Carrión MD, Gallo MA, Jiménez R, Duarte J, Camacho ME.
    ChemMedChem; 2015 May 22; 10(5):874-82. PubMed ID: 25801086
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  • 18. Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
    Flinspach M, Li H, Jamal J, Yang W, Huang H, Silverman RB, Poulos TL.
    Biochemistry; 2004 May 11; 43(18):5181-7. PubMed ID: 15122883
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  • 19. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.
    Pensa AV, Cinelli MA, Li H, Chreifi G, Mukherjee P, Roman LJ, Martásek P, Poulos TL, Silverman RB.
    J Med Chem; 2017 Aug 24; 60(16):7146-7165. PubMed ID: 28776992
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  • 20. Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity.
    Kang S, Tang W, Li H, Chreifi G, Martásek P, Roman LJ, Poulos TL, Silverman RB.
    J Med Chem; 2014 May 22; 57(10):4382-96. PubMed ID: 24758147
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