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206 related items for PubMed ID: 17041250

  • 1. The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors.
    Breit A, Wolff K, Kalwa H, Jarry H, Büch T, Gudermann T.
    J Biol Chem; 2006 Dec 08; 281(49):37447-56. PubMed ID: 17041250
    [Abstract] [Full Text] [Related]

  • 2. Biased signaling initiated by agouti-related peptide through human melanocortin-3 and -4 receptors.
    Yang Z, Tao YX.
    Biochim Biophys Acta; 2016 Sep 08; 1862(9):1485-94. PubMed ID: 27208795
    [Abstract] [Full Text] [Related]

  • 3. Characterization of Agouti-related protein binding to melanocortin receptors.
    Yang YK, Thompson DA, Dickinson CJ, Wilken J, Barsh GS, Kent SB, Gantz I.
    Mol Endocrinol; 1999 Jan 08; 13(1):148-55. PubMed ID: 9892020
    [Abstract] [Full Text] [Related]

  • 4. Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization.
    Shinyama H, Masuzaki H, Fang H, Flier JS.
    Endocrinology; 2003 Apr 08; 144(4):1301-14. PubMed ID: 12639913
    [Abstract] [Full Text] [Related]

  • 5. Constitutive activity of neural melanocortin receptors.
    Tao YX, Huang H, Wang ZQ, Yang F, Williams JN, Nikiforovich GV.
    Methods Enzymol; 2010 Apr 08; 484():267-79. PubMed ID: 21036237
    [Abstract] [Full Text] [Related]

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  • 7. Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R.
    Ericson MD, Haslach EM, Schnell SM, Freeman KT, Xiang ZM, Portillo FP, Speth R, Litherland SA, Haskell-Luevano C.
    ACS Chem Neurosci; 2021 Feb 03; 12(3):542-556. PubMed ID: 33470098
    [Abstract] [Full Text] [Related]

  • 8. Molecular basis of melanocortin-4 receptor for AGRP inverse agonism.
    Chen M, Celik A, Georgeson KE, Harmon CM, Yang Y.
    Regul Pept; 2006 Sep 11; 136(1-3):40-9. PubMed ID: 16820227
    [Abstract] [Full Text] [Related]

  • 9. Elongation studies of the human agouti-related protein (AGRP) core decapeptide (Yc[CRFFNAFC]Y) results in antagonism at the mouse melanocortin-3 receptor.
    Joseph CG, Bauzo RM, Xiang Z, Shaw AM, Millard WJ, Haskell-Luevano C.
    Peptides; 2003 Feb 11; 24(2):263-70. PubMed ID: 12668211
    [Abstract] [Full Text] [Related]

  • 10. Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, Agouti protein.
    Oosterom J, Garner KM, den Dekker WK, Nijenhuis WA, Gispen WH, Burbach JP, Barsh GS, Adan RA.
    J Biol Chem; 2001 Jan 12; 276(2):931-6. PubMed ID: 11024027
    [Abstract] [Full Text] [Related]

  • 11. The MC4 receptor and control of appetite.
    Adan RA, Tiesjema B, Hillebrand JJ, la Fleur SE, Kas MJ, de Krom M.
    Br J Pharmacol; 2006 Dec 12; 149(7):815-27. PubMed ID: 17043670
    [Abstract] [Full Text] [Related]

  • 12. Phosphodiesterase inhibitor-dependent inverse agonism of agouti-related protein on melanocortin 4 receptor in sea bass (Dicentrarchus labrax).
    Sánchez E, Rubio VC, Thompson D, Metz J, Flik G, Millhauser GL, Cerdá-Reverter JM.
    Am J Physiol Regul Integr Comp Physiol; 2009 May 12; 296(5):R1293-306. PubMed ID: 19225141
    [Abstract] [Full Text] [Related]

  • 13. Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances.
    Smith MA, Hisadome K, Al-Qassab H, Heffron H, Withers DJ, Ashford ML.
    J Physiol; 2007 Jan 15; 578(Pt 2):425-38. PubMed ID: 17068101
    [Abstract] [Full Text] [Related]

  • 14. Structural Complexity and Plasticity of Signaling Regulation at the Melanocortin-4 Receptor.
    Kleinau G, Heyder NA, Tao YX, Scheerer P.
    Int J Mol Sci; 2020 Aug 10; 21(16):. PubMed ID: 32785054
    [Abstract] [Full Text] [Related]

  • 15. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A, Wang XS, Joseph CG, Xiang Z, Bauzo RM, Scott JW, Sorensen NB, Shaw AM, Millard WJ, Richards NG, Haskell-Luevano C.
    J Med Chem; 2004 Apr 22; 47(9):2194-207. PubMed ID: 15084118
    [Abstract] [Full Text] [Related]

  • 16. Molecular determination of agouti-related protein binding to human melanocortin-4 receptor.
    Yang Y, Chen M, Lai Y, Gantz I, Yagmurlu A, Georgeson KE, Harmon CM.
    Mol Pharmacol; 2003 Jul 22; 64(1):94-103. PubMed ID: 12815165
    [Abstract] [Full Text] [Related]

  • 17. Loss of agouti-related peptide does not significantly impact the phenotype of murine POMC deficiency.
    Corander MP, Rimmington D, Challis BG, O'Rahilly S, Coll AP.
    Endocrinology; 2011 May 22; 152(5):1819-28. PubMed ID: 21363936
    [Abstract] [Full Text] [Related]

  • 18. Ac-Trp-DPhe(p-I)-Arg-Trp-NH2, a 250-Fold Selective Melanocortin-4 Receptor (MC4R) Antagonist over the Melanocortin-3 Receptor (MC3R), Affects Energy Homeostasis in Male and Female Mice Differently.
    Lensing CJ, Adank DN, Doering SR, Wilber SL, Andreasen A, Schaub JW, Xiang Z, Haskell-Luevano C.
    ACS Chem Neurosci; 2016 Sep 21; 7(9):1283-91. PubMed ID: 27385405
    [Abstract] [Full Text] [Related]

  • 19. Beta-arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor.
    Jones BW, Hinkle PM.
    J Biol Chem; 2005 Nov 18; 280(46):38346-54. PubMed ID: 16183993
    [Abstract] [Full Text] [Related]

  • 20. The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.
    Tohgo A, Choy EW, Gesty-Palmer D, Pierce KL, Laporte S, Oakley RH, Caron MG, Lefkowitz RJ, Luttrell LM.
    J Biol Chem; 2003 Feb 21; 278(8):6258-67. PubMed ID: 12473660
    [Abstract] [Full Text] [Related]

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