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698 related items for PubMed ID: 17051334

  • 1. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S, Borrow J, Zhang XD, Hersey P.
    Apoptosis; 2006 Dec; 11(12):2251-65. PubMed ID: 17051334
    [Abstract] [Full Text] [Related]

  • 2. The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.
    Zhang XD, Gillespie SK, Borrow JM, Hersey P.
    Mol Cancer Ther; 2004 Apr; 3(4):425-35. PubMed ID: 15078986
    [Abstract] [Full Text] [Related]

  • 3. The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.
    Zhang XD, Gillespie SK, Borrow JM, Hersey P.
    Biochem Pharmacol; 2003 Oct 15; 66(8):1537-45. PubMed ID: 14555232
    [Abstract] [Full Text] [Related]

  • 4. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.
    J Biol Chem; 2011 Mar 18; 286(11):9382-92. PubMed ID: 21148306
    [Abstract] [Full Text] [Related]

  • 5. Bim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.
    Chen S, Dai Y, Pei XY, Grant S.
    Mol Cell Biol; 2009 Dec 18; 29(23):6149-69. PubMed ID: 19805519
    [Abstract] [Full Text] [Related]

  • 6. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
    Sung ES, Park KJ, Choi HJ, Kim CH, Kim YS.
    Exp Cell Res; 2012 Aug 01; 318(13):1564-76. PubMed ID: 22513214
    [Abstract] [Full Text] [Related]

  • 7. Interactive effects of histone deacetylase inhibitors and TRAIL on apoptosis in human leukemia cells: involvement of both death receptor and mitochondrial pathways.
    Shankar S, Singh TR, Fandy TE, Luetrakul T, Ross DD, Srivastava RK.
    Int J Mol Med; 2005 Dec 01; 16(6):1125-38. PubMed ID: 16273296
    [Abstract] [Full Text] [Related]

  • 8. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 9. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation.
    Rosato RR, Almenara JA, Coe S, Grant S.
    Cancer Res; 2007 Oct 01; 67(19):9490-500. PubMed ID: 17909059
    [Abstract] [Full Text] [Related]

  • 10. Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins.
    Werneburg NW, Guicciardi ME, Bronk SF, Kaufmann SH, Gores GJ.
    J Biol Chem; 2007 Sep 28; 282(39):28960-28970. PubMed ID: 17686764
    [Abstract] [Full Text] [Related]

  • 11. Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.
    Meng XW, Lee SH, Dai H, Loegering D, Yu C, Flatten K, Schneider P, Dai NT, Kumar SK, Smith BD, Karp JE, Adjei AA, Kaufmann SH.
    J Biol Chem; 2007 Oct 12; 282(41):29831-46. PubMed ID: 17698840
    [Abstract] [Full Text] [Related]

  • 12. Combined treatment with Ad-hTRAIL and DTIC or SAHA is associated with increased mitochondrial-mediated apoptosis in human melanoma cell lines.
    Lillehammer T, Engesaeter BO, Prasmickaite L, Maelandsmo GM, Fodstad O, Engebraaten O.
    J Gene Med; 2007 Jun 12; 9(6):440-51. PubMed ID: 17410615
    [Abstract] [Full Text] [Related]

  • 13. Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.
    Wang YF, Jiang CC, Kiejda KA, Gillespie S, Zhang XD, Hersey P.
    Clin Cancer Res; 2007 Aug 15; 13(16):4934-42. PubMed ID: 17652623
    [Abstract] [Full Text] [Related]

  • 14. Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation.
    Rosato RR, Dai Y, Almenara JA, Maggio SC, Grant S.
    Leukemia; 2004 Nov 15; 18(11):1780-8. PubMed ID: 15385934
    [Abstract] [Full Text] [Related]

  • 15. Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.
    Lim DY, Park JH.
    Am J Physiol Gastrointest Liver Physiol; 2009 May 15; 296(5):G1060-8. PubMed ID: 19264955
    [Abstract] [Full Text] [Related]

  • 16. Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis.
    Han J, Goldstein LA, Gastman BR, Rabinowich H.
    J Biol Chem; 2006 Apr 14; 281(15):10153-63. PubMed ID: 16478725
    [Abstract] [Full Text] [Related]

  • 17. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2006 Dec 14; 8(12):1348-58. PubMed ID: 17115033
    [Abstract] [Full Text] [Related]

  • 18. BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells.
    Huang S, Okumura K, Sinicrope FA.
    Clin Cancer Res; 2009 Jan 01; 15(1):150-9. PubMed ID: 19118042
    [Abstract] [Full Text] [Related]

  • 19. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
    Sinicrope FA, Penington RC, Tang XM.
    Clin Cancer Res; 2004 Dec 15; 10(24):8284-92. PubMed ID: 15623604
    [Abstract] [Full Text] [Related]

  • 20. c-Myc overexpression sensitizes Bim-mediated Bax activation for apoptosis induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through regulating Bcl-2/Bcl-xL expression.
    Jiang X, Tsang YH, Yu Q.
    Int J Biochem Cell Biol; 2007 Dec 15; 39(5):1016-25. PubMed ID: 17331788
    [Abstract] [Full Text] [Related]

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