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650 related items for PubMed ID: 17052966

  • 1. Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.
    Pogrebniak A, Schemainda I, Azzam K, Pelka-Fleischer R, Nüssler V, Hasmann M.
    Eur J Med Res; 2006 Aug 30; 11(8):313-21. PubMed ID: 17052966
    [Abstract] [Full Text] [Related]

  • 2. Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.
    Pogrebniak A, Schemainda I, Pelka-Fleischer R, Nüssler V, Hasmann M.
    Eur J Med Res; 2003 Oct 22; 8(10):438-50. PubMed ID: 14594650
    [Abstract] [Full Text] [Related]

  • 3. Anticancer agent CHS-828 inhibits cellular synthesis of NAD.
    Olesen UH, Christensen MK, Björkling F, Jäättelä M, Jensen PB, Sehested M, Nielsen SJ.
    Biochem Biophys Res Commun; 2008 Mar 21; 367(4):799-804. PubMed ID: 18201551
    [Abstract] [Full Text] [Related]

  • 4. Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy.
    Muruganandham M, Alfieri AA, Matei C, Chen Y, Sukenick G, Schemainda I, Hasmann M, Saltz LB, Koutcher JA.
    Clin Cancer Res; 2005 May 01; 11(9):3503-13. PubMed ID: 15867253
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  • 5. Cytoprotective features of selenazofurin in hematopoietic cells.
    Pogrebniak A, Hasmann M, Schemainda I, Pelka-Fleischer R, Nuessler V.
    Int J Clin Pharmacol Ther; 2002 Aug 01; 40(8):368-75. PubMed ID: 12467305
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of isosteric analogues of FK866, an inhibitor of NAD salvage.
    Galli U, Ercolano E, Carraro L, Blasi Roman CR, Sorba G, Canonico PL, Genazzani AA, Tron GC, Billington RA.
    ChemMedChem; 2008 May 01; 3(5):771-9. PubMed ID: 18247435
    [Abstract] [Full Text] [Related]

  • 7. Overexpression of Nampt in gastric cancer and chemopotentiating effects of the Nampt inhibitor FK866 in combination with fluorouracil.
    Bi TQ, Che XM, Liao XH, Zhang DJ, Long HL, Li HJ, Zhao W.
    Oncol Rep; 2011 Nov 01; 26(5):1251-7. PubMed ID: 21743967
    [Abstract] [Full Text] [Related]

  • 8. Human stem cell factor-antibody [anti-SCF] enhances chemotherapy cytotoxicity in human CD34+ resistant myeloid leukaemia cells.
    Lu C, Hassan HT.
    Leuk Res; 2006 Mar 01; 30(3):296-302. PubMed ID: 16112192
    [Abstract] [Full Text] [Related]

  • 9. Circumvention of ara-C resistance by aphidicolin in blast cells from patients with AML.
    Sargent JM, Elgie AW, Williamson CJ, Lewandowicz GM, Taylor CG.
    Br J Cancer; 2001 Mar 02; 84(5):680-5. PubMed ID: 11237390
    [Abstract] [Full Text] [Related]

  • 10. FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
    Hasmann M, Schemainda I.
    Cancer Res; 2003 Nov 01; 63(21):7436-42. PubMed ID: 14612543
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of ribonucleotide reductase by a new class of isoindole derivatives: drug synergism with cytarabine (Ara-C) and induction of cellular apoptosis.
    Nandy P, Lien EJ, Avramis VI.
    Anticancer Res; 1999 Nov 01; 19(3A):1625-33. PubMed ID: 10470093
    [Abstract] [Full Text] [Related]

  • 12. Non-apoptogenic killing of hela cervical carcinoma cells after short exposure to the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
    Wesierska-Gadek J, Gueorguieva M, Schloffer D, Uhl M, Wojciechowski J.
    J Cell Biochem; 2003 Aug 15; 89(6):1222-34. PubMed ID: 12898520
    [Abstract] [Full Text] [Related]

  • 13. Evaluation of cell-killing effects of 1-beta-D-arabinofuranosylcytosine and daunorubicin by a new computer-controlled in vitro pharmacokinetic simulation system.
    Kishi S, Goto N, Nakamura T, Ueda T.
    Cancer Res; 1999 Jun 01; 59(11):2629-34. PubMed ID: 10363985
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of poly(ADP-ribose) polymerase (PARP) influences the mode of sulfur mustard (SM)-induced cell death in HaCaT cells.
    Kehe K, Raithel K, Kreppel H, Jochum M, Worek F, Thiermann H.
    Arch Toxicol; 2008 Jul 01; 82(7):461-70. PubMed ID: 18046540
    [Abstract] [Full Text] [Related]

  • 15. Effect of cloretazine (VNP40101M) on acute myeloid leukaemia blast cells in vitro as a single agent and combined with cytarabine and daunorubicin.
    Morris KL, Adams JA, Liu Yin JA.
    Leuk Res; 2009 Aug 01; 33(8):1096-9. PubMed ID: 19268363
    [Abstract] [Full Text] [Related]

  • 16. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb 01; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

  • 17. Kinetics and mechanism of the 1-beta-D-arabinofuranosylcytosine-induced potentiation of cis-diamminedichloroplatinum(II) cytotoxicity.
    Vadi H, Drewinko B.
    Cancer Res; 1986 Mar 01; 46(3):1105-9. PubMed ID: 3080232
    [Abstract] [Full Text] [Related]

  • 18. On-target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells.
    Gehrke I, Bouchard ED, Beiggi S, Poeppl AG, Johnston JB, Gibson SB, Banerji V.
    Clin Cancer Res; 2014 Sep 15; 20(18):4861-72. PubMed ID: 25172933
    [Abstract] [Full Text] [Related]

  • 19. Reciprocal potentiation of the antitumoral activities of FK866, an inhibitor of nicotinamide phosphoribosyltransferase, and etoposide or cisplatin in neuroblastoma cells.
    Travelli C, Drago V, Maldi E, Kaludercic N, Galli U, Boldorini R, Di Lisa F, Tron GC, Canonico PL, Genazzani AA.
    J Pharmacol Exp Ther; 2011 Sep 15; 338(3):829-40. PubMed ID: 21685314
    [Abstract] [Full Text] [Related]

  • 20. [Bcl-2 antisense oligodeoxynucleotide enhances araninosyl cytosine-induced apoptosis of primary leukemia cells].
    Lei XY, Zhang H, He DM.
    Ai Zheng; 2002 Dec 15; 21(12):1301-4. PubMed ID: 12520735
    [Abstract] [Full Text] [Related]

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