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157 related items for PubMed ID: 17056525

  • 1. A CD8/Lck transgene is able to drive thymocyte differentiation.
    Fragoso RC, Pyarajan S, Irie HY, Burakoff SJ.
    J Immunol; 2006 Nov 01; 177(9):6007-17. PubMed ID: 17056525
    [Abstract] [Full Text] [Related]

  • 2. Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors.
    Trobridge PA, Forbush KA, Levin SD.
    J Immunol; 2001 Jan 15; 166(2):809-18. PubMed ID: 11145654
    [Abstract] [Full Text] [Related]

  • 3. Activated p56lck directs maturation of both CD4 and CD8 single-positive thymocytes.
    Sohn SJ, Forbush KA, Pan XC, Perlmutter RM.
    J Immunol; 2001 Feb 15; 166(4):2209-17. PubMed ID: 11160274
    [Abstract] [Full Text] [Related]

  • 4. T-cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages.
    Chiang YJ, Hodes RJ.
    Eur J Immunol; 2016 Oct 15; 46(10):2401-2408. PubMed ID: 27469439
    [Abstract] [Full Text] [Related]

  • 5. Thymocyte cell fate alteration by high levels of CD8alpha is independent of CD8-lck association.
    Smith DH, Lee N, Lacy E.
    J Immunol; 1996 Aug 01; 157(3):1087-95. PubMed ID: 8757613
    [Abstract] [Full Text] [Related]

  • 6. CD8 expression up to the double-positive CD3(low/intermediate) stage of thymic differentiation is sufficient for development of peripheral functional cytotoxic T lymphocytes.
    Zhang XL, Zhao S, Borenstein SH, Liu Y, Jayabalasingham B, Chamberlain JW.
    J Exp Med; 2001 Sep 03; 194(5):685-93. PubMed ID: 11535636
    [Abstract] [Full Text] [Related]

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  • 8. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.
    Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A.
    J Exp Med; 1993 Nov 01; 178(5):1701-12. PubMed ID: 8228817
    [Abstract] [Full Text] [Related]

  • 9. Lck domains differentially contribute to pre-T cell receptor (TCR)- and TCR-alpha/beta-regulated developmental transitions.
    Lin K, Longo NS, Wang X, Hewitt JA, Abraham KM.
    J Exp Med; 2000 Feb 21; 191(4):703-16. PubMed ID: 10684862
    [Abstract] [Full Text] [Related]

  • 10. ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
    Ashe JM, Wiest DL, Abe R, Singer A.
    J Exp Med; 1999 Apr 05; 189(7):1163-8. PubMed ID: 10190908
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  • 12. Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.
    Casas J, Brzostek J, Zarnitsyna VI, Hong JS, Wei Q, Hoerter JA, Fu G, Ampudia J, Zamoyska R, Zhu C, Gascoigne NR.
    Nat Commun; 2014 Nov 27; 5():5624. PubMed ID: 25427562
    [Abstract] [Full Text] [Related]

  • 13. Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.
    Erman B, Alag AS, Dahle O, van Laethem F, Sarafova SD, Guinter TI, Sharrow SO, Grinberg A, Love PE, Singer A.
    J Immunol; 2006 Nov 15; 177(10):6613-25. PubMed ID: 17082573
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  • 15. An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.
    Mombaerts P, Anderson SJ, Perlmutter RM, Mak TW, Tonegawa S.
    Immunity; 1994 Jul 15; 1(4):261-7. PubMed ID: 7889413
    [Abstract] [Full Text] [Related]

  • 16. Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity.
    Shimizu C, Kawamoto H, Yamashita M, Kimura M, Kondou E, Kaneko Y, Okada S, Tokuhisa T, Yokoyama M, Taniguchi M, Katsura Y, Nakayama T.
    Int Immunol; 2001 Jan 15; 13(1):105-17. PubMed ID: 11133839
    [Abstract] [Full Text] [Related]

  • 17. Changes in the role of the CD45 protein tyrosine phosphatase in regulating Lck tyrosine phosphorylation during thymic development.
    Falahati R, Leitenberg D.
    J Immunol; 2007 Feb 15; 178(4):2056-64. PubMed ID: 17277109
    [Abstract] [Full Text] [Related]

  • 18. Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor.
    Norment AM, Forbush KA, Nguyen N, Malissen M, Perlmutter RM.
    J Exp Med; 1997 Jan 06; 185(1):121-30. PubMed ID: 8996248
    [Abstract] [Full Text] [Related]

  • 19. Enhanced T cell maturation and altered lineage commitment in T cell receptor/CD4-transgenic mice.
    Lieberman SA, Spain LM, Wang L, Berg LJ.
    Cell Immunol; 1995 Apr 15; 162(1):56-67. PubMed ID: 7704911
    [Abstract] [Full Text] [Related]

  • 20. Regulation of T cell development by c-Cbl: essential role of Lck.
    Chiang YJ, Hodes RJ.
    Int Immunol; 2015 May 15; 27(5):245-51. PubMed ID: 25477210
    [Abstract] [Full Text] [Related]

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