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Journal Abstract Search


176 related items for PubMed ID: 17058234

  • 1. Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver.
    Trottier J, Verreault M, Grepper S, Monté D, Bélanger J, Kaeding J, Caron P, Inaba TT, Barbier O.
    Hepatology; 2006 Nov; 44(5):1158-70. PubMed ID: 17058234
    [Abstract] [Full Text] [Related]

  • 2. Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids.
    Erichsen TJ, Aehlen A, Ehmer U, Kalthoff S, Manns MP, Strassburg CP.
    J Hepatol; 2010 Apr; 52(4):570-8. PubMed ID: 20189675
    [Abstract] [Full Text] [Related]

  • 3. The liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGT1A3 enzyme in human cells and transgenic mice.
    Verreault M, Senekeo-Effenberger K, Trottier J, Bonzo JA, Bélanger J, Kaeding J, Staels B, Caron P, Tukey RH, Barbier O.
    Hepatology; 2006 Aug; 44(2):368-78. PubMed ID: 16871576
    [Abstract] [Full Text] [Related]

  • 4. Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases.
    Yu L, Lu S, Lin Y, Zeng S.
    Biochem Pharmacol; 2007 Jun 01; 73(11):1842-51. PubMed ID: 17359941
    [Abstract] [Full Text] [Related]

  • 5. Human UDP-glucuronosyltransferase isoforms involved in bisphenol A glucuronidation.
    Hanioka N, Naito T, Narimatsu S.
    Chemosphere; 2008 Dec 01; 74(1):33-6. PubMed ID: 18990428
    [Abstract] [Full Text] [Related]

  • 6. Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme.
    Barbier O, Duran-Sandoval D, Pineda-Torra I, Kosykh V, Fruchart JC, Staels B.
    J Biol Chem; 2003 Aug 29; 278(35):32852-60. PubMed ID: 12810707
    [Abstract] [Full Text] [Related]

  • 7. Bile acids reduce SR-BI expression in hepatocytes by a pathway involving FXR/RXR, SHP, and LRH-1.
    Malerød L, Sporstøl M, Juvet LK, Mousavi SA, Gjøen T, Berg T, Roos N, Eskild W.
    Biochem Biophys Res Commun; 2005 Nov 04; 336(4):1096-105. PubMed ID: 16168958
    [Abstract] [Full Text] [Related]

  • 8. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R, Nakajima M, Yamanaka H, Katoh M, Yokoi T.
    Drug Metab Dispos; 2008 Feb 04; 36(2):361-7. PubMed ID: 17998297
    [Abstract] [Full Text] [Related]

  • 9. Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy.
    Xing X, Burgermeister E, Geisler F, Einwächter H, Fan L, Hiber M, Rauser S, Walch A, Röcken C, Ebeling M, Wright MB, Schmid RM, Ebert MP.
    Hepatology; 2009 Mar 04; 49(3):979-88. PubMed ID: 19072826
    [Abstract] [Full Text] [Related]

  • 10. Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: role of acyl glucuronide metabolites and glycation pathways.
    Southwood HT, DeGraaf YC, Mackenzie PI, Miners JO, Burcham PC, Sallustio BC.
    Chem Res Toxicol; 2007 Oct 04; 20(10):1520-7. PubMed ID: 17880178
    [Abstract] [Full Text] [Related]

  • 11. Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation.
    Senekeo-Effenberger K, Chen S, Brace-Sinnokrak E, Bonzo JA, Yueh MF, Argikar U, Kaeding J, Trottier J, Remmel RP, Ritter JK, Barbier O, Tukey RH.
    Drug Metab Dispos; 2007 Mar 04; 35(3):419-27. PubMed ID: 17151188
    [Abstract] [Full Text] [Related]

  • 12. The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation.
    Perreault M, Gauthier-Landry L, Trottier J, Verreault M, Caron P, Finel M, Barbier O.
    Drug Metab Dispos; 2013 Sep 04; 41(9):1616-20. PubMed ID: 23756265
    [Abstract] [Full Text] [Related]

  • 13. Regio- and stereospecific N-glucuronidation of medetomidine: the differences between UDP glucuronosyltransferase (UGT) 1A4 and UGT2B10 account for the complex kinetics of human liver microsomes.
    Kaivosaari S, Toivonen P, Aitio O, Sipilä J, Koskinen M, Salonen JS, Finel M.
    Drug Metab Dispos; 2008 Aug 04; 36(8):1529-37. PubMed ID: 18474681
    [Abstract] [Full Text] [Related]

  • 14. UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics.
    Wen Z, Tallman MN, Ali SY, Smith PC.
    Drug Metab Dispos; 2007 Mar 04; 35(3):371-80. PubMed ID: 17151191
    [Abstract] [Full Text] [Related]

  • 15. Glucuronidation of anti-HIV drug candidate bevirimat: identification of human UDP-glucuronosyltransferases and species differences.
    Wen Z, Martin DE, Bullock P, Lee KH, Smith PC.
    Drug Metab Dispos; 2007 Mar 04; 35(3):440-8. PubMed ID: 17151190
    [Abstract] [Full Text] [Related]

  • 16. Involvement of multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes in the in vitro metabolism of muraglitazar.
    Zhang D, Wang L, Chandrasena G, Ma L, Zhu M, Zhang H, Davis CD, Humphreys WG.
    Drug Metab Dispos; 2007 Jan 04; 35(1):139-49. PubMed ID: 17062778
    [Abstract] [Full Text] [Related]

  • 17. Effect of chenodeoxycholic acid and ursodeoxycholic acid administration on acyl-CoA: cholesterol acyltransferase activity in human liver.
    Abate N, Carubbi F, Bozzoli M, Bertolotti M, Farah I, Rosi A, Carulli N.
    Ital J Gastroenterol; 1994 Jan 04; 26(6):287-93. PubMed ID: 7949265
    [Abstract] [Full Text] [Related]

  • 18. Hepatic and extrahepatic glucuronidation of bile acids in man. Characterization of bile acid uridine 5'-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes.
    Matern S, Matern H, Farthmann EH, Gerok W.
    J Clin Invest; 1984 Aug 04; 74(2):402-10. PubMed ID: 6430960
    [Abstract] [Full Text] [Related]

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