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Journal Abstract Search

708 related items for PubMed ID: 17064062

  • 1. 3-aminoquinazolinediones as a new class of antibacterial agents demonstrating excellent antibacterial activity against wild-type and multidrug resistant organisms.
    Ellsworth EL, Tran TP, Showalter HD, Sanchez JP, Watson BM, Stier MA, Domagala JM, Gracheck SJ, Joannides ET, Shapiro MA, Dunham SA, Hanna DL, Huband MD, Gage JW, Bronstein JC, Liu JY, Nguyen DQ, Singh R.
    J Med Chem; 2006 Nov 02; 49(22):6435-8. PubMed ID: 17064062
    [Abstract] [Full Text] [Related]

  • 2. Structure-activity relationships of 3-aminoquinazolinediones, a new class of bacterial type-2 topoisomerase (DNA gyrase and topo IV) inhibitors.
    Tran TP, Ellsworth EL, Sanchez JP, Watson BM, Stier MA, Showalter HD, Domagala JM, Shapiro MA, Joannides ET, Gracheck SJ, Nguyen DQ, Bird P, Yip J, Sharadendu A, Ha C, Ramezani S, Wu X, Singh R.
    Bioorg Med Chem Lett; 2007 Mar 01; 17(5):1312-20. PubMed ID: 17196390
    [Abstract] [Full Text] [Related]

  • 3. Quercetin diacylglycoside analogues showing dual inhibition of DNA gyrase and topoisomerase IV as novel antibacterial agents.
    Hossion AM, Zamami Y, Kandahary RK, Tsuchiya T, Ogawa W, Iwado A, Sasaki K.
    J Med Chem; 2011 Jun 09; 54(11):3686-703. PubMed ID: 21534606
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and structure-activity relationship studies of novel indazole analogues as DNA gyrase inhibitors with Gram-positive antibacterial activity.
    Tanitame A, Oyamada Y, Ofuji K, Kyoya Y, Suzuki K, Ito H, Kawasaki M, Nagai K, Wachi M, Yamagishi J.
    Bioorg Med Chem Lett; 2004 Jun 07; 14(11):2857-62. PubMed ID: 15125947
    [Abstract] [Full Text] [Related]

  • 5. Isothiazolopyridones: synthesis, structure, and biological activity of a new class of antibacterial agents.
    Wiles JA, Hashimoto A, Thanassi JA, Cheng J, Incarvito CD, Deshpande M, Pucci MJ, Bradbury BJ.
    J Med Chem; 2006 Jan 12; 49(1):39-42. PubMed ID: 16392790
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and antibacterial activity of the C-7 side chain of 3-aminoquinazolinediones.
    Hutchings KM, Tran TP, Ellsworth EL, Watson BM, Sanchez JP, Showalter HD, Stier MA, Shapiro M, Themis Joannides E, Huband M, Nguyen DQ, Maiti S, Li T, Tailor J, Thomas G, Ha C, Singh R.
    Bioorg Med Chem Lett; 2008 Sep 15; 18(18):5087-90. PubMed ID: 18752951
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis, and evaluation of novel fluoroquinolone-aminoglycoside hybrid antibiotics.
    Pokrovskaya V, Belakhov V, Hainrichson M, Yaron S, Baasov T.
    J Med Chem; 2009 Apr 23; 52(8):2243-54. PubMed ID: 19301822
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and structure-activity relationships of 2-pyridones: a novel series of potent DNA gyrase inhibitors as antibacterial agents.
    Li Q, Chu DT, Claiborne A, Cooper CS, Lee CM, Raye K, Berst KB, Donner P, Wang W, Hasvold L, Fung A, Ma Z, Tufano M, Flamm R, Shen LL, Baranowski J, Nilius A, Alder J, Meulbroek J, Marsh K, Crowell D, Hui Y, Seif L, Melcher LM, Plattner JJ.
    J Med Chem; 1996 Aug 02; 39(16):3070-88. PubMed ID: 8759628
    [Abstract] [Full Text] [Related]

  • 9. Potent DNA gyrase inhibitors; novel 5-vinylpyrazole analogues with Gram-positive antibacterial activity.
    Tanitame A, Oyamada Y, Ofuji K, Suzuki K, Ito H, Kawasaki M, Wachi M, Yamagishi J.
    Bioorg Med Chem Lett; 2004 Jun 07; 14(11):2863-6. PubMed ID: 15125948
    [Abstract] [Full Text] [Related]

  • 10. Novel dual-targeting benzimidazole urea inhibitors of DNA gyrase and topoisomerase IV possessing potent antibacterial activity: intelligent design and evolution through the judicious use of structure-guided design and structure-activity relationships.
    Charifson PS, Grillot AL, Grossman TH, Parsons JD, Badia M, Bellon S, Deininger DD, Drumm JE, Gross CH, LeTiran A, Liao Y, Mani N, Nicolau DP, Perola E, Ronkin S, Shannon D, Swenson LL, Tang Q, Tessier PR, Tian SK, Trudeau M, Wang T, Wei Y, Zhang H, Stamos D.
    J Med Chem; 2008 Sep 11; 51(17):5243-63. PubMed ID: 18690678
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and antibacterial activity of a novel series of DNA gyrase inhibitors: 5-[(E)-2-arylvinyl]pyrazoles.
    Tanitame A, Oyamada Y, Ofuji K, Terauchi H, Kawasaki M, Wachi M, Yamagishi J.
    Bioorg Med Chem Lett; 2005 Oct 01; 15(19):4299-303. PubMed ID: 16087337
    [Abstract] [Full Text] [Related]

  • 12. New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine.
    Angehrn P, Buchmann S, Funk C, Goetschi E, Gmuender H, Hebeisen P, Kostrewa D, Link H, Luebbers T, Masciadri R, Nielsen J, Reindl P, Ricklin F, Schmitt-Hoffmann A, Theil FP.
    J Med Chem; 2004 Mar 11; 47(6):1487-513. PubMed ID: 14998336
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and antibacterial activity of a novel series of potent DNA gyrase inhibitors. Pyrazole derivatives.
    Tanitame A, Oyamada Y, Ofuji K, Fujimoto M, Iwai N, Hiyama Y, Suzuki K, Ito H, Terauchi H, Kawasaki M, Nagai K, Wachi M, Yamagishi J.
    J Med Chem; 2004 Jul 01; 47(14):3693-6. PubMed ID: 15214796
    [Abstract] [Full Text] [Related]

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  • 15. Discovery of (3S)-amino-(4R)-ethylpiperidinyl quinolones as potent antibacterial agents with a broad spectrum of activity and activity against resistant pathogens.
    Hu XE, Kim NK, Gray JL, Almstead JI, Seibel WL, Ledoussal B.
    J Med Chem; 2003 Aug 14; 46(17):3655-61. PubMed ID: 12904069
    [Abstract] [Full Text] [Related]

  • 16. In vitro antibacterial activity of aminosterols against multidrug-resistant bacteria from patients with cystic fibrosis.
    Alhanout K, Brunel JM, Raoult D, Rolain JM.
    J Antimicrob Chemother; 2009 Oct 14; 64(4):810-4. PubMed ID: 19666647
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological activity of novel antibacterial quinazolines.
    Bedi PM, Kumar V, Mahajan MP.
    Bioorg Med Chem Lett; 2004 Oct 18; 14(20):5211-3. PubMed ID: 15380229
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and antibacterial activity of novel and potent DNA gyrase inhibitors with azole ring.
    Tanitame A, Oyamada Y, Ofuji K, Fujimoto M, Suzuki K, Ueda T, Terauchi H, Kawasaki M, Nagai K, Wachi M, Yamagishi J.
    Bioorg Med Chem; 2004 Nov 01; 12(21):5515-24. PubMed ID: 15465328
    [Abstract] [Full Text] [Related]

  • 19. The synthesis and biological evaluation of novel series of nitrile-containing fluoroquinolones as antibacterial agents.
    Murphy ST, Case HL, Ellsworth E, Hagen S, Huband M, Joannides T, Limberakis C, Marotti KR, Ottolini AM, Rauckhorst M, Starr J, Stier M, Taylor C, Zhu T, Blaser A, Denny WA, Lu GL, Smaill JB, Rivault F.
    Bioorg Med Chem Lett; 2007 Apr 15; 17(8):2150-5. PubMed ID: 17303420
    [Abstract] [Full Text] [Related]

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