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PUBMED FOR HANDHELDS

Journal Abstract Search


145 related items for PubMed ID: 17090658

  • 1. Mutations within the membrane domain of HMG-CoA reductase confer resistance to sterol-accelerated degradation.
    Lee PC, Nguyen AD, Debose-Boyd RA.
    J Lipid Res; 2007 Feb; 48(2):318-27. PubMed ID: 17090658
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  • 2. Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.
    Jiang LY, Jiang W, Tian N, Xiong YN, Liu J, Wei J, Wu KY, Luo J, Shi XJ, Song BL.
    J Biol Chem; 2018 Mar 16; 293(11):4047-4055. PubMed ID: 29374057
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  • 5. Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells.
    Lee PC, DeBose-Boyd RA.
    J Lipid Res; 2010 Jan 16; 51(1):192-201. PubMed ID: 19617589
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  • 8. Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Sever N, Lee PC, Song BL, Rawson RB, Debose-Boyd RA.
    J Biol Chem; 2004 Oct 08; 279(41):43136-47. PubMed ID: 15247248
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  • 9. Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.
    Song BL, Sever N, DeBose-Boyd RA.
    Mol Cell; 2005 Sep 16; 19(6):829-40. PubMed ID: 16168377
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  • 10. Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain.
    Sever N, Yang T, Brown MS, Goldstein JL, DeBose-Boyd RA.
    Mol Cell; 2003 Jan 16; 11(1):25-33. PubMed ID: 12535518
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  • 11. Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells.
    Elsabrouty R, Jo Y, Dinh TT, DeBose-Boyd RA.
    Mol Biol Cell; 2013 Nov 16; 24(21):3300-8. PubMed ID: 24025715
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  • 12. Ubiquitin is conjugated by membrane ubiquitin ligase to three sites, including the N terminus, in transmembrane region of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for sterol-regulated enzyme degradation.
    Doolman R, Leichner GS, Avner R, Roitelman J.
    J Biol Chem; 2004 Sep 10; 279(37):38184-93. PubMed ID: 15247208
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  • 14. The inhibition of degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase by sterol regulatory element binding protein cleavage-activating protein requires four phenylalanine residues in span 6 of HMG-CoA reductase transmembrane domain.
    Xu L, Simoni RD.
    Arch Biochem Biophys; 2003 Jun 15; 414(2):232-43. PubMed ID: 12781775
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  • 15. Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.
    Lee JN, Song B, DeBose-Boyd RA, Ye J.
    J Biol Chem; 2006 Dec 22; 281(51):39308-15. PubMed ID: 17043353
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  • 19. Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum.
    Roitelman J, Olender EH, Bar-Nun S, Dunn WA, Simoni RD.
    J Cell Biol; 1992 Jun 22; 117(5):959-73. PubMed ID: 1374417
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  • 20. Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.
    Tsai YC, Leichner GS, Pearce MM, Wilson GL, Wojcikiewicz RJ, Roitelman J, Weissman AM.
    Mol Biol Cell; 2012 Dec 22; 23(23):4484-94. PubMed ID: 23087214
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