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242 related items for PubMed ID: 17102138

  • 1. Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion.
    Pongratz RL, Kibbey RG, Shulman GI, Cline GW.
    J Biol Chem; 2007 Jan 05; 282(1):200-7. PubMed ID: 17102138
    [Abstract] [Full Text] [Related]

  • 2. Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic β-cells.
    Hasan NM, Longacre MJ, Stoker SW, Kendrick MA, MacDonald MJ.
    Mol Endocrinol; 2015 Mar 05; 29(3):396-410. PubMed ID: 25594249
    [Abstract] [Full Text] [Related]

  • 3. Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets.
    Ronnebaum SM, Jensen MV, Hohmeier HE, Burgess SC, Zhou YP, Qian S, MacNeil D, Howard A, Thornberry N, Ilkayeva O, Lu D, Sherry AD, Newgard CB.
    J Biol Chem; 2008 Oct 24; 283(43):28909-17. PubMed ID: 18755687
    [Abstract] [Full Text] [Related]

  • 4. Chronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line.
    Brown LJ, Longacre MJ, Hasan NM, Kendrick MA, Stoker SW, Macdonald MJ.
    J Biol Chem; 2009 Dec 18; 284(51):35359-67. PubMed ID: 19858194
    [Abstract] [Full Text] [Related]

  • 5. Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion.
    MacDonald MJ.
    J Biol Chem; 1995 Aug 25; 270(34):20051-8. PubMed ID: 7650022
    [Abstract] [Full Text] [Related]

  • 6. Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion.
    Heart E, Cline GW, Collis LP, Pongratz RL, Gray JP, Smith PJ.
    Am J Physiol Endocrinol Metab; 2009 Jun 25; 296(6):E1354-62. PubMed ID: 19293334
    [Abstract] [Full Text] [Related]

  • 7. A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion.
    Guay C, Madiraju SR, Aumais A, Joly E, Prentki M.
    J Biol Chem; 2007 Dec 07; 282(49):35657-65. PubMed ID: 17928289
    [Abstract] [Full Text] [Related]

  • 8. The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.
    Odegaard ML, Joseph JW, Jensen MV, Lu D, Ilkayeva O, Ronnebaum SM, Becker TC, Newgard CB.
    J Biol Chem; 2010 May 28; 285(22):16530-7. PubMed ID: 20356834
    [Abstract] [Full Text] [Related]

  • 9. beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats.
    Liu YQ, Jetton TL, Leahy JL.
    J Biol Chem; 2002 Oct 18; 277(42):39163-8. PubMed ID: 12147706
    [Abstract] [Full Text] [Related]

  • 10. A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion.
    Ronnebaum SM, Ilkayeva O, Burgess SC, Joseph JW, Lu D, Stevens RD, Becker TC, Sherry AD, Newgard CB, Jensen MV.
    J Biol Chem; 2006 Oct 13; 281(41):30593-602. PubMed ID: 16912049
    [Abstract] [Full Text] [Related]

  • 11. Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion.
    Farfari S, Schulz V, Corkey B, Prentki M.
    Diabetes; 2000 May 13; 49(5):718-26. PubMed ID: 10905479
    [Abstract] [Full Text] [Related]

  • 12. Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells.
    MacDonald MJ, Longacre MJ, Kendrick MA.
    Arch Biochem Biophys; 2009 Aug 15; 488(2):100-4. PubMed ID: 19691144
    [Abstract] [Full Text] [Related]

  • 13. The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells.
    Rubi B, del Arco A, Bartley C, Satrustegui J, Maechler P.
    J Biol Chem; 2004 Dec 31; 279(53):55659-66. PubMed ID: 15494407
    [Abstract] [Full Text] [Related]

  • 14. A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells.
    Guay C, Joly E, Pepin E, Barbeau A, Hentsch L, Pineda M, Madiraju SR, Brunengraber H, Prentki M.
    PLoS One; 2013 Dec 31; 8(10):e77097. PubMed ID: 24130841
    [Abstract] [Full Text] [Related]

  • 15. The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells.
    Huypens P, Pillai R, Sheinin T, Schaefer S, Huang M, Odegaard ML, Ronnebaum SM, Wettig SD, Joseph JW.
    Diabetologia; 2011 Jan 31; 54(1):135-45. PubMed ID: 20949348
    [Abstract] [Full Text] [Related]

  • 16. Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.
    Pongratz RL, Kibbey RG, Kirkpatrick CL, Zhao X, Pontoglio M, Yaniv M, Wollheim CB, Shulman GI, Cline GW.
    J Biol Chem; 2009 Jun 19; 284(25):16808-16821. PubMed ID: 19376774
    [Abstract] [Full Text] [Related]

  • 17. Investigating the roles of mitochondrial and cytosolic malic enzyme in insulin secretion.
    Pongratz RL, Kibbey RG, Cline GW.
    Methods Enzymol; 2009 Jun 19; 457():425-50. PubMed ID: 19426882
    [Abstract] [Full Text] [Related]

  • 18. Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.
    Jensen MV, Joseph JW, Ilkayeva O, Burgess S, Lu D, Ronnebaum SM, Odegaard M, Becker TC, Sherry AD, Newgard CB.
    J Biol Chem; 2006 Aug 04; 281(31):22342-22351. PubMed ID: 16740637
    [Abstract] [Full Text] [Related]

  • 19. The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta cells.
    Xu J, Han J, Long YS, Epstein PN, Liu YQ.
    Diabetologia; 2008 Nov 04; 51(11):2022-30. PubMed ID: 18769905
    [Abstract] [Full Text] [Related]

  • 20. Pancreatic islet beta-cells transiently metabolize pyruvate.
    Rocheleau JV, Head WS, Nicholson WE, Powers AC, Piston DW.
    J Biol Chem; 2002 Aug 23; 277(34):30914-20. PubMed ID: 12070148
    [Abstract] [Full Text] [Related]

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