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207 related items for PubMed ID: 17121919
1. Cantharidin-induced mitotic arrest is associated with the formation of aberrant mitotic spindles and lagging chromosomes resulting, in part, from the suppression of PP2Aalpha. Bonness K, Aragon IV, Rutland B, Ofori-Acquah S, Dean NM, Honkanen RE. Mol Cancer Ther; 2006 Nov; 5(11):2727-36. PubMed ID: 17121919 [Abstract] [Full Text] [Related]
2. Fostriecin-mediated G2-M-phase growth arrest correlates with abnormal centrosome replication, the formation of aberrant mitotic spindles, and the inhibition of serine/threonine protein phosphatase activity. Cheng A, Balczon R, Zuo Z, Koons JS, Walsh AH, Honkanen RE. Cancer Res; 1998 Aug 15; 58(16):3611-9. PubMed ID: 9721869 [Abstract] [Full Text] [Related]
3. Suppression of Ser/Thr phosphatase 4 (PP4C/PPP4C) mimics a novel post-mitotic action of fostriecin, producing mitotic slippage followed by tetraploid cell death. Theobald B, Bonness K, Musiyenko A, Andrews JF, Urban G, Huang X, Dean NM, Honkanen RE. Mol Cancer Res; 2013 Aug 15; 11(8):845-55. PubMed ID: 23671329 [Abstract] [Full Text] [Related]
4. Induction of C-anaphase and diplochromosome through dysregulation of spindle assembly checkpoint by sodium arsenite in human fibroblasts. Yih LH, Lee TC. Cancer Res; 2003 Oct 15; 63(20):6680-8. PubMed ID: 14583462 [Abstract] [Full Text] [Related]
5. Alterations in the distribution of histone H3 phosphorylation in mitotic plant chromosomes in response to cold treatment and the protein phosphatase inhibitor cantharidin. Manzanero S, Rutten T, Kotseruba V, Houben A. Chromosome Res; 2002 Oct 15; 10(6):467-76. PubMed ID: 12489829 [Abstract] [Full Text] [Related]
6. Inhibition of mitosis by okadaic acid: possible involvement of a protein phosphatase 2A in the transition from metaphase to anaphase. Vandré DD, Wills VL. J Cell Sci; 1992 Jan 15; 101 ( Pt 1)():79-91. PubMed ID: 1314839 [Abstract] [Full Text] [Related]
7. Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues. Sakoff JA, Ackland SP, Baldwin ML, Keane MA, McCluskey A. Invest New Drugs; 2002 Feb 15; 20(1):1-11. PubMed ID: 12003183 [Abstract] [Full Text] [Related]
8. Modulation of vinblastine cytotoxicity by dilantin (phenytoin) or the protein phosphatase inhibitor okadaic acid involves the potentiation of anti-mitotic effects and induction of apoptosis in human tumour cells. Kawamura KI, Grabowski D, Weizer K, Bukowski R, Ganapathi R. Br J Cancer; 1996 Jan 15; 73(2):183-8. PubMed ID: 8546904 [Abstract] [Full Text] [Related]
9. Okadaic acid inhibits a protein phosphatase activity involved in formation of the mitotic spindle of GH4 rat pituitary cells. Van Dolah FM, Ramsdell JS. J Cell Physiol; 1992 Jul 15; 152(1):190-8. PubMed ID: 1320037 [Abstract] [Full Text] [Related]
10. Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage. Blakemore LM, Boes C, Cordell R, Manson MM. Carcinogenesis; 2013 Feb 15; 34(2):351-60. PubMed ID: 23125222 [Abstract] [Full Text] [Related]
11. Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint. Foss KM, Robeson AC, Kornbluth S, Zhang L. Cell Cycle; 2016 Feb 15; 15(2):225-33. PubMed ID: 26652909 [Abstract] [Full Text] [Related]
12. Serine/threonine protein phosphatase inhibition enhances the effect of thymidylate synthase inhibition. Sakoff JA, Howitt IJ, Ackland SP, McCluskey A. Cancer Chemother Pharmacol; 2004 Mar 15; 53(3):225-32. PubMed ID: 14648018 [Abstract] [Full Text] [Related]
13. Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases. Matsuhashi A, Ohno T, Kimura M, Hara A, Saio M, Nagano A, Kawai G, Saitou M, Takigami I, Yamada K, Okano Y, Shimizu K. Curr Cancer Drug Targets; 2012 Jul 15; 12(6):625-39. PubMed ID: 22463590 [Abstract] [Full Text] [Related]
14. Vanadocenes as potent anti-proliferative agents disrupting mitotic spindle formation in cancer cells. Navara CS, Benyumov A, Vassilev A, Narla RK, Ghosh P, Uckun FM. Anticancer Drugs; 2001 Apr 15; 12(4):369-76. PubMed ID: 11335794 [Abstract] [Full Text] [Related]
15. The farnesyltransferase inhibitor, FTI-2153, blocks bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells. Crespo NC, Ohkanda J, Yen TJ, Hamilton AD, Sebti SM. J Biol Chem; 2001 May 11; 276(19):16161-7. PubMed ID: 11154688 [Abstract] [Full Text] [Related]
16. 2-methoxyestradiol induces cell cycle arrest and mitotic cell apoptosis in human vascular smooth muscle cells. Gui Y, Zheng XL. Hypertension; 2006 Feb 11; 47(2):271-80. PubMed ID: 16380515 [Abstract] [Full Text] [Related]
17. Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells. Holy JM. Mutat Res; 2002 Jun 27; 518(1):71-84. PubMed ID: 12063069 [Abstract] [Full Text] [Related]
18. Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress. Akhter S, Richie CT, Deng JM, Brey E, Zhang X, Patrick C, Behringer RR, Legerski RJ. Mol Cell Biol; 2004 Dec 27; 24(23):10448-55. PubMed ID: 15542852 [Abstract] [Full Text] [Related]