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Journal Abstract Search

198 related items for PubMed ID: 17139078

  • 1.
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  • 2. Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.
    Liu G, Xin Z, Pei Z, Hajduk PJ, Abad-Zapatero C, Hutchins CW, Zhao H, Lubben TH, Ballaron SJ, Haasch DL, Kaszubska W, Rondinone CM, Trevillyan JM, Jirousek MR.
    J Med Chem; 2003 Sep 25; 46(20):4232-5. PubMed ID: 13678400
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  • 3. MAPK-specific tyrosine phosphatases: new targets for drug discovery?
    Barr AJ, Knapp S.
    Trends Pharmacol Sci; 2006 Oct 25; 27(10):525-30. PubMed ID: 16919785
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  • 4. Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy.
    Szczepankiewicz BG, Liu G, Hajduk PJ, Abad-Zapatero C, Pei Z, Xin Z, Lubben TH, Trevillyan JM, Stashko MA, Ballaron SJ, Liang H, Huang F, Hutchins CW, Fesik SW, Jirousek MR.
    J Am Chem Soc; 2003 Apr 09; 125(14):4087-96. PubMed ID: 12670229
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  • 6. Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics.
    Combs AP, Yue EW, Bower M, Ala PJ, Wayland B, Douty B, Takvorian A, Polam P, Wasserman Z, Zhu W, Crawley ML, Pruitt J, Sparks R, Glass B, Modi D, McLaughlin E, Bostrom L, Li M, Galya L, Blom K, Hillman M, Gonneville L, Reid BG, Wei M, Becker-Pasha M, Klabe R, Huber R, Li Y, Hollis G, Burn TC, Wynn R, Liu P, Metcalf B.
    J Med Chem; 2005 Oct 20; 48(21):6544-8. PubMed ID: 16220970
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  • 8. Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B.
    Liu G, Szczepankiewicz BG, Pei Z, Janowick DA, Xin Z, Hajduk PJ, Abad-Zapatero C, Liang H, Hutchins CW, Fesik SW, Ballaron SJ, Stashko MA, Lubben T, Mika AK, Zinker BA, Trevillyan JM, Jirousek MR.
    J Med Chem; 2003 May 22; 46(11):2093-103. PubMed ID: 12747781
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  • 11. Importance of molecular computer modeling in anticancer drug development.
    Geromichalos GD.
    J BUON; 2007 Sep 22; 12 Suppl 1():S101-18. PubMed ID: 17935268
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  • 12. Inhibitors of protein tyrosine phosphatases: next-generation drugs?
    Bialy L, Waldmann H.
    Angew Chem Int Ed Engl; 2005 Jun 20; 44(25):3814-39. PubMed ID: 15900534
    [Abstract] [Full Text] [Related]

  • 13. High-throughput X-ray crystallography for drug discovery.
    Blundell TL, Patel S.
    Curr Opin Pharmacol; 2004 Oct 20; 4(5):490-6. PubMed ID: 15351354
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  • 15. Fragment-based lead discovery using X-ray crystallography.
    Hartshorn MJ, Murray CW, Cleasby A, Frederickson M, Tickle IJ, Jhoti H.
    J Med Chem; 2005 Jan 27; 48(2):403-13. PubMed ID: 15658854
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  • 18. Structure of human PRL-3, the phosphatase associated with cancer metastasis.
    Kim KA, Song JS, Jee J, Sheen MR, Lee C, Lee TG, Ro S, Cho JM, Lee W, Yamazaki T, Jeon YH, Cheong C.
    FEBS Lett; 2004 May 07; 565(1-3):181-7. PubMed ID: 15135076
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  • 19. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.
    Zhang S, Zhang ZY.
    Drug Discov Today; 2007 May 07; 12(9-10):373-81. PubMed ID: 17467573
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  • 20. Discovery of novel PRL-3 inhibitors based on the structure-based virtual screening.
    Park H, Jung SK, Jeong DG, Ryu SE, Kim SJ.
    Bioorg Med Chem Lett; 2008 Apr 01; 18(7):2250-5. PubMed ID: 18358718
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