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Journal Abstract Search

174 related items for PubMed ID: 17149879

  • 1. Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide.
    Murineddu G, Lazzari P, Ruiu S, Sanna A, Loriga G, Manca I, Falzoi M, Dessì C, Curzu MM, Chelucci G, Pani L, Pinna GA.
    J Med Chem; 2006 Dec 14; 49(25):7502-12. PubMed ID: 17149879
    [Abstract] [Full Text] [Related]

  • 2. Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide.
    Murineddu G, Ruiu S, Loriga G, Manca I, Lazzari P, Reali R, Pani L, Toma L, Pinna GA.
    J Med Chem; 2005 Nov 17; 48(23):7351-62. PubMed ID: 16279795
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  • 3. Tricyclic pyrazoles. Part 2: Synthesis and biological evaluation of novel 4,5-dihydro-1H-benzo[g]indazole-based ligands for cannabinoid receptors.
    Murineddu G, Ruiu S, Mussinu JM, Loriga G, Grella GE, Carai MA, Lazzari P, Pani L, Pinna GA.
    Bioorg Med Chem; 2005 May 02; 13(9):3309-20. PubMed ID: 15809166
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  • 4. Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties.
    Deiana V, Gómez-Cañas M, Pazos MR, Fernández-Ruiz J, Asproni B, Cichero E, Fossa P, Muñoz E, Deligia F, Murineddu G, García-Arencibia M, Pinna GA.
    Eur J Med Chem; 2016 Apr 13; 112():66-80. PubMed ID: 26890113
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  • 5. Synthesis and characterization of NESS 0327: a novel putative antagonist of the CB1 cannabinoid receptor.
    Ruiu S, Pinna GA, Marchese G, Mussinu JM, Saba P, Tambaro S, Casti P, Vargiu R, Pani L.
    J Pharmacol Exp Ther; 2003 Jul 13; 306(1):363-70. PubMed ID: 12663689
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  • 6. Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides.
    Silvestri R, Cascio MG, La Regina G, Piscitelli F, Lavecchia A, Brizzi A, Pasquini S, Botta M, Novellino E, Di Marzo V, Corelli F.
    J Med Chem; 2008 Mar 27; 51(6):1560-76. PubMed ID: 18293908
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  • 7. 1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice.
    Luongo L, Palazzo E, Tambaro S, Giordano C, Gatta L, Scafuro MA, Rossi FS, Lazzari P, Pani L, de Novellis V, Malcangio M, Maione S.
    Neurobiol Dis; 2010 Jan 27; 37(1):177-85. PubMed ID: 19804829
    [Abstract] [Full Text] [Related]

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  • 9. Oxadiazole-diarylpyrazole 4-carboxamides as cannabinoid CB1 receptor ligands.
    Lee SH, Seo HJ, Kim MJ, Kang SY, Song KS, Lee SH, Jung ME, Kim J, Lee J.
    Bioorg Med Chem Lett; 2009 Apr 01; 19(7):1899-902. PubMed ID: 19269817
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  • 12. Inverse agonist properties of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide HCl (SR141716A) and 1-(2-chlorophenyl)-4-cyano-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxyl ic acid phenylamide (CP-272871) for the CB(1) cannabinoid receptor.
    Meschler JP, Kraichely DM, Wilken GH, Howlett AC.
    Biochem Pharmacol; 2000 Nov 01; 60(9):1315-23. PubMed ID: 11008125
    [Abstract] [Full Text] [Related]

  • 13. A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives.
    Lazzari P, Distinto R, Manca I, Baillie G, Murineddu G, Pira M, Falzoi M, Sani M, Morales P, Ross R, Zanda M, Jagerovic N, Pinna GA.
    Eur J Med Chem; 2016 Oct 04; 121():194-208. PubMed ID: 27240274
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  • 14. Discovery of 1-(2,4-dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophen-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist.
    Hung MS, Chang CP, Li TC, Yeh TK, Song JS, Lin Y, Wu CH, Kuo PC, Amancha PK, Wong YC, Hsiao WC, Chao YS, Shia KS.
    ChemMedChem; 2010 Sep 03; 5(9):1439-43. PubMed ID: 20652930
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  • 17. 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands.
    Piscitelli F, Ligresti A, La Regina G, Gatti V, Brizzi A, Pasquini S, Allarà M, Carai MA, Novellino E, Colombo G, Di Marzo V, Corelli F, Silvestri R.
    Eur J Med Chem; 2011 Nov 03; 46(11):5641-53. PubMed ID: 21996466
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  • 18. Synthesis of [O-methyl-11C]1-(2-chlorophenyl)-5-(4-methoxyphenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide: a potential PET ligand for CB1 receptors.
    Kumar JS, Prabhakaran J, Arango V, Parsey RV, Underwood MD, Simpson NR, Kassir SA, Majo VJ, Van Heertum RL, Mann JJ.
    Bioorg Med Chem Lett; 2004 May 17; 14(10):2393-6. PubMed ID: 15109619
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  • 20. Synthesis and structure-activity relationship of 1,2,4-triazole-containing diarylpyrazolyl carboxamide as CB1 cannabinoid receptor-ligand.
    Seo HJ, Kim MJ, Lee SH, Lee SH, Jung ME, Kim MS, Ahn K, Kim J, Lee J.
    Bioorg Med Chem; 2010 Feb 17; 18(3):1149-62. PubMed ID: 20045337
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