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Journal Abstract Search

356 related items for PubMed ID: 17150972

  • 1. Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities.
    Ong MM, Latchoumycandane C, Boelsterli UA.
    Toxicol Sci; 2007 May; 97(1):205-13. PubMed ID: 17150972
    [Abstract] [Full Text] [Related]

  • 2. Troglitazone hepatotoxicity: are we getting closer to understanding idiosyncratic liver injury?
    Jaeschke H.
    Toxicol Sci; 2007 May; 97(1):1-3. PubMed ID: 17575588
    [No Abstract] [Full Text] [Related]

  • 3. Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2(+/-) mice: two-stage oxidative injury.
    Lee YH, Chung MC, Lin Q, Boelsterli UA.
    Toxicol Appl Pharmacol; 2008 Aug 15; 231(1):43-51. PubMed ID: 18495193
    [Abstract] [Full Text] [Related]

  • 4. Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2(+/-) mice.
    Ong MM, Wang AS, Leow KY, Khoo YM, Boelsterli UA.
    Free Radic Biol Med; 2006 Feb 01; 40(3):420-9. PubMed ID: 16443156
    [Abstract] [Full Text] [Related]

  • 5. The mitochondrial superoxide/thioredoxin-2/Ask1 signaling pathway is critically involved in troglitazone-induced cell injury to human hepatocytes.
    Lim PL, Liu J, Go ML, Boelsterli UA.
    Toxicol Sci; 2008 Feb 01; 101(2):341-9. PubMed ID: 17975114
    [Abstract] [Full Text] [Related]

  • 6. Integrative toxicoproteomics implicates impaired mitochondrial glutathione import as an off-target effect of troglitazone.
    Lee YH, Goh WW, Ng CK, Raida M, Wong L, Lin Q, Boelsterli UA, Chung MC.
    J Proteome Res; 2013 Jun 07; 12(6):2933-45. PubMed ID: 23659346
    [Abstract] [Full Text] [Related]

  • 7. Increased susceptibility to troglitazone-induced mitochondrial permeability transition in type 2 diabetes mellitus model rat.
    Segawa M, Sekine S, Sato T, Ito K.
    J Toxicol Sci; 2018 Jun 07; 43(5):339-351. PubMed ID: 29743445
    [Abstract] [Full Text] [Related]

  • 8. Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity.
    Kashimshetty R, Desai VG, Kale VM, Lee T, Moland CL, Branham WS, New LS, Chan EC, Younis H, Boelsterli UA.
    Toxicol Appl Pharmacol; 2009 Jul 15; 238(2):150-9. PubMed ID: 19442681
    [Abstract] [Full Text] [Related]

  • 9. Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen.
    Fujimoto K, Kumagai K, Ito K, Arakawa S, Ando Y, Oda S, Yamoto T, Manabe S.
    Toxicol Pathol; 2009 Feb 15; 37(2):193-200. PubMed ID: 19332662
    [Abstract] [Full Text] [Related]

  • 10. Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates.
    Larosche I, Choumar A, Fromenty B, Lettéron P, Abbey-Toby A, Van Remmen H, Epstein CJ, Richardson A, Feldmann G, Pessayre D, Mansouri A.
    Toxicol Appl Pharmacol; 2009 Feb 01; 234(3):326-38. PubMed ID: 19063909
    [Abstract] [Full Text] [Related]

  • 11. Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones.
    Masubuchi Y, Kano S, Horie T.
    Toxicology; 2006 May 15; 222(3):233-9. PubMed ID: 16621215
    [Abstract] [Full Text] [Related]

  • 12. Trovafloxacin, a fluoroquinolone antibiotic with hepatotoxic potential, causes mitochondrial peroxynitrite stress in a mouse model of underlying mitochondrial dysfunction.
    Hsiao CJ, Younis H, Boelsterli UA.
    Chem Biol Interact; 2010 Oct 06; 188(1):204-13. PubMed ID: 20655887
    [Abstract] [Full Text] [Related]

  • 13. Chimeric mice with a humanized liver as an animal model of troglitazone-induced liver injury.
    Kakuni M, Morita M, Matsuo K, Katoh Y, Nakajima M, Tateno C, Yokoi T.
    Toxicol Lett; 2012 Oct 02; 214(1):9-18. PubMed ID: 22902350
    [Abstract] [Full Text] [Related]

  • 14. Multiple mechanisms underlying troglitazone-induced mitochondrial permeability transition.
    Okuda T, Norioka M, Shitara Y, Horie T.
    Toxicol Appl Pharmacol; 2010 Nov 01; 248(3):242-8. PubMed ID: 20709092
    [Abstract] [Full Text] [Related]

  • 15. The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity.
    Ramachandran A, Lebofsky M, Weinman SA, Jaeschke H.
    Toxicol Appl Pharmacol; 2011 Mar 15; 251(3):226-33. PubMed ID: 21241727
    [Abstract] [Full Text] [Related]

  • 16. Troglitazone.
    Yokoi T.
    Handb Exp Pharmacol; 2010 Mar 15; (196):419-35. PubMed ID: 20020270
    [Abstract] [Full Text] [Related]

  • 17. Usefulness of in vitro combination assays of mitochondrial dysfunction and apoptosis for the estimation of potential risk of idiosyncratic drug induced liver injury.
    Goda K, Takahashi T, Kobayashi A, Shoda T, Kuno H, Sugai S.
    J Toxicol Sci; 2016 Mar 15; 41(5):605-15. PubMed ID: 27665770
    [Abstract] [Full Text] [Related]

  • 18. Mitochondrial and liver oxidative stress alterations induced by N-butyl-N-(4-hydroxybutyl)nitrosamine: relevance for hepatotoxicity.
    Oliveira MM, Teixeira JC, Vasconcelos-Nóbrega C, Felix LM, Sardão VA, Colaço AA, Oliveira PA, Peixoto FP.
    J Appl Toxicol; 2013 Jun 15; 33(6):434-43. PubMed ID: 22095756
    [Abstract] [Full Text] [Related]

  • 19. Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity.
    Nozawa T, Sugiura S, Nakajima M, Goto A, Yokoi T, Nezu J, Tsuji A, Tamai I.
    Drug Metab Dispos; 2004 Mar 15; 32(3):291-4. PubMed ID: 14977862
    [Abstract] [Full Text] [Related]

  • 20. Characterizing the mechanism of thiazolidinedione-induced hepatotoxicity: An in vitro model in mitochondria.
    Hu D, Wu CQ, Li ZJ, Liu Y, Fan X, Wang QJ, Ding RG.
    Toxicol Appl Pharmacol; 2015 Apr 15; 284(2):134-41. PubMed ID: 25727309
    [Abstract] [Full Text] [Related]

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