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Journal Abstract Search

76 related items for PubMed ID: 17154517

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  • 3. Synthesis and structure-activity relationships of a novel series of tricyclic dihydropyridine-based KATP openers that potently inhibit bladder contractions in vitro.
    Carroll WA, Agrios KA, Altenbach RJ, Buckner SA, Chen Y, Coghlan MJ, Daza AV, Drizin I, Gopalakrishnan M, Henry RF, Kort ME, Kym PR, Milicic I, Smith JC, Tang R, Turner SC, Whiteaker KL, Zhang H, Sullivan JP.
    J Med Chem; 2004 Jun 03; 47(12):3180-92. PubMed ID: 15163197
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  • 5. (-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficacious in suppressing urinary bladder contractions. II. in vivo characterization.
    Brune ME, Fey TA, Brioni JD, Sullivan JP, Williams M, Carroll WA, Coghlan MJ, Gopalakrishnan M.
    J Pharmacol Exp Ther; 2002 Oct 03; 303(1):387-94. PubMed ID: 12235275
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  • 6. Structure-activity studies of novel cyanoguanidine ATP-sensitive potassium channel openers for the treatment of overactive bladder.
    Perez-Medrano A, Brune ME, Buckner SA, Coghlan MJ, Fey TA, Gopalakrishnan M, Gregg RJ, Kort ME, Scott VE, Sullivan JP, Whiteaker KL, Carroll WA.
    J Med Chem; 2007 Nov 29; 50(24):6265-73. PubMed ID: 17973362
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  • 7. Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives.
    Braña MF, Gradillas A, Gómez A, Acero N, Llinares F, Muñoz-Mingarro D, Abradelo C, Rey-Stolle F, Yuste M, Campos J, Gallo MA, Espinosa A.
    J Med Chem; 2004 Apr 22; 47(9):2236-42. PubMed ID: 15084122
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  • 8. Characterization of a novel ATP-sensitive K+ channel opener, A-251179, on urinary bladder relaxation and cystometric parameters.
    Shieh CC, Brune ME, Buckner SA, Whiteaker KL, Molinari EJ, Milicic IA, Fabiyi AC, Daza A, Brioni JD, Carroll WA, Matsushita K, Yamada M, Kurachi Y, Gopalakrishnan M.
    Br J Pharmacol; 2007 Jun 22; 151(4):467-75. PubMed ID: 17435796
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  • 9. [125I]A-312110, a novel high-affinity 1,4-dihydropyridine ATP-sensitive K+ channel opener: characterization and pharmacology of binding.
    Davis-Taber R, Molinari EJ, Altenbach RJ, Whiteaker KL, Shieh CC, Rotert G, Buckner SA, Malysz J, Milicic I, McDermott JS, Gintant GA, Coghlan MJ, Carroll WA, Scott VE, Gopalakrishnan M.
    Mol Pharmacol; 2003 Jul 22; 64(1):143-53. PubMed ID: 12815170
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  • 10. Spontaneous contractions of the pig urinary bladder: the effect of ATP-sensitive potassium channels and the role of the mucosa.
    Akino H, Chapple CR, McKay N, Cross RL, Murakami S, Yokoyama O, Chess-Williams R, Sellers DJ.
    BJU Int; 2008 Nov 22; 102(9):1168-74. PubMed ID: 18647302
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  • 11. Discovery and structure-activity relationships of a novel series of benzopyran-based K(ATP) openers for urge urinary incontinence.
    Zhang X, Qiu Y, Li X, Bhattacharjee S, Woods M, Kraft P, Lundeen SG, Sui Z.
    Bioorg Med Chem; 2009 Jan 15; 17(2):855-66. PubMed ID: 19101153
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  • 13. Pharmacological characterization of the novel dihydropyridine potassium channel opener, (9R)-9-(3-iodo-4-methylphenyl)-5,9-dihydro-3H-furo[3,4-b]pyrano[4,3-e]pyridine-1,8(4H,7H)-dione (A-325100), and the regulation of cardiovascular function in conscious and anesthetized beagle dogs.
    Fryer RM, Rakestraw PA, Preusser LC, Brune ME, Carroll WA, Buckner SA, Shieh CC, King LL, Marsh KC, Gopalakrishnan M, Cox BF, Reinhart GA.
    J Cardiovasc Pharmacol; 2005 Aug 15; 46(2):232-40. PubMed ID: 16044036
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  • 14. N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: KATP potassium channel openers. Modifications on the western region.
    Ohnmacht CJ, Russell K, Empfield JR, Frank CA, Gibson KH, Mayhugh DR, McLaren FM, Shapiro HS, Brown FJ, Trainor DA, Ceccarelli C, Lin MM, Masek BB, Forst JM, Harris RJ, Hulsizer JM, Lewis JJ, Silverman SM, Smith RW, Warwick PJ, Kau ST, Chun AL, Grant TL, Howe BB, Neilson KL.
    J Med Chem; 1996 Nov 08; 39(23):4592-601. PubMed ID: 8917648
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  • 16. (-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637), a novel ATP-sensitive potassium channel opener: hemodynamic comparison to ZD-6169, WAY-133537, and nifedipine in the anesthetized canine.
    Fryer RM, Preusser LC, Calzadilla SV, Hu Y, Xu H, Marsh KC, Cox BF, Lin CT, Gopalakrishnan M, Reinhart GA.
    J Cardiovasc Pharmacol; 2004 Aug 08; 44(2):137-47. PubMed ID: 15243293
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  • 18. In vitro and in vivo characterization of a novel naphthylamide ATP-sensitive K+ channel opener, A-151892.
    Gopalakrishnan M, Buckner SA, Shieh CC, Fey T, Fabiyi A, Whiteaker KL, Davis-Taber R, Milicic I, Daza AV, Scott VE, Castle NA, Printzenhoff D, London B, Turner SC, Carroll WA, Sullivan JP, Coghlan MJ, Brune ME.
    Br J Pharmacol; 2004 Sep 08; 143(1):81-90. PubMed ID: 15302680
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  • 19. Inhibitory effects of different ATP-sensitive potassium channel openers on electrically generated and carbachol-induced contractions of porcine and human detrusor muscle.
    Badawi JK, Ding A, Bross S.
    Fundam Clin Pharmacol; 2008 Feb 08; 22(1):75-86. PubMed ID: 18251724
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