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Journal Abstract Search

176 related items for PubMed ID: 17156576

  • 1. Mechanisms of serpin dysfunction in disease.
    Kaiserman D, Whisstock JC, Bird PI.
    Expert Rev Mol Med; 2006 Dec 11; 8(31):1-19. PubMed ID: 17156576
    [Abstract] [Full Text] [Related]

  • 2. Familial conformational diseases and dementias.
    Crowther DC.
    Hum Mutat; 2002 Jul 11; 20(1):1-14. PubMed ID: 12112652
    [Abstract] [Full Text] [Related]

  • 3. The role of strand 1 of the C beta-sheet in the structure and function of alpha(1)-antitrypsin.
    Bottomley SP, Lawrenson ID, Tew D, Dai W, Whisstock JC, Pike RN.
    Protein Sci; 2001 Dec 11; 10(12):2518-24. PubMed ID: 11714919
    [Abstract] [Full Text] [Related]

  • 4. Hypersensitive mousetraps, alpha1-antitrypsin deficiency and dementia.
    Lomas DA, Lourbakos A, Cumming SA, Belorgey D.
    Biochem Soc Trans; 2002 Apr 11; 30(2):89-92. PubMed ID: 12023831
    [Abstract] [Full Text] [Related]

  • 5. Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies.
    Lomas DA, Belorgey D, Mallya M, Onda M, Kinghorn KJ, Sharp LK, Phillips RL, Page R, Crowther DC, Miranda E.
    Front Biosci; 2004 Sep 01; 9():2873-91. PubMed ID: 15353322
    [Abstract] [Full Text] [Related]

  • 6. Kinetic instability of the serpin Z alpha1-antitrypsin promotes aggregation.
    Knaupp AS, Levina V, Robertson AL, Pearce MC, Bottomley SP.
    J Mol Biol; 2010 Feb 19; 396(2):375-83. PubMed ID: 19944704
    [Abstract] [Full Text] [Related]

  • 7. Role of Lys335 in the metastability and function of inhibitory serpins.
    Im H, Yu MH.
    Protein Sci; 2000 May 19; 9(5):934-41. PubMed ID: 10850803
    [Abstract] [Full Text] [Related]

  • 8. Reversible inactivation of serpins at acidic pH.
    Boudier C, Bousquet JA, Schauinger S, Michels B, Bieth JG.
    Arch Biochem Biophys; 2007 Oct 15; 466(2):155-63. PubMed ID: 17765197
    [Abstract] [Full Text] [Related]

  • 9. Alpha1-antitrypsin deficiency--a model for conformational diseases.
    Carrell RW, Lomas DA.
    N Engl J Med; 2002 Jan 03; 346(1):45-53. PubMed ID: 11778003
    [No Abstract] [Full Text] [Related]

  • 10. Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases.
    Dementiev A, Simonovic M, Volz K, Gettins PG.
    J Biol Chem; 2003 Sep 26; 278(39):37881-7. PubMed ID: 12860985
    [Abstract] [Full Text] [Related]

  • 11. Alpha 1-antitrypsin polymerisation can occur by both loop A and C sheet mechanisms.
    Bottomley SP, Hopkins PC, Whisstock JC.
    Biochem Biophys Res Commun; 1998 Oct 09; 251(1):1-5. PubMed ID: 9790897
    [Abstract] [Full Text] [Related]

  • 12. Introduction of a mutation in the shutter region of antithrombin (Phe77 --> Leu) increases affinity for heparin and decreases thermal stability.
    Quinsey NS, Fitton HL, Coughlin P, Whisstock JC, Dafforn TR, Carrell RW, Bottomley SP, Pike RN.
    Biochemistry; 2003 Sep 02; 42(34):10169-73. PubMed ID: 12939144
    [Abstract] [Full Text] [Related]

  • 13. Cell toxicity and conformational disease.
    Carrell RW.
    Trends Cell Biol; 2005 Nov 02; 15(11):574-80. PubMed ID: 16202603
    [Abstract] [Full Text] [Related]

  • 14. Osmolytes as modulators of conformational changes in serpins.
    Chow MK, Devlin GL, Bottomley SP.
    Biol Chem; 2001 Nov 02; 382(11):1593-9. PubMed ID: 11767949
    [Abstract] [Full Text] [Related]

  • 15. Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.
    Crowther DC, Belorgey D, Miranda E, Kinghorn KJ, Sharp LK, Lomas DA.
    Eur J Hum Genet; 2004 Mar 02; 12(3):167-72. PubMed ID: 14694355
    [Abstract] [Full Text] [Related]

  • 16. Viscous drag as the source of active site perturbation during protease translocation: insights into how inhibitory processes are controlled by serpin metastability.
    Shin JS, Yu MH.
    J Mol Biol; 2006 Jun 02; 359(2):378-89. PubMed ID: 16626735
    [Abstract] [Full Text] [Related]

  • 17. What do dysfunctional serpins tell us about molecular mobility and disease?
    Stein PE, Carrell RW.
    Nat Struct Biol; 1995 Feb 02; 2(2):96-113. PubMed ID: 7749926
    [Abstract] [Full Text] [Related]

  • 18. Factors with conformational effects on haemostatic serpins: implications in thrombosis.
    Hernández-Espinosa D, Ordóñez A, Vicente V, Corral J.
    Thromb Haemost; 2007 Sep 02; 98(3):557-63. PubMed ID: 17849043
    [Abstract] [Full Text] [Related]

  • 19. The effect of the Glu342Lys mutation in alpha1-antitrypsin on its structure, studied by molecular modelling methods.
    Jezierski G, Pasenkiewicz-Gierula M.
    Acta Biochim Pol; 2001 Sep 02; 48(1):65-75. PubMed ID: 11440184
    [Abstract] [Full Text] [Related]

  • 20. Serpins: the uncut version.
    Goldsmith EJ, Mottonen J.
    Structure; 1994 Apr 15; 2(4):241-4. PubMed ID: 8087550
    [Abstract] [Full Text] [Related]

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