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Journal Abstract Search

234 related items for PubMed ID: 17157019

  • 1. Design and synthesis of oxime ethers of alpha-acyl-beta-phenylpropanoic acids as PPAR dual agonists.
    Oon Han H, Kim SH, Kim KH, Hur GC, Joo Yim H, Chung HK, Ho Woo S, Dong Koo K, Lee CS, Sung Koh J, Kim GT.
    Bioorg Med Chem Lett; 2007 Feb 15; 17(4):937-41. PubMed ID: 17157019
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  • 2. Revisiting glitazars: thiophene substituted oxazole containing α-ethoxy phenylpropanoic acid derivatives as highly potent PPARα/γ dual agonists devoid of adverse effects in rodents.
    Raval P, Jain M, Goswami A, Basu S, Gite A, Godha A, Pingali H, Raval S, Giri S, Suthar D, Shah M, Patel P.
    Bioorg Med Chem Lett; 2011 May 15; 21(10):3103-9. PubMed ID: 21450468
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  • 4. Synthesis and evaluation of azaindole-alpha-alkyloxyphenylpropionic acid analogues as PPARalpha/gamma agonists.
    Cai Z, Feng J, Guo Y, Li P, Shen Z, Chu F, Guo Z.
    Bioorg Med Chem; 2006 Feb 01; 14(3):866-74. PubMed ID: 16249089
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  • 6. Pyridine-2-propanoic acids: Discovery of dual PPARalpha/gamma agonists as antidiabetic agents.
    Humphries PS, Almaden JV, Barnum SJ, Carlson TJ, Do QQ, Fraser JD, Hess M, Kim YH, Ogilvie KM, Sun S.
    Bioorg Med Chem Lett; 2006 Dec 01; 16(23):6116-9. PubMed ID: 16979341
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  • 8. Synthesis and anti-diabetic activity of (RS)-2-ethoxy-3-{4-[2-(4-trifluoro-methanesulfonyloxy-phenyl)-ethoxy]-phenyl}-propionic acid.
    Cai ZF, Liu Q, Li PP, Guo ZR, Shen ZF.
    Acta Pharmacol Sin; 2006 May 01; 27(5):597-602. PubMed ID: 16626515
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  • 10. Indanylacetic acid derivatives carrying aryl-pyridyl and aryl-pyrimidinyl tail groups--new classes of PPAR gamma/delta and PPAR alpha/gamma/delta agonists.
    Cantin LD, Liang S, Ogutu H, Iwuagwu CI, Boakye K, Bullock WH, Burns M, Clark R, Claus T, delaCruz FE, Daly M, Ehrgott FJ, Johnson JS, Keiper C, Livingston JN, Schoenleber RW, Shapiro J, Town C, Yang L, Tsutsumi M, Ma X.
    Bioorg Med Chem Lett; 2007 Feb 15; 17(4):1056-61. PubMed ID: 17157013
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  • 13. Design and synthesis of a novel class of dual PPARgamma/delta agonists.
    Gonzalez IC, Lamar J, Iradier F, Xu Y, Winneroski LL, York J, Yumibe N, Zink R, Montrose-Rafizadeh C, Etgen GJ, Broderick CL, Oldham BA, Mantlo N.
    Bioorg Med Chem Lett; 2007 Feb 15; 17(4):1052-5. PubMed ID: 17129725
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  • 15. Antidiabetic and hypolipidemic potential of DRF 2519--a dual activator of PPAR-alpha and PPAR-gamma.
    Chakrabarti R, Misra P, Vikramadithyan RK, Premkumar M, Hiriyan J, Datla SR, Damarla RK, Suresh J, Rajagopalan R.
    Eur J Pharmacol; 2004 May 03; 491(2-3):195-206. PubMed ID: 15140637
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  • 16. Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies.
    Casimiro-Garcia A, Bigge CF, Davis JA, Padalino T, Pulaski J, Ohren JF, McConnell P, Kane CD, Royer LJ, Stevens KA, Auerbach BJ, Collard WT, McGregor C, Fakhoury SA, Schaum RP, Zhou H.
    Bioorg Med Chem; 2008 May 01; 16(9):4883-907. PubMed ID: 18394907
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  • 17. Design, synthesis and evaluation of novel zwitterionic compounds as PPARα/γ dual agonists (1).
    Shibata Y, Kagechika K, Yamaguchi M, Kubo H, Usui H.
    Bioorg Med Chem Lett; 2012 Dec 01; 22(23):7075-9. PubMed ID: 23084275
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  • 18. PAR-5359, a well-balanced PPARalpha/gamma dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo.
    Kim MK, Chae YN, Son MH, Kim SH, Kim JK, Moon HS, Park CS, Bae MH, Kim E, Han T, Choi HH, Shin YA, Ahn BN, Lee CH, Lim JI, Shin CY.
    Eur J Pharmacol; 2008 Oct 24; 595(1-3):119-25. PubMed ID: 18727927
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  • 19. Design and synthesis of novel oxazole containing 1,3-dioxane-2-carboxylic acid derivatives as PPAR alpha/gamma dual agonists.
    Pingali H, Jain M, Shah S, Makadia P, Zaware P, Goel A, Patel M, Giri S, Patel H, Patel P.
    Bioorg Med Chem; 2008 Aug 01; 16(15):7117-27. PubMed ID: 18625559
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