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543 related items for PubMed ID: 17158963

  • 1. Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.
    Shreeram S, Hee WK, Demidov ON, Kek C, Yamaguchi H, Fornace AJ, Anderson CW, Appella E, Bulavin DV.
    J Exp Med; 2006 Dec 25; 203(13):2793-9. PubMed ID: 17158963
    [Abstract] [Full Text] [Related]

  • 2. Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.
    Yoda A, Toyoshima K, Watanabe Y, Onishi N, Hazaka Y, Tsukuda Y, Tsukada J, Kondo T, Tanaka Y, Minami Y.
    J Biol Chem; 2008 Jul 04; 283(27):18969-79. PubMed ID: 18482988
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  • 3. Wip1 phosphatase modulates ATM-dependent signaling pathways.
    Shreeram S, Demidov ON, Hee WK, Yamaguchi H, Onishi N, Kek C, Timofeev ON, Dudgeon C, Fornace AJ, Anderson CW, Minami Y, Appella E, Bulavin DV.
    Mol Cell; 2006 Sep 01; 23(5):757-64. PubMed ID: 16949371
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  • 4. Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis.
    Maclean KH, Dorsey FC, Cleveland JL, Kastan MB.
    J Clin Invest; 2008 Jan 01; 118(1):79-88. PubMed ID: 18097482
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  • 5. Overexpression of the wip1 gene abrogates the p38 MAPK/p53/Wip1 pathway and silences p16 expression in human breast cancers.
    Yu E, Ahn YS, Jang SJ, Kim MJ, Yoon HS, Gong G, Choi J.
    Breast Cancer Res Treat; 2007 Mar 01; 101(3):269-78. PubMed ID: 16897432
    [Abstract] [Full Text] [Related]

  • 6. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X, Ma O, Nguyen TA, Jones SN, Oren M, Donehower LA.
    Cancer Cell; 2007 Oct 01; 12(4):342-54. PubMed ID: 17936559
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  • 7. Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.
    Darlington Y, Nguyen TA, Moon SH, Herron A, Rao P, Zhu C, Lu X, Donehower LA.
    Oncogene; 2012 Mar 01; 31(9):1155-65. PubMed ID: 21765465
    [Abstract] [Full Text] [Related]

  • 8. Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D.
    Lu X, Nguyen TA, Donehower LA.
    Cell Cycle; 2005 Aug 01; 4(8):1060-4. PubMed ID: 15970689
    [Abstract] [Full Text] [Related]

  • 9. The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
    Reimann M, Loddenkemper C, Rudolph C, Schildhauer I, Teichmann B, Stein H, Schlegelberger B, Dörken B, Schmitt CA.
    Blood; 2007 Oct 15; 110(8):2996-3004. PubMed ID: 17562874
    [Abstract] [Full Text] [Related]

  • 10. The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases.
    Yamaguchi H, Durell SR, Chatterjee DK, Anderson CW, Appella E.
    Biochemistry; 2007 Nov 06; 46(44):12594-603. PubMed ID: 17939684
    [Abstract] [Full Text] [Related]

  • 11. Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.
    Sluss HK, Gannon H, Coles AH, Shen Q, Eischen CM, Jones SN.
    Mol Cancer Res; 2010 Feb 06; 8(2):216-22. PubMed ID: 20145032
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