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162 related items for PubMed ID: 17161371

  • 1. "Similarity trap" in protein-protein interactions could be carcinogenic: simulations of p53 core domain complexed with 53BP1 and BRCA1 BRCT domains.
    Liu J, Pan Y, Ma B, Nussinov R.
    Structure; 2006 Dec; 14(12):1811-21. PubMed ID: 17161371
    [Abstract] [Full Text] [Related]

  • 2. Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis.
    Ekblad CM, Friedler A, Veprintsev D, Weinberg RL, Itzhaki LS.
    Protein Sci; 2004 Mar; 13(3):617-25. PubMed ID: 14978302
    [Abstract] [Full Text] [Related]

  • 3. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure.
    Joo WS, Jeffrey PD, Cantor SB, Finnin MS, Livingston DM, Pavletich NP.
    Genes Dev; 2002 Mar 01; 16(5):583-93. PubMed ID: 11877378
    [Abstract] [Full Text] [Related]

  • 4. Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
    Derbyshire DJ, Basu BP, Serpell LC, Joo WS, Date T, Iwabuchi K, Doherty AJ.
    EMBO J; 2002 Jul 15; 21(14):3863-72. PubMed ID: 12110597
    [Abstract] [Full Text] [Related]

  • 5. Thermal and chemical denaturation of the BRCT functional module of human 53BP1.
    Thanassoulas A, Nomikos M, Theodoridou M, Stavros P, Mastellos D, Nounesis G.
    Int J Biol Macromol; 2011 Oct 01; 49(3):297-304. PubMed ID: 21600917
    [Abstract] [Full Text] [Related]

  • 6. Boundaries and physical characterization of a new domain shared between mammalian 53BP1 and yeast Rad9 checkpoint proteins.
    Alpha-Bazin B, Lorphelin A, Nozerand N, Charier G, Marchetti C, Bérenguer F, Couprie J, Gilquin B, Zinn-Justin S, Quéméneur E.
    Protein Sci; 2005 Jul 01; 14(7):1827-39. PubMed ID: 15987907
    [Abstract] [Full Text] [Related]

  • 7. Interactions between BRCT repeats and phosphoproteins: tangled up in two.
    Glover JN, Williams RS, Lee MS.
    Trends Biochem Sci; 2004 Nov 01; 29(11):579-85. PubMed ID: 15501676
    [Abstract] [Full Text] [Related]

  • 8. A structural bioinformatics approach to explore the interactions of P53 and BRCA1 gene products on ovarian and breast cancer.
    Parija S, Kumar A.
    Int J Bioinform Res Appl; 2011 Nov 01; 7(1):1-14. PubMed ID: 21441093
    [Abstract] [Full Text] [Related]

  • 9. The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter.
    Chai YL, Cui J, Shao N, Shyam E, Reddy P, Rao VN.
    Oncogene; 1999 Jan 07; 18(1):263-8. PubMed ID: 9926942
    [Abstract] [Full Text] [Related]

  • 10. The Tudor tandem of 53BP1: a new structural motif involved in DNA and RG-rich peptide binding.
    Charier G, Couprie J, Alpha-Bazin B, Meyer V, Quéméneur E, Guérois R, Callebaut I, Gilquin B, Zinn-Justin S.
    Structure; 2004 Sep 07; 12(9):1551-62. PubMed ID: 15341721
    [Abstract] [Full Text] [Related]

  • 11. Characterization of cancer-linked BRCA1-BRCT missense variants and their interaction with phosphoprotein targets.
    Drikos I, Nounesis G, Vorgias CE.
    Proteins; 2009 Nov 01; 77(2):464-76. PubMed ID: 19452558
    [Abstract] [Full Text] [Related]

  • 12. Cancer-related mutations in BRCA1-BRCT cause long-range structural changes in protein-protein binding sites: a molecular dynamics study.
    Gough CA, Gojobori T, Imanishi T.
    Proteins; 2007 Jan 01; 66(1):69-86. PubMed ID: 17063491
    [Abstract] [Full Text] [Related]

  • 13. Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif.
    Wu Q, Jubb H, Blundell TL.
    Prog Biophys Mol Biol; 2015 Mar 01; 117(2-3):143-148. PubMed ID: 25701377
    [Abstract] [Full Text] [Related]

  • 14. Primary structure-based function characterization of BRCT domain replicates in BRCA1.
    Chen Y, Borowicz S, Fackenthal J, Collart FR, Myatt E, Moy S, Babnigg G, Wilton R, Boernke WE, Schiffer M, Stevens FJ, Olopade OI.
    Biochem Biophys Res Commun; 2006 Jun 23; 345(1):188-96. PubMed ID: 16677609
    [Abstract] [Full Text] [Related]

  • 15. The 8-kDa dynein light chain binds to p53-binding protein 1 and mediates DNA damage-induced p53 nuclear accumulation.
    Lo KW, Kan HM, Chan LN, Xu WG, Wang KP, Wu Z, Sheng M, Zhang M.
    J Biol Chem; 2005 Mar 04; 280(9):8172-9. PubMed ID: 15611139
    [Abstract] [Full Text] [Related]

  • 16. Purification, crystallization and preliminary X-ray analysis of the BRCT domains of human 53BP1 bound to the p53 tumour suppressor.
    Derbyshire DJ, Basu BP, Date T, Iwabuchi K, Doherty AJ.
    Acta Crystallogr D Biol Crystallogr; 2002 Oct 04; 58(Pt 10 Pt 2):1826-9. PubMed ID: 12351827
    [Abstract] [Full Text] [Related]

  • 17. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.
    Bork P, Hofmann K, Bucher P, Neuwald AF, Altschul SF, Koonin EV.
    FASEB J; 1997 Jan 04; 11(1):68-76. PubMed ID: 9034168
    [Abstract] [Full Text] [Related]

  • 18. The BRCT domain is a phospho-protein binding domain.
    Yu X, Chini CC, He M, Mer G, Chen J.
    Science; 2003 Oct 24; 302(5645):639-42. PubMed ID: 14576433
    [Abstract] [Full Text] [Related]

  • 19. The tandem BRCT domain of 53BP1 is not required for its repair function.
    Ward I, Kim JE, Minn K, Chini CC, Mer G, Chen J.
    J Biol Chem; 2006 Dec 15; 281(50):38472-7. PubMed ID: 17043355
    [Abstract] [Full Text] [Related]

  • 20. A novel domain of BRCA1 interacts with p53 in breast cancer cells.
    Buck M.
    Cancer Lett; 2008 Sep 08; 268(1):137-45. PubMed ID: 18501503
    [Abstract] [Full Text] [Related]

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