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540 related items for PubMed ID: 17167421

  • 1. Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
    Jin R, Rummel A, Binz T, Brunger AT.
    Nature; 2006 Dec 21; 444(7122):1092-5. PubMed ID: 17167421
    [Abstract] [Full Text] [Related]

  • 2. Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
    Chai Q, Arndt JW, Dong M, Tepp WH, Johnson EA, Chapman ER, Stevens RC.
    Nature; 2006 Dec 21; 444(7122):1096-100. PubMed ID: 17167418
    [Abstract] [Full Text] [Related]

  • 3. Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity.
    Willjes G, Mahrhold S, Strotmeier J, Eichner T, Rummel A, Binz T.
    Biochemistry; 2013 Jun 04; 52(22):3930-8. PubMed ID: 23647335
    [Abstract] [Full Text] [Related]

  • 4. Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: increased therapeutic dosage and immunogenicity.
    Strotmeier J, Willjes G, Binz T, Rummel A.
    FEBS Lett; 2012 Feb 17; 586(4):310-3. PubMed ID: 22265973
    [Abstract] [Full Text] [Related]

  • 5. Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins.
    Peng L, Berntsson RP, Tepp WH, Pitkin RM, Johnson EA, Stenmark P, Dong M.
    J Cell Sci; 2012 Jul 01; 125(Pt 13):3233-42. PubMed ID: 22454523
    [Abstract] [Full Text] [Related]

  • 6. Structural biology: dangerous liaisons on neurons.
    Schiavo G.
    Nature; 2006 Dec 21; 444(7122):1019-20. PubMed ID: 17167419
    [No Abstract] [Full Text] [Related]

  • 7. Association of botulinum neurotoxin serotypes a and B with synaptic vesicle protein complexes.
    Baldwin MR, Barbieri JT.
    Biochemistry; 2007 Mar 20; 46(11):3200-10. PubMed ID: 17311420
    [Abstract] [Full Text] [Related]

  • 8. Crystal structures of botulinum neurotoxin DC in complex with its protein receptors synaptotagmin I and II.
    Berntsson RP, Peng L, Svensson LM, Dong M, Stenmark P.
    Structure; 2013 Sep 03; 21(9):1602-11. PubMed ID: 23932591
    [Abstract] [Full Text] [Related]

  • 9. Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept.
    Rummel A, Eichner T, Weil T, Karnath T, Gutcaits A, Mahrhold S, Sandhoff K, Proia RL, Acharya KR, Bigalke H, Binz T.
    Proc Natl Acad Sci U S A; 2007 Jan 02; 104(1):359-64. PubMed ID: 17185412
    [Abstract] [Full Text] [Related]

  • 10. Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
    Rummel A.
    Curr Top Microbiol Immunol; 2013 Jan 02; 364():61-90. PubMed ID: 23239349
    [Abstract] [Full Text] [Related]

  • 11. Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons.
    Dong M, Tepp WH, Liu H, Johnson EA, Chapman ER.
    J Cell Biol; 2007 Dec 31; 179(7):1511-22. PubMed ID: 18158333
    [Abstract] [Full Text] [Related]

  • 12. Gangliosides interact with synaptotagmin to form the high-affinity receptor complex for botulinum neurotoxin B.
    Flores A, Ramirez-Franco J, Desplantes R, Debreux K, Ferracci G, Wernert F, Blanchard MP, Maulet Y, Youssouf F, Sangiardi M, Iborra C, Popoff MR, Seagar M, Fantini J, Lévêque C, El Far O.
    Proc Natl Acad Sci U S A; 2019 Sep 03; 116(36):18098-18108. PubMed ID: 31431523
    [Abstract] [Full Text] [Related]

  • 13. Differential contribution of the residues in C-terminal half of the heavy chain of botulinum neurotoxin type B to its binding to the ganglioside GT1b and the synaptotagmin 2/GT1b complex.
    Kohda T, Ihara H, Seto Y, Tsutsuki H, Mukamoto M, Kozaki S.
    Microb Pathog; 2007 Sep 03; 42(2-3):72-9. PubMed ID: 17188834
    [Abstract] [Full Text] [Related]

  • 14.
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  • 15. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
    Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R.
    Biochem J; 2010 Oct 15; 431(2):207-16. PubMed ID: 20704566
    [Abstract] [Full Text] [Related]

  • 16. Structure of dual receptor binding to botulinum neurotoxin B.
    Berntsson RP, Peng L, Dong M, Stenmark P.
    Nat Commun; 2013 Oct 15; 4():2058. PubMed ID: 23807078
    [Abstract] [Full Text] [Related]

  • 17. Structure of botulinum neurotoxin type D light chain at 1.65 A resolution: repercussions for VAMP-2 substrate specificity.
    Arndt JW, Chai Q, Christian T, Stevens RC.
    Biochemistry; 2006 Mar 14; 45(10):3255-62. PubMed ID: 16519520
    [Abstract] [Full Text] [Related]

  • 18. Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.
    Rummel A, Karnath T, Henke T, Bigalke H, Binz T.
    J Biol Chem; 2004 Jul 16; 279(29):30865-70. PubMed ID: 15123599
    [Abstract] [Full Text] [Related]

  • 19. Ganglioside GT1b as a complementary receptor component for Clostridium botulinum neurotoxins.
    Kozaki S, Kamata Y, Watarai S, Nishiki T, Mochida S.
    Microb Pathog; 1998 Aug 16; 25(2):91-9. PubMed ID: 9712688
    [Abstract] [Full Text] [Related]

  • 20. A new neutralizing antibody against botulinum neurotoxin B recognizes the protein receptor binding sites for synaptotagmins II.
    Wang H, Li T, Shi J, Cai K, Hou X, Wang Q, Xiao L, Tu W, Liu H, Gao X.
    Microbes Infect; 2010 Nov 16; 12(12-13):1012-8. PubMed ID: 20650331
    [Abstract] [Full Text] [Related]

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