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161 related items for PubMed ID: 17168518

  • 1. Rescuing defective vesicular trafficking protects against alpha-synuclein toxicity in cellular and animal models of Parkinson's disease.
    Lashuel HA, Hirling H.
    ACS Chem Biol; 2006 Aug 22; 1(7):420-4. PubMed ID: 17168518
    [Abstract] [Full Text] [Related]

  • 2. Alpha-synuclein and Parkinson's disease: a proteomic view.
    Fasano M, Lopiano L.
    Expert Rev Proteomics; 2008 Apr 22; 5(2):239-48. PubMed ID: 18466054
    [Abstract] [Full Text] [Related]

  • 3. alpha-Synuclein, oxidative stress and apoptosis from the perspective of a yeast model of Parkinson's disease.
    Witt SN, Flower TR.
    FEMS Yeast Res; 2006 Dec 22; 6(8):1107-16. PubMed ID: 17156009
    [Abstract] [Full Text] [Related]

  • 4. alpha-Synuclein regulation of the dopaminergic transporter: a possible role in the pathogenesis of Parkinson's disease.
    Sidhu A, Wersinger C, Vernier P.
    FEBS Lett; 2004 May 07; 565(1-3):1-5. PubMed ID: 15135042
    [Abstract] [Full Text] [Related]

  • 5. Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models.
    Su LJ, Auluck PK, Outeiro TF, Yeger-Lotem E, Kritzer JA, Tardiff DF, Strathearn KE, Liu F, Cao S, Hamamichi S, Hill KJ, Caldwell KA, Bell GW, Fraenkel E, Cooper AA, Caldwell GA, McCaffery JM, Rochet JC, Lindquist S.
    Dis Model Mech; 2010 May 07; 3(3-4):194-208. PubMed ID: 20038714
    [Abstract] [Full Text] [Related]

  • 6. Acetaminophen attenuates dopamine neuron degeneration in animal models of Parkinson's disease.
    Locke CJ, Fox SA, Caldwell GA, Caldwell KA.
    Neurosci Lett; 2008 Jul 11; 439(2):129-33. PubMed ID: 18514411
    [Abstract] [Full Text] [Related]

  • 7. Controlling the mass action of alpha-synuclein in Parkinson's disease.
    Kim C, Lee SJ.
    J Neurochem; 2008 Oct 11; 107(2):303-16. PubMed ID: 18691382
    [Abstract] [Full Text] [Related]

  • 8. Impairment of microtubule-dependent trafficking by overexpression of alpha-synuclein.
    Lee HJ, Khoshaghideh F, Lee S, Lee SJ.
    Eur J Neurosci; 2006 Dec 11; 24(11):3153-62. PubMed ID: 17156376
    [Abstract] [Full Text] [Related]

  • 9. The degeneration of dopamine neurons in Parkinson's disease: insights from embryology and evolution of the mesostriatocortical system.
    Vernier P, Moret F, Callier S, Snapyan M, Wersinger C, Sidhu A.
    Ann N Y Acad Sci; 2004 Dec 11; 1035():231-49. PubMed ID: 15681811
    [Abstract] [Full Text] [Related]

  • 10. The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis.
    Gitler AD, Bevis BJ, Shorter J, Strathearn KE, Hamamichi S, Su LJ, Caldwell KA, Caldwell GA, Rochet JC, McCaffery JM, Barlowe C, Lindquist S.
    Proc Natl Acad Sci U S A; 2008 Jan 08; 105(1):145-50. PubMed ID: 18162536
    [Abstract] [Full Text] [Related]

  • 11. Does cellular iron dysregulation play a causative role in Parkinson's disease?
    Kaur D, Andersen J.
    Ageing Res Rev; 2004 Jul 08; 3(3):327-43. PubMed ID: 15231240
    [Abstract] [Full Text] [Related]

  • 12. The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease.
    Lee FK, Wong AK, Lee YW, Wan OW, Chan HY, Chung KK.
    J Neurochem; 2009 Jul 08; 110(1):208-19. PubMed ID: 19457126
    [Abstract] [Full Text] [Related]

  • 13. Synuclein, dopamine and oxidative stress: co-conspirators in Parkinson's disease?
    Maguire-Zeiss KA, Short DW, Federoff HJ.
    Brain Res Mol Brain Res; 2005 Mar 24; 134(1):18-23. PubMed ID: 15790526
    [Abstract] [Full Text] [Related]

  • 14. Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein.
    Park SS, Schulz EM, Lee D.
    Eur J Neurosci; 2007 Dec 24; 26(11):3104-12. PubMed ID: 18005066
    [Abstract] [Full Text] [Related]

  • 15. Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models.
    Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, Labaer J, Rochet JC, Bonini NM, Lindquist S.
    Science; 2006 Jul 21; 313(5785):324-8. PubMed ID: 16794039
    [Abstract] [Full Text] [Related]

  • 16. Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease.
    Azeredo da Silveira S, Schneider BL, Cifuentes-Diaz C, Sage D, Abbas-Terki T, Iwatsubo T, Unser M, Aebischer P.
    Hum Mol Genet; 2009 Mar 01; 18(5):872-87. PubMed ID: 19074459
    [Abstract] [Full Text] [Related]

  • 17. Aggregation-defective alpha-synuclein mutants inhibit the fibrillation of Parkinson's disease-linked alpha-synuclein variants.
    Koo HJ, Choi MY, Im H.
    Biochem Biophys Res Commun; 2009 Aug 14; 386(1):165-9. PubMed ID: 19501571
    [Abstract] [Full Text] [Related]

  • 18. A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides.
    Gallardo G, Schlüter OM, Südhof TC.
    Nat Neurosci; 2008 Mar 14; 11(3):301-8. PubMed ID: 18297066
    [Abstract] [Full Text] [Related]

  • 19. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.
    Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG.
    Science; 2007 Jul 27; 317(5837):516-9. PubMed ID: 17588900
    [Abstract] [Full Text] [Related]

  • 20. The role of alpha-synuclein in both neuroprotection and neurodegeneration.
    Sidhu A, Wersinger C, Moussa CE, Vernier P.
    Ann N Y Acad Sci; 2004 Dec 27; 1035():250-70. PubMed ID: 15681812
    [Abstract] [Full Text] [Related]

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