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388 related items for PubMed ID: 17170118
1. Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNA. Sun L, Stoecklin G, Van Way S, Hinkovska-Galcheva V, Guo RF, Anderson P, Shanley TP. J Biol Chem; 2007 Feb 09; 282(6):3766-77. PubMed ID: 17170118 [Abstract] [Full Text] [Related]
2. Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element. Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. Mol Cell Biol; 2006 Mar 09; 26(6):2399-407. PubMed ID: 16508014 [Abstract] [Full Text] [Related]
3. Tristetraprolin regulates TNF TNF-alpha mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways. Deleault KM, Skinner SJ, Brooks SA. Mol Immunol; 2008 Jan 09; 45(1):13-24. PubMed ID: 17606294 [Abstract] [Full Text] [Related]
4. Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability. Mahtani KR, Brook M, Dean JL, Sully G, Saklatvala J, Clark AR. Mol Cell Biol; 2001 Oct 09; 21(19):6461-9. PubMed ID: 11533235 [Abstract] [Full Text] [Related]
5. p38 MAPK/PP2Acα/TTP pathway on the connection of TNF-α and caspases activation on hydroquinone-induced apoptosis. Liu WH, Chou WM, Chang LS. Carcinogenesis; 2013 Apr 09; 34(4):818-27. PubMed ID: 23288922 [Abstract] [Full Text] [Related]
6. Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism. Zhao XK, Che P, Cheng ML, Zhang Q, Mu M, Li H, Luo Y, Liang YD, Luo XH, Gao CQ, Jackson PL, Wells JM, Zhou Y, Hu M, Cai G, Thannickal VJ, Steele C, Blalock JE, Han X, Chen CY, Ding Q. PLoS One; 2016 Apr 09; 11(12):e0167451. PubMed ID: 27911957 [Abstract] [Full Text] [Related]
7. LPS-induced production of TNF-α and IL-6 in mast cells is dependent on p38 but independent of TTP. Hochdörfer T, Tiedje C, Stumpo DJ, Blackshear PJ, Gaestel M, Huber M. Cell Signal; 2013 Jun 09; 25(6):1339-47. PubMed ID: 23499908 [Abstract] [Full Text] [Related]
8. Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability. Frasca D, Romero M, Landin AM, Diaz A, Riley RL, Blomberg BB. Mech Ageing Dev; 2010 May 09; 131(5):306-14. PubMed ID: 20219523 [Abstract] [Full Text] [Related]
9. Inhibition of tristetraprolin deadenylation by poly(A) binding protein. Rowlett RM, Chrestensen CA, Schroeder MJ, Harp MG, Pelo JW, Shabanowitz J, DeRose R, Hunt DF, Sturgill TW, Worthington MT. Am J Physiol Gastrointest Liver Physiol; 2008 Sep 09; 295(3):G421-30. PubMed ID: 18467502 [Abstract] [Full Text] [Related]
10. A combination of hypoxia and lipopolysaccharide activates tristetraprolin to destabilize proinflammatory mRNAs such as tumor necrosis factor-alpha. Werno C, Schmid T, Schnitzer SE, Peters K, Milke L, Brüne B. Am J Pathol; 2010 Sep 09; 177(3):1104-12. PubMed ID: 20639458 [Abstract] [Full Text] [Related]
11. MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment. Marchese FP, Aubareda A, Tudor C, Saklatvala J, Clark AR, Dean JL. J Biol Chem; 2010 Sep 03; 285(36):27590-600. PubMed ID: 20595389 [Abstract] [Full Text] [Related]
12. Cullin 4B is recruited to tristetraprolin-containing messenger ribonucleoproteins and regulates TNF-α mRNA polysome loading. Pfeiffer JR, Brooks SA. J Immunol; 2012 Feb 15; 188(4):1828-39. PubMed ID: 22262661 [Abstract] [Full Text] [Related]
13. SIRT3, PP2A and TTP protein stability in the presence of TNF-α on vincristine-induced apoptosis of leukaemia cells. Wang LJ, Chiou JT, Lee YC, Huang CH, Shi YJ, Chang LS. J Cell Mol Med; 2020 Feb 15; 24(4):2552-2565. PubMed ID: 31930676 [Abstract] [Full Text] [Related]
14. Temporal regulation of cytokine mRNA expression by tristetraprolin: dynamic control by p38 MAPK and MKP-1. Prabhala P, Bunge K, Rahman MM, Ge Q, Clark AR, Ammit AJ. Am J Physiol Lung Cell Mol Physiol; 2015 May 01; 308(9):L973-80. PubMed ID: 25724669 [Abstract] [Full Text] [Related]
15. The role of mRNA turnover in the regulation of tristetraprolin expression: evidence for an extracellular signal-regulated kinase-specific, AU-rich element-dependent, autoregulatory pathway. Brooks SA, Connolly JE, Rigby WF. J Immunol; 2004 Jun 15; 172(12):7263-71. PubMed ID: 15187101 [Abstract] [Full Text] [Related]
16. Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin. Rahman MM, Rumzhum NN, Morris JC, Clark AR, Verrills NM, Ammit AJ. Sci Rep; 2015 May 18; 5():10063. PubMed ID: 25985190 [Abstract] [Full Text] [Related]
17. Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression. Ross EA, Naylor AJ, O'Neil JD, Crowley T, Ridley ML, Crowe J, Smallie T, Tang TJ, Turner JD, Norling LV, Dominguez S, Perlman H, Verrills NM, Kollias G, Vitek MP, Filer A, Buckley CD, Dean JL, Clark AR. Ann Rheum Dis; 2017 Mar 18; 76(3):612-619. PubMed ID: 27597652 [Abstract] [Full Text] [Related]
18. Tristetraprolin mediates radiation-induced TNF-α production in lung macrophages. Ray D, Shukla S, Allam US, Helman A, Ramanand SG, Tran L, Bassetti M, Krishnamurthy PM, Rumschlag M, Paulsen M, Sun L, Shanley TP, Ljungman M, Nyati MK, Zhang M, Lawrence TS. PLoS One; 2013 Mar 18; 8(2):e57290. PubMed ID: 23468959 [Abstract] [Full Text] [Related]
19. Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-alpha involves activation of the MKK6/p38MAPK/MK2 cascade. Ehlting C, Lai WS, Schaper F, Brenndörfer ED, Matthes RJ, Heinrich PC, Ludwig S, Blackshear PJ, Gaestel M, Häussinger D, Bode JG. J Immunol; 2007 Mar 01; 178(5):2813-26. PubMed ID: 17312125 [Abstract] [Full Text] [Related]
20. Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways. Brook M, Tchen CR, Santalucia T, McIlrath J, Arthur JS, Saklatvala J, Clark AR. Mol Cell Biol; 2006 Mar 01; 26(6):2408-18. PubMed ID: 16508015 [Abstract] [Full Text] [Related] Page: [Next] [New Search]