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PUBMED FOR HANDHELDS

Journal Abstract Search


293 related items for PubMed ID: 17178726

  • 1. Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2+ mobilization in cardiac myocytes.
    Oestreich EA, Wang H, Malik S, Kaproth-Joslin KA, Blaxall BC, Kelley GG, Dirksen RT, Smrcka AV.
    J Biol Chem; 2007 Feb 23; 282(8):5488-95. PubMed ID: 17178726
    [Abstract] [Full Text] [Related]

  • 2. Epac and phospholipase Cepsilon regulate Ca2+ release in the heart by activation of protein kinase Cepsilon and calcium-calmodulin kinase II.
    Oestreich EA, Malik S, Goonasekera SA, Blaxall BC, Kelley GG, Dirksen RT, Smrcka AV.
    J Biol Chem; 2009 Jan 16; 284(3):1514-22. PubMed ID: 18957419
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  • 3. The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes.
    Pereira L, Métrich M, Fernández-Velasco M, Lucas A, Leroy J, Perrier R, Morel E, Fischmeister R, Richard S, Bénitah JP, Lezoualc'h F, Gómez AM.
    J Physiol; 2007 Sep 01; 583(Pt 2):685-94. PubMed ID: 17599964
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  • 4. Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.
    Dzhura I, Chepurny OG, Kelley GG, Leech CA, Roe MW, Dzhura E, Afshari P, Malik S, Rindler MJ, Xu X, Lu Y, Smrcka AV, Holz GG.
    J Physiol; 2010 Dec 15; 588(Pt 24):4871-89. PubMed ID: 21041529
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  • 10. Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B.
    Evellin S, Nolte J, Tysack K, vom Dorp F, Thiel M, Weernink PA, Jakobs KH, Webb EJ, Lomasney JW, Schmidt M.
    J Biol Chem; 2002 May 10; 277(19):16805-13. PubMed ID: 11877431
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  • 12. Epac- and Ca2+ -controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors.
    Keiper M, Stope MB, Szatkowski D, Böhm A, Tysack K, Vom Dorp F, Saur O, Oude Weernink PA, Evellin S, Jakobs KH, Schmidt M.
    J Biol Chem; 2004 Nov 05; 279(45):46497-508. PubMed ID: 15319437
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  • 13. The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway.
    Yang Z, Kirton HM, MacDougall DA, Boyle JP, Deuchars J, Frater B, Ponnambalam S, Hardy ME, White E, Calaghan SC, Peers C, Steele DS.
    Sci Signal; 2015 Oct 13; 8(398):ra101. PubMed ID: 26462734
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  • 15. Epac activation induces histone deacetylase nuclear export via a Ras-dependent signalling pathway.
    Métrich M, Laurent AC, Breckler M, Duquesnes N, Hmitou I, Courillau D, Blondeau JP, Crozatier B, Lezoualc'h F, Morel E.
    Cell Signal; 2010 Oct 13; 22(10):1459-68. PubMed ID: 20576488
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  • 17. Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.
    Kang G, Joseph JW, Chepurny OG, Monaco M, Wheeler MB, Bos JL, Schwede F, Genieser HG, Holz GG.
    J Biol Chem; 2003 Mar 07; 278(10):8279-85. PubMed ID: 12496249
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  • 18. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.
    Rangarajan S, Enserink JM, Kuiperij HB, de Rooij J, Price LS, Schwede F, Bos JL.
    J Cell Biol; 2003 Feb 17; 160(4):487-93. PubMed ID: 12578910
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  • 19. EPAC1 and 2 inhibit K+ currents via PLC/PKC and NOS/PKG pathways in rat ventricular cardiomyocytes.
    Boileve A, Romito O, Hof T, Levallois A, Brard L, d'Hers S, Fouchet A, Simard C, Guinamard R, Brette F, Sallé L.
    Am J Physiol Cell Physiol; 2024 Sep 01; 327(3):C557-C570. PubMed ID: 38985989
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  • 20. Phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy.
    Wang H, Oestreich EA, Maekawa N, Bullard TA, Vikstrom KL, Dirksen RT, Kelley GG, Blaxall BC, Smrcka AV.
    Circ Res; 2005 Dec 09; 97(12):1305-13. PubMed ID: 16293787
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