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243 related items for PubMed ID: 17184496

  • 1. Attenuation of ventricular hypertrophy and fibrosis in rats by pitavastatin: potential role of the RhoA-extracellular signal-regulated kinase-serum response factor signalling pathway.
    Saka M, Obata K, Ichihara S, Cheng XW, Kimata H, Noda A, Izawa H, Nagata K, Yokota M.
    Clin Exp Pharmacol Physiol; 2006 Dec; 33(12):1164-71. PubMed ID: 17184496
    [Abstract] [Full Text] [Related]

  • 2. Pitavastatin improves cardiac function and survival in association with suppression of the myocardial endothelin system in a rat model of hypertensive heart failure.
    Saka M, Obata K, Ichihara S, Cheng XW, Kimata H, Nishizawa T, Noda A, Izawa H, Nagata K, Murohara T, Yokota M.
    J Cardiovasc Pharmacol; 2006 Jun; 47(6):770-9. PubMed ID: 16810078
    [Abstract] [Full Text] [Related]

  • 3. Simvastatin prevents large blood pressure variability induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways.
    Takayama N, Kai H, Kudo H, Yasuoka S, Mori T, Anegawa T, Koga M, Kajimoto H, Hirooka Y, Imaizumi T.
    Hypertens Res; 2011 Mar; 34(3):341-7. PubMed ID: 21124329
    [Abstract] [Full Text] [Related]

  • 4. Pitavastatin, an HMG-CoA reductase inhibitor, exerts eNOS-independent protective actions against angiotensin II induced cardiovascular remodeling and renal insufficiency.
    Yagi S, Aihara K, Ikeda Y, Sumitomo Y, Yoshida S, Ise T, Iwase T, Ishikawa K, Azuma H, Akaike M, Matsumoto T.
    Circ Res; 2008 Jan 04; 102(1):68-76. PubMed ID: 17967781
    [Abstract] [Full Text] [Related]

  • 5. Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats.
    Yamada T, Nagata K, Cheng XW, Obata K, Saka M, Miyachi M, Naruse K, Nishizawa T, Noda A, Izawa H, Kuzuya M, Okumura K, Murohara T, Yokota M.
    Eur J Pharmacol; 2009 Aug 01; 615(1-3):163-70. PubMed ID: 19501083
    [Abstract] [Full Text] [Related]

  • 6. Fluvastatin decreases cardiac fibrosis possibly through regulation of TGF-beta(1)/Smad 7 expression in the spontaneously hypertensive rats.
    Zhai Y, Gao X, Wu Q, Peng L, Lin J, Zuo Z.
    Eur J Pharmacol; 2008 Jun 10; 587(1-3):196-203. PubMed ID: 18430418
    [Abstract] [Full Text] [Related]

  • 7. [Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertension].
    Shimoyama M, Hayashi D, Zou Y, Takimoto E, Mizukami M, Monzen K, Yazaki Y, Nagai R, Komuro I.
    J Cardiol; 2001 Feb 10; 37(2):114-8. PubMed ID: 11255695
    [Abstract] [Full Text] [Related]

  • 8. RhoA expression is not a critical determinant in hypertension evolution in salt-sensitive Dahl rats.
    Yoneda T, Kihara Y, Takenaka H, Onozawa Y, Sarai N, Kita T.
    Med Sci Monit; 2003 Dec 10; 9(12):BR399-402. PubMed ID: 14646966
    [Abstract] [Full Text] [Related]

  • 9. Cardioprotective mechanism of telmisartan via PPAR-gamma-eNOS pathway in dahl salt-sensitive hypertensive rats.
    Kobayashi N, Ohno T, Yoshida K, Fukushima H, Mamada Y, Nomura M, Hirata H, Machida Y, Shinoda M, Suzuki N, Matsuoka H.
    Am J Hypertens; 2008 May 10; 21(5):576-81. PubMed ID: 18437150
    [Abstract] [Full Text] [Related]

  • 10. Effects of salt loading and various therapies on cardiac hypertrophy and fibrosis in young spontaneously hypertensive rats.
    Ziegelhöffer-Mihalovicova B, Arnold N, Marx G, Tannapfel A, Zimmer HG, Rassler B.
    Life Sci; 2006 Jul 24; 79(9):838-46. PubMed ID: 16624325
    [Abstract] [Full Text] [Related]

  • 11. Cardioprotective effects of granulocyte colony-stimulating factor in angiotensin II-induced cardiac remodelling.
    Jia N, Dong P, Huang Q, Jin W, Zhang J, Dai Q, Liu S.
    Clin Exp Pharmacol Physiol; 2009 Mar 24; 36(3):262-6. PubMed ID: 18785976
    [Abstract] [Full Text] [Related]

  • 12. Angiotensin II induced upregulation of G alpha q/11, phospholipase C beta 3 and extracellular signal-regulated kinase 1/2 via angiotensin II type 1 receptor.
    Bai H, Wu LL, Xing DQ, Liu J, Zhao YL.
    Chin Med J (Engl); 2004 Jan 24; 117(1):88-93. PubMed ID: 14733781
    [Abstract] [Full Text] [Related]

  • 13. Aldosterone-and-salt-induced cardiac fibrosis is independent from angiotensin II type 1a receptor signaling in mice.
    Kagiyama S, Matsumura K, Fukuhara M, Sakagami K, Fujii K, Iida M.
    Hypertens Res; 2007 Oct 24; 30(10):979-89. PubMed ID: 18049031
    [Abstract] [Full Text] [Related]

  • 14. MCP-1-induced enhancement of THP-1 adhesion to vascular endothelium was modulated by HMG-CoA reductase inhibitor through RhoA GTPase-, but not ERK1/2-dependent pathway.
    Hiraoka M, Nitta N, Nagai M, Shimokado K, Yoshida M.
    Life Sci; 2004 Jul 30; 75(11):1333-41. PubMed ID: 15234191
    [Abstract] [Full Text] [Related]

  • 15. HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells.
    Narumiya H, Sasaki S, Kuwahara N, Irie H, Kusaba T, Kameyama H, Tamagaki K, Hatta T, Takeda K, Matsubara H.
    Cardiovasc Res; 2004 Nov 01; 64(2):331-6. PubMed ID: 15485693
    [Abstract] [Full Text] [Related]

  • 16. Cardiac hypertrophy during hypercholesterolemia and its amelioration with rosuvastatin and amlodipine.
    Kang BY, Wang W, Palade P, Sharma SG, Mehta JL.
    J Cardiovasc Pharmacol; 2009 Oct 01; 54(4):327-34. PubMed ID: 19687748
    [Abstract] [Full Text] [Related]

  • 17. Attenuation of cardiac dysfunction by a PPAR-alpha agonist is associated with down-regulation of redox-regulated transcription factors.
    Ichihara S, Obata K, Yamada Y, Nagata K, Noda A, Ichihara G, Yamada A, Kato T, Izawa H, Murohara T, Yokota M.
    J Mol Cell Cardiol; 2006 Aug 01; 41(2):318-29. PubMed ID: 16806263
    [Abstract] [Full Text] [Related]

  • 18. Therapeutic effects of angiotensin II type 1 receptor blocker at an advanced stage of hypertensive diastolic heart failure.
    Nishio M, Sakata Y, Mano T, Yoshida J, Ohtani T, Takeda Y, Miwa T, Masuyama T, Yamamoto K, Hori M.
    J Hypertens; 2007 Feb 01; 25(2):455-61. PubMed ID: 17211254
    [Abstract] [Full Text] [Related]

  • 19. Beneficial effects of the combination of nifedipine and losartan in hypertensive Dahl salt-sensitive rats.
    Tinel H.
    J Cardiovasc Pharmacol; 2007 Jul 01; 50(1):75-82. PubMed ID: 17666919
    [Abstract] [Full Text] [Related]

  • 20. Atorvastatin ameliorates cardiac fibrosis and improves left ventricular diastolic function in hypertensive diastolic heart failure model rats.
    Akahori H, Tsujino T, Naito Y, Matsumoto M, Sasaki N, Iwasaku T, Eguchi A, Sawada H, Hirotani S, Masuyama T.
    J Hypertens; 2014 Jul 01; 32(7):1534-41; discussion 1541. PubMed ID: 24759122
    [Abstract] [Full Text] [Related]

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