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Journal Abstract Search


408 related items for PubMed ID: 1718594

  • 1. Action of 2',2'-difluorodeoxycytidine on DNA synthesis.
    Huang P, Chubb S, Hertel LW, Grindey GB, Plunkett W.
    Cancer Res; 1991 Nov 15; 51(22):6110-7. PubMed ID: 1718594
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  • 2. Excision of 2',2'-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA.
    Gandhi V, Legha J, Chen F, Hertel LW, Plunkett W.
    Cancer Res; 1996 Oct 01; 56(19):4453-9. PubMed ID: 8813140
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  • 3. Effects of gemcitabine and araC on in vitro DNA synthesis mediated by the human breast cell DNA synthesome.
    Jiang HY, Hickey RJ, Abdel-Aziz W, Malkas LH.
    Cancer Chemother Pharmacol; 2000 Oct 01; 45(4):320-8. PubMed ID: 10755321
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  • 5. [Non-clinical studies of gemcitabine--the mode of action and antitumor activities].
    Tsukagoshi S.
    Gan To Kagaku Ryoho; 1999 Feb 01; 26(3):393-400. PubMed ID: 10065109
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  • 6. Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.
    Heinemann V, Xu YZ, Chubb S, Sen A, Hertel LW, Grindey GB, Plunkett W.
    Mol Pharmacol; 1990 Oct 01; 38(4):567-72. PubMed ID: 2233693
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  • 9. Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism.
    Heinemann V, Schulz L, Issels RD, Plunkett W.
    Semin Oncol; 1995 Aug 01; 22(4 Suppl 11):11-8. PubMed ID: 7481839
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  • 12. Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine.
    Heinemann V, Hertel LW, Grindey GB, Plunkett W.
    Cancer Res; 1988 Jul 15; 48(14):4024-31. PubMed ID: 3383195
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  • 13. New Mechanism of Gemcitabine and Its Phosphates: DNA Polymerization Disruption via 3'-5' Exonuclease Inhibition.
    Yang S, Luo D, Li N, Li C, Tang S, Huang Z.
    Biochemistry; 2020 Nov 17; 59(45):4344-4352. PubMed ID: 33147009
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  • 14. Expression of ERCC1 antisense RNA abrogates gemicitabine-mediated cytotoxic synergism with cisplatin in human colon tumor cells defective in mismatch repair but proficient in nucleotide excision repair.
    Yang LY, Li L, Jiang H, Shen Y, Plunkett W.
    Clin Cancer Res; 2000 Mar 17; 6(3):773-81. PubMed ID: 10741696
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  • 15. Schedule dependence of sensitivity to 2',2'-difluorodeoxycytidine (Gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumour cell lines and solid tumours.
    Ruiz van Haperen VW, Veerman G, Boven E, Noordhuis P, Vermorken JB, Peters GJ.
    Biochem Pharmacol; 1994 Oct 07; 48(7):1327-39. PubMed ID: 7945430
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  • 16. Preclinical characteristics of gemcitabine.
    Plunkett W, Huang P, Gandhi V.
    Anticancer Drugs; 1995 Dec 07; 6 Suppl 6():7-13. PubMed ID: 8718419
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  • 17. Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase.
    Fowler JD, Brown JA, Johnson KA, Suo Z.
    J Biol Chem; 2008 May 30; 283(22):15339-48. PubMed ID: 18378680
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  • 20. Cytotoxicity, metabolism, and mechanisms of action of 2',2'-difluorodeoxyguanosine in Chinese hamster ovary cells.
    Gandhi V, Mineishi S, Huang P, Chapman AJ, Yang Y, Chen F, Nowak B, Chubb S, Hertel LW, Plunkett W.
    Cancer Res; 1995 Apr 01; 55(7):1517-24. PubMed ID: 7533664
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