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297 related items for PubMed ID: 17186945

  • 1. Microsomal prostaglandin E synthase-1 deficiency is associated with elevated peroxisome proliferator-activated receptor gamma: regulation by prostaglandin E2 via the phosphatidylinositol 3-kinase and Akt pathway.
    Kapoor M, Kojima F, Qian M, Yang L, Crofford LJ.
    J Biol Chem; 2007 Feb 23; 282(8):5356-66. PubMed ID: 17186945
    [Abstract] [Full Text] [Related]

  • 2. Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2.
    Bianchi A, Moulin D, Sebillaud S, Koufany M, Galteau MM, Netter P, Terlain B, Jouzeau JY.
    Arthritis Res Ther; 2005 Feb 23; 7(6):R1325-37. PubMed ID: 16277686
    [Abstract] [Full Text] [Related]

  • 3. Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.
    Cheng S, Afif H, Martel-Pelletier J, Pelletier JP, Li X, Farrajota K, Lavigne M, Fahmi H.
    J Biol Chem; 2004 May 21; 279(21):22057-65. PubMed ID: 15023995
    [Abstract] [Full Text] [Related]

  • 4. Coordinate functional regulation between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor γ (PPARγ) in the conversion of white-to-brown adipocytes.
    García-Alonso V, López-Vicario C, Titos E, Morán-Salvador E, González-Périz A, Rius B, Párrizas M, Werz O, Arroyo V, Clària J.
    J Biol Chem; 2013 Sep 27; 288(39):28230-42. PubMed ID: 23943621
    [Abstract] [Full Text] [Related]

  • 5. Prostaglandin E2 is an enhancer of interleukin-1beta-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts.
    Kojima F, Naraba H, Sasaki Y, Beppu M, Aoki H, Kawai S.
    Arthritis Rheum; 2003 Oct 27; 48(10):2819-28. PubMed ID: 14558087
    [Abstract] [Full Text] [Related]

  • 6. Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts.
    Yucel-Lindberg T, Olsson T, Kawakami T.
    Cell Signal; 2006 Dec 27; 18(12):2131-42. PubMed ID: 16766159
    [Abstract] [Full Text] [Related]

  • 7. Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets.
    Parazzoli S, Harmon JS, Vallerie SN, Zhang T, Zhou H, Robertson RP.
    J Biol Chem; 2012 Sep 14; 287(38):32246-53. PubMed ID: 22822059
    [Abstract] [Full Text] [Related]

  • 8. Glucosamine sulfate reduces prostaglandin E(2) production in osteoarthritic chondrocytes through inhibition of microsomal PGE synthase-1.
    Kapoor M, Mineau F, Fahmi H, Pelletier JP, Martel-Pelletier J.
    J Rheumatol; 2012 Mar 14; 39(3):635-44. PubMed ID: 22089456
    [Abstract] [Full Text] [Related]

  • 9. Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1.
    Jüngel A, Distler O, Schulze-Horsel U, Huber LC, Ha HR, Simmen B, Kalden JR, Pisetsky DS, Gay S, Distler JH.
    Arthritis Rheum; 2007 Nov 14; 56(11):3564-74. PubMed ID: 17968936
    [Abstract] [Full Text] [Related]

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  • 11. Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.
    Li X, Afif H, Cheng S, Martel-Pelletier J, Pelletier JP, Ranger P, Fahmi H.
    J Rheumatol; 2005 May 14; 32(5):887-95. PubMed ID: 15868626
    [Abstract] [Full Text] [Related]

  • 12. Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase-1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis.
    Kapoor M, Kojima F, Qian M, Yang L, Crofford LJ.
    FASEB J; 2006 Nov 14; 20(13):2387-9. PubMed ID: 17023389
    [Abstract] [Full Text] [Related]

  • 13. Up-regulation of prostaglandin E2 synthesis by interleukin-1beta in human orbital fibroblasts involves coordinate induction of prostaglandin-endoperoxide H synthase-2 and glutathione-dependent prostaglandin E2 synthase expression.
    Han R, Tsui S, Smith TJ.
    J Biol Chem; 2002 May 10; 277(19):16355-64. PubMed ID: 11847219
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1.
    Gosset M, Pigenet A, Salvat C, Berenbaum F, Jacques C.
    J Immunol; 2010 Nov 15; 185(10):6244-52. PubMed ID: 20943996
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  • 16. Involvement of PGE2 and the cAMP signalling pathway in the up-regulation of COX-2 and mPGES-1 expression in LPS-activated macrophages.
    Díaz-Muñoz MD, Osma-García IC, Fresno M, Iñiguez MA.
    Biochem J; 2012 Apr 15; 443(2):451-61. PubMed ID: 22268508
    [Abstract] [Full Text] [Related]

  • 17. LDL-Dependent Regulation of TNFα/PGE2 Induced COX-2/mPGES-1 Expression in Human Macrophage Cell Lines.
    Neuschäfer-Rube F, Schön T, Kahnt I, Püschel GP.
    Inflammation; 2023 Jun 15; 46(3):893-911. PubMed ID: 36598592
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  • 19. Angiotensin II differentially modulates cyclooxygenase-2, microsomal prostaglandin E2 synthase-1 and prostaglandin I2 synthase expression in adventitial fibroblasts exposed to inflammatory stimuli.
    Galán M, Miguel M, Beltrán AE, Rodríguez C, García-Redondo AB, Rodríguez-Calvo R, Alonso MJ, Martínez-González J, Salaices M.
    J Hypertens; 2011 Mar 15; 29(3):529-36. PubMed ID: 21169864
    [Abstract] [Full Text] [Related]

  • 20. Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.
    Brenneis C, Coste O, Altenrath K, Angioni C, Schmidt H, Schuh CD, Zhang DD, Henke M, Weigert A, Brüne B, Rubin B, Nusing R, Scholich K, Geisslinger G.
    J Biol Chem; 2011 Jan 21; 286(3):2331-42. PubMed ID: 21075851
    [Abstract] [Full Text] [Related]

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