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86 related items for PubMed ID: 17192652

  • 1. Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors.
    Jakubík J, Dolezal V.
    J Mol Neurosci; 2006; 30(1-2):111-2. PubMed ID: 17192652
    [Abstract] [Full Text] [Related]

  • 2. Asparagine, valine, and threonine in the third extracellular loop of muscarinic receptor have essential roles in the positive cooperativity of strychnine-like allosteric modulators.
    Jakubík J, Krejcí A, Dolezal V.
    J Pharmacol Exp Ther; 2005 May; 313(2):688-96. PubMed ID: 15647330
    [Abstract] [Full Text] [Related]

  • 3. Changes of cooperativity between N-methylscopolamine and allosteric modulators alcuronium and gallamine induced by mutations of external loops of muscarinic M(3) receptors.
    Krejcí A, Tucek S.
    Mol Pharmacol; 2001 Oct; 60(4):761-7. PubMed ID: 11562438
    [Abstract] [Full Text] [Related]

  • 4. Allosteric interactions of quaternary strychnine and brucine derivatives with muscarinic acetylcholine receptors.
    Gharagozloo P, Lazareno S, Popham A, Birdsall NJ.
    J Med Chem; 1999 Feb 11; 42(3):438-45. PubMed ID: 9986715
    [Abstract] [Full Text] [Related]

  • 5. Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors.
    Voigtländer U, Jöhren K, Mohr M, Raasch A, Tränkle C, Buller S, Ellis J, Höltje HD, Mohr K.
    Mol Pharmacol; 2003 Jul 11; 64(1):21-31. PubMed ID: 12815157
    [Abstract] [Full Text] [Related]

  • 6. Subtype-selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: radioligand binding studies.
    Lazareno S, Gharagozloo P, Kuonen D, Popham A, Birdsall NJ.
    Mol Pharmacol; 1998 Mar 11; 53(3):573-89. PubMed ID: 9495826
    [Abstract] [Full Text] [Related]

  • 7. Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors.
    Zlotos DP, Buller S, Holzgrabe U, Mohr K.
    Bioorg Med Chem; 2003 Jun 12; 11(12):2627-34. PubMed ID: 12757728
    [Abstract] [Full Text] [Related]

  • 8. Positive allosteric action of eburnamonine on cardiac muscarinic acetylcholine receptors.
    Proska J, Tucek S.
    Eur J Pharmacol; 1996 Jun 03; 305(1-3):201-5. PubMed ID: 8813554
    [Abstract] [Full Text] [Related]

  • 9. Mutational disruption of a conserved disulfide bond in muscarinic acetylcholine receptors attenuates positive homotropic cooperativity between multiple allosteric sites and has subtype-dependent effects on the affinities of muscarinic allosteric ligands.
    Huang XP, Ellis J.
    Mol Pharmacol; 2007 Mar 03; 71(3):759-68. PubMed ID: 17132687
    [Abstract] [Full Text] [Related]

  • 10. Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors.
    Jakubík J, Bacáková L, el-Fakahany EE, Tucek S.
    J Pharmacol Exp Ther; 1995 Sep 03; 274(3):1077-83. PubMed ID: 7562472
    [Abstract] [Full Text] [Related]

  • 11. Competition between positive and negative allosteric effectors on muscarinic receptors.
    Proska J, Tucek S.
    Mol Pharmacol; 1995 Oct 03; 48(4):696-702. PubMed ID: 7476896
    [Abstract] [Full Text] [Related]

  • 12. Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists.
    Lysíková M, Havlas Z, Tucek S.
    Neurochem Res; 2001 Apr 03; 26(4):383-94. PubMed ID: 11495349
    [Abstract] [Full Text] [Related]

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  • 16. Three allosteric modulators act at a common site, distinct from that of competitive antagonists, at muscarinic acetylcholine M2 receptors.
    Lanzafame A, Christopoulos A, Mitchelson F.
    J Pharmacol Exp Ther; 1997 Jul 03; 282(1):278-85. PubMed ID: 9223565
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  • 17. Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor.
    Leppik RA, Miller RC, Eck M, Paquet JL.
    Mol Pharmacol; 1994 May 03; 45(5):983-90. PubMed ID: 8190113
    [Abstract] [Full Text] [Related]

  • 18. Interactions of alcuronium, TMB-8, and other allosteric ligands with muscarinic acetylcholine receptors: studies with chimeric receptors.
    Ellis J, Seidenberg M.
    Mol Pharmacol; 2000 Dec 03; 58(6):1451-60. PubMed ID: 11093785
    [Abstract] [Full Text] [Related]

  • 19. Allosteric site on muscarinic acetylcholine receptors: a single amino acid in transmembrane region 7 is critical to the subtype selectivities of caracurine V derivatives and alkane-bisammonium ligands.
    Buller S, Zlotos DP, Mohr K, Ellis J.
    Mol Pharmacol; 2002 Jan 03; 61(1):160-8. PubMed ID: 11752217
    [Abstract] [Full Text] [Related]

  • 20. Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors.
    Tränkle C, Weyand O, Voigtländer U, Mynett A, Lazareno S, Birdsall NJ, Mohr K.
    Mol Pharmacol; 2003 Jul 03; 64(1):180-90. PubMed ID: 12815174
    [Abstract] [Full Text] [Related]

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