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359 related items for PubMed ID: 17210716

  • 1. Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation.
    Vogel C, Hager C, Bastians H.
    Cancer Res; 2007 Jan 01; 67(1):339-45. PubMed ID: 17210716
    [Abstract] [Full Text] [Related]

  • 2. Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic catastrophe.
    Tse AN, Schwartz GK.
    Cancer Res; 2004 Sep 15; 64(18):6635-44. PubMed ID: 15374978
    [Abstract] [Full Text] [Related]

  • 3. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
    Castedo M, Perfettini JL, Roumier T, Yakushijin K, Horne D, Medema R, Kroemer G.
    Oncogene; 2004 May 27; 23(25):4353-61. PubMed ID: 15048074
    [Abstract] [Full Text] [Related]

  • 4. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.
    Chung KS, Choi HE, Shin JS, Cho YW, Choi JH, Cho WJ, Lee KT.
    Carcinogenesis; 2013 Aug 27; 34(8):1852-60. PubMed ID: 23615402
    [Abstract] [Full Text] [Related]

  • 5. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Hirose Y, Berger MS, Pieper RO.
    Cancer Res; 2001 Aug 01; 61(15):5843-9. PubMed ID: 11479224
    [Abstract] [Full Text] [Related]

  • 6. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.
    Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS.
    J Cell Biol; 2003 Apr 28; 161(2):267-80. PubMed ID: 12719470
    [Abstract] [Full Text] [Related]

  • 7. Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension.
    Lens SM, Wolthuis RM, Klompmaker R, Kauw J, Agami R, Brummelkamp T, Kops G, Medema RH.
    EMBO J; 2003 Jun 16; 22(12):2934-47. PubMed ID: 12805209
    [Abstract] [Full Text] [Related]

  • 8. Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
    Stolz A, Vogel C, Schneider V, Ertych N, Kienitz A, Yu H, Bastians H.
    Cancer Res; 2009 May 01; 69(9):3874-83. PubMed ID: 19366805
    [Abstract] [Full Text] [Related]

  • 9. An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner.
    Noh EJ, Lim DS, Jeong G, Lee JS.
    Biochem Biophys Res Commun; 2009 Jan 16; 378(3):326-31. PubMed ID: 19038231
    [Abstract] [Full Text] [Related]

  • 10. Determinants of mitotic catastrophe on abrogation of the G2 DNA damage checkpoint by UCN-01.
    On KF, Chen Y, Ma HT, Chow JP, Poon RY.
    Mol Cancer Ther; 2011 May 16; 10(5):784-94. PubMed ID: 21430130
    [Abstract] [Full Text] [Related]

  • 11. Mitotic arrest deficient 2 expression induces chemosensitization to a DNA-damaging agent, cisplatin, in nasopharyngeal carcinoma cells.
    Cheung HW, Jin DY, Ling MT, Wong YC, Wang Q, Tsao SW, Wang X.
    Cancer Res; 2005 Feb 15; 65(4):1450-8. PubMed ID: 15735033
    [Abstract] [Full Text] [Related]

  • 12. Cell cycle-dependent potentiation of cisplatin by UCN-01 in non-small-cell lung carcinoma.
    Mack PC, Gandara DR, Lau AH, Lara PN, Edelman MJ, Gumerlock PH.
    Cancer Chemother Pharmacol; 2003 Apr 15; 51(4):337-48. PubMed ID: 12721762
    [Abstract] [Full Text] [Related]

  • 13. UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.
    Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM.
    J Natl Cancer Inst; 1996 Jul 17; 88(14):956-65. PubMed ID: 8667426
    [Abstract] [Full Text] [Related]

  • 14. BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines.
    Greene LM, Campiani G, Lawler M, Williams DC, Zisterer DM.
    Mol Pharmacol; 2008 Feb 17; 73(2):419-30. PubMed ID: 17991869
    [Abstract] [Full Text] [Related]

  • 15. Requirement of a functional spindle checkpoint for arsenite-induced apoptosis.
    Wu YC, Yen WY, Yih LH.
    J Cell Biochem; 2008 Oct 15; 105(3):678-87. PubMed ID: 18668508
    [Abstract] [Full Text] [Related]

  • 16. Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation.
    Liu X, Guo Y, Li Y, Jiang Y, Chubb S, Azuma A, Huang P, Matsuda A, Hittelman W, Plunkett W.
    Cancer Res; 2005 Aug 01; 65(15):6874-81. PubMed ID: 16061671
    [Abstract] [Full Text] [Related]

  • 17. Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines.
    Tsuiki H, Nitta M, Tada M, Inagaki M, Ushio Y, Saya H.
    Oncogene; 2001 Jan 25; 20(4):420-9. PubMed ID: 11313973
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of AKT enhances mitotic cell apoptosis induced by arsenic trioxide.
    Yih LH, Hsu NC, Wu YC, Yen WY, Kuo HH.
    Toxicol Appl Pharmacol; 2013 Mar 15; 267(3):228-37. PubMed ID: 23352504
    [Abstract] [Full Text] [Related]

  • 19. Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity.
    Beardmore VA, Ahonen LJ, Gorbsky GJ, Kallio MJ.
    J Cell Sci; 2004 Aug 15; 117(Pt 18):4033-42. PubMed ID: 15280424
    [Abstract] [Full Text] [Related]

  • 20. MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells.
    Wang X, Jin DY, Wong HL, Feng H, Wong YC, Tsao SW.
    Oncogene; 2003 Jan 09; 22(1):109-16. PubMed ID: 12527913
    [Abstract] [Full Text] [Related]

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