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402 related items for PubMed ID: 17213520

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  • 3. The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population.
    Cáliz R, del Amo J, Balsa A, Blanco F, Silva L, Sanmarti R, Martínez FG, Collado MD, Ramirez Mdel C, Tejedor D, Artieda M, Pascual-Salcedo D, Oreiro N, Andreu JL, Graell E, Simon L, Martínez A, Mulero J.
    Scand J Rheumatol; 2012 Feb; 41(1):10-4. PubMed ID: 22044028
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  • 4. Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
    Wessels JA, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YP, Allaart CF, Kerstens PJ, van Zeben D, Breedveld FC, Dijkmans BA, Huizinga TW, Guchelaar HJ.
    Arthritis Rheum; 2006 Apr; 54(4):1087-95. PubMed ID: 16572443
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  • 5. Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene.
    Berkun Y, Levartovsky D, Rubinow A, Orbach H, Aamar S, Grenader T, Abou Atta I, Mevorach D, Friedman G, Ben-Yehuda A.
    Ann Rheum Dis; 2004 Oct; 63(10):1227-31. PubMed ID: 15361376
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  • 6. Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
    Schmeling H, Biber D, Heins S, Horneff G.
    J Rheumatol; 2005 Sep; 32(9):1832-6. PubMed ID: 16142884
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  • 7. 677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis.
    Kurzawski M, Pawlik A, Safranow K, Herczynska M, Drozdzik M.
    Pharmacogenomics; 2007 Nov; 8(11):1551-9. PubMed ID: 18034620
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  • 8. Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate.
    Kim SK, Jun JB, El-Sohemy A, Bae SC.
    J Rheumatol; 2006 Jul; 33(7):1266-74. PubMed ID: 16758511
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  • 9. Methylene tetrahydrofolate reductase genotypes frequencies: association with toxicity and response to methotrexate in rheumatoid arthritis patients.
    Saleh MM, Irshaid YM, Mustafa KN.
    Int J Clin Pharmacol Ther; 2015 Feb; 53(2):154-62. PubMed ID: 25492850
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  • 10. Methylenetetrahydrofolate reductase polymorphisms and methotrexate: no association with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients.
    Taraborelli M, Andreoli L, Archetti S, Ferrari M, Cattaneo R, Tincani A.
    Clin Exp Rheumatol; 2009 Feb; 27(3):499-502. PubMed ID: 19604445
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  • 11. Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis.
    van Ede AE, Laan RF, Blom HJ, Boers GH, Haagsma CJ, Thomas CM, De Boo TM, van de Putte LB.
    Rheumatology (Oxford); 2002 Jun; 41(6):658-65. PubMed ID: 12048292
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  • 12. Common polymorphisms in the folate pathway predict efficacy of combination regimens containing methotrexate and sulfasalazine in early rheumatoid arthritis.
    James HM, Gillis D, Hissaria P, Lester S, Somogyi AA, Cleland LG, Proudman SM.
    J Rheumatol; 2008 Apr; 35(4):562-71. PubMed ID: 18322994
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  • 13. Association of low baseline levels of erythrocyte folate with treatment nonresponse at three months in rheumatoid arthritis patients receiving methotrexate.
    de Rotte MC, de Jong PH, Pluijm SM, Calasan MB, Barendregt PJ, van Zeben D, van der Lubbe PA, de Sonnaville PB, Lindemans J, Hazes JM, de Jonge R.
    Arthritis Rheum; 2013 Nov; 65(11):2803-13. PubMed ID: 24166792
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  • 14. Association Between MTHFR C677T Polymorphism and Methotrexate Treatment Outcome in Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis.
    Shao W, Yuan Y, Li Y.
    Genet Test Mol Biomarkers; 2017 May; 21(5):275-285. PubMed ID: 28277784
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  • 15. The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients.
    van Ede AE, Laan RF, Blom HJ, Huizinga TW, Haagsma CJ, Giesendorf BA, de Boo TM, van de Putte LB.
    Arthritis Rheum; 2001 Nov; 44(11):2525-30. PubMed ID: 11710708
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  • 16. Genetic Determinants of Methotrexate Toxicity in Tunisian Patients with Rheumatoid Arthritis: A Study of Polymorphisms Involved in the MTX Metabolic Pathway.
    Chaabane S, Marzouk S, Akrout R, Ben Hamad M, Achour Y, Rebai A, Keskes L, Fourati H, Bahloul Z, Maalej A.
    Eur J Drug Metab Pharmacokinet; 2016 Aug; 41(4):385-93. PubMed ID: 26077125
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  • 17. Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate.
    Stamp LK, Chapman PT, O'Donnell JL, Zhang M, James J, Frampton C, Barclay ML, Kennedy MA, Roberts RL.
    Pharmacogenet Genomics; 2010 Jun; 20(6):367-76. PubMed ID: 20386493
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  • 18. Reduction of the efficacy of methotrexate by the use of folic acid: post hoc analysis from two randomized controlled studies.
    Khanna D, Park GS, Paulus HE, Simpson KM, Elashoff D, Cohen SB, Emery P, Dorrier C, Furst DE.
    Arthritis Rheum; 2005 Oct; 52(10):3030-8. PubMed ID: 16200612
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  • 19. The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients.
    Soukup T, Dosedel M, Pavek P, Nekvindova J, Barvik I, Bubancova I, Bradna P, Kubena AA, Carazo AF, Veleta T, Vlcek J.
    Rheumatol Int; 2015 Jul; 35(7):1149-61. PubMed ID: 25618758
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  • 20. Pharmacogenetic polymorphisms contributing to toxicity induced by methotrexate in the southern Spanish population with rheumatoid arthritis.
    Plaza-Plaza JC, Aguilera M, Cañadas-Garre M, Chemello C, González-Utrilla A, Faus Dader MJ, Calleja MA.
    OMICS; 2012 Nov; 16(11):589-95. PubMed ID: 23095111
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