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Journal Abstract Search

240 related items for PubMed ID: 17214439

  • 1. Structure-aided design of inhibitors of Mycobacterium tuberculosis thymidylate kinase.
    Van Calenbergh S.
    Verh K Acad Geneeskd Belg; 2006; 68(4):223-48. PubMed ID: 17214439
    [Abstract] [Full Text] [Related]

  • 2. Drug design and identification of potent leads against mycobacterium tuberculosis thymidine monophosphate kinase.
    Van Calenbergh S, Pochet S, Munier-Lehmann H.
    Curr Top Med Chem; 2012; 12(7):694-705. PubMed ID: 22283813
    [Abstract] [Full Text] [Related]

  • 3. Exploring acyclic nucleoside analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
    Familiar O, Munier-Lehmann H, Negri A, Gago F, Douguet D, Rigouts L, Hernández AI, Camarasa MJ, Pérez-Pérez MJ.
    ChemMedChem; 2008 Jul; 3(7):1083-93. PubMed ID: 18418833
    [Abstract] [Full Text] [Related]

  • 4. Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
    Vanheusden V, Munier-Lehmann H, Froeyen M, Busson R, Rozenski J, Herdewijn P, Van Calenbergh S.
    J Med Chem; 2004 Dec 02; 47(25):6187-94. PubMed ID: 15566289
    [Abstract] [Full Text] [Related]

  • 5. A new family of inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
    Gasse C, Huteau V, Douguet D, Munier-Lehmann H, Pochet S.
    Nucleosides Nucleotides Nucleic Acids; 2007 Dec 02; 26(8-9):1057-61. PubMed ID: 18058536
    [No Abstract] [Full Text] [Related]

  • 6. Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.
    Pochet S, Dugué L, Labesse G, Delepierre M, Munier-Lehmann H.
    Chembiochem; 2003 Aug 04; 4(8):742-7. PubMed ID: 12898625
    [Abstract] [Full Text] [Related]

  • 7. Knowledge based identification of potent antitubercular compounds using structure based virtual screening and structure interaction fingerprints.
    Kumar A, Chaturvedi V, Bhatnagar S, Sinha S, Siddiqi MI.
    J Chem Inf Model; 2009 Jan 04; 49(1):35-42. PubMed ID: 19063713
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors.
    Toti KS, Verbeke F, Risseeuw MD, Frecer V, Munier-Lehmann H, Van Calenbergh S.
    Bioorg Med Chem; 2013 Jan 01; 21(1):257-68. PubMed ID: 23199481
    [Abstract] [Full Text] [Related]

  • 9. 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
    Vanheusden V, Munier-Lehmann H, Froeyen M, Dugué L, Heyerick A, De Keukeleire D, Pochet S, Busson R, Herdewijn P, Van Calenbergh S.
    J Med Chem; 2003 Aug 28; 46(18):3811-21. PubMed ID: 12930144
    [Abstract] [Full Text] [Related]

  • 10. Rational design and 3D-pharmacophore mapping of 5'-thiourea-substituted alpha-thymidine analogues as mycobacterial TMPK inhibitors.
    Andrade CH, Pasqualoto KF, Ferreira EI, Hopfinger AJ.
    J Chem Inf Model; 2009 Apr 28; 49(4):1070-8. PubMed ID: 19296716
    [Abstract] [Full Text] [Related]

  • 11. Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial activity.
    Gasse C, Douguet D, Huteau V, Marchal G, Munier-Lehmann H, Pochet S.
    Bioorg Med Chem; 2008 Jun 01; 16(11):6075-85. PubMed ID: 18467107
    [Abstract] [Full Text] [Related]

  • 12. Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
    Van Daele I, Munier-Lehmann H, Froeyen M, Balzarini J, Van Calenbergh S.
    J Med Chem; 2007 Nov 01; 50(22):5281-92. PubMed ID: 17910427
    [Abstract] [Full Text] [Related]

  • 13. Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.
    Munier-Lehmann H, Pochet S, Dugue L, Dutruel O, Labesse G, Douget D.
    Nucleosides Nucleotides Nucleic Acids; 2003 Nov 01; 22(5-8):801-4. PubMed ID: 14565282
    [No Abstract] [Full Text] [Related]

  • 14. Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase.
    Van Poecke S, Munier-Lehmann H, Helynck O, Froeyen M, Van Calenbergh S.
    Bioorg Med Chem; 2011 Dec 15; 19(24):7603-11. PubMed ID: 22061826
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and inhibitory activity against Mycobacterium tuberculosis thymidine monophosphate kinase of acyclic nucleoside analogues with a distal imidazoquinolinone.
    Familiar O, Munier-Lehmann H, Aínsa JA, Camarasa MJ, Pérez-Pérez MJ.
    Eur J Med Chem; 2010 Dec 15; 45(12):5910-8. PubMed ID: 20951473
    [Abstract] [Full Text] [Related]

  • 16. A virtual screening approach for thymidine monophosphate kinase inhibitors as antitubercular agents based on docking and pharmacophore models.
    Gopalakrishnan B, Aparna V, Jeevan J, Ravi M, Desiraju GR.
    J Chem Inf Model; 2005 Dec 15; 45(4):1101-8. PubMed ID: 16045305
    [Abstract] [Full Text] [Related]

  • 17. Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
    Vanheusden V, Van Rompaey P, Munier-Lehmann H, Pochet S, Herdewijn P, Van Calenbergh S.
    Bioorg Med Chem Lett; 2003 Sep 15; 13(18):3045-8. PubMed ID: 12941330
    [Abstract] [Full Text] [Related]

  • 18. Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents.
    Song L, Risseeuw MDP, Froeyen M, Karalic I, Goeman J, Cappoen D, Van der Eycken J, Cos P, Munier-Lehmann H, Van Calenbergh S.
    Bioorg Med Chem; 2016 Nov 01; 24(21):5172-5182. PubMed ID: 27614917
    [Abstract] [Full Text] [Related]

  • 19. 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.
    Aparna V, Jeevan J, Ravi M, Desiraju GR, Gopalakrishnan B.
    Bioorg Med Chem Lett; 2006 Feb 15; 16(4):1014-20. PubMed ID: 16290929
    [Abstract] [Full Text] [Related]

  • 20. 5-Arylaminouracil Derivatives: New Inhibitors of Mycobacterium tuberculosis.
    Matyugina E, Novikov M, Babkov D, Ozerov A, Chernousova L, Andreevskaya S, Smirnova T, Karpenko I, Chizhov A, Murthu P, Lutz S, Kochetkov S, Seley-Radtke KL, Khandazhinskaya AL.
    Chem Biol Drug Des; 2015 Dec 15; 86(6):1387-96. PubMed ID: 26061192
    [Abstract] [Full Text] [Related]

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