These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

389 related items for PubMed ID: 17223266

  • 1. Inhibition of Abeta production by NF-kappaB inhibitors.
    Paris D, Patel N, Quadros A, Linan M, Bakshi P, Ait-Ghezala G, Mullan M.
    Neurosci Lett; 2007 Mar 19; 415(1):11-6. PubMed ID: 17223266
    [Abstract] [Full Text] [Related]

  • 2. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I, Hawkins J, Harrison D, Hille C, Wayne G, Cutler L, Buck T, Walter D, Demont E, Howes C, Naylor A, Jeffrey P, Gonzalez MI, Dingwall C, Michel A, Redshaw S, Davis JB.
    J Neurochem; 2007 Feb 19; 100(3):802-9. PubMed ID: 17156133
    [Abstract] [Full Text] [Related]

  • 3. P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.
    Meredith JE, Thompson LA, Toyn JH, Marcin L, Barten DM, Marcinkeviciene J, Kopcho L, Kim Y, Lin A, Guss V, Burton C, Iben L, Polson C, Cantone J, Ford M, Drexler D, Fiedler T, Lentz KA, Grace JE, Kolb J, Corsa J, Pierdomenico M, Jones K, Olson RE, Macor JE, Albright CF.
    J Pharmacol Exp Ther; 2008 Aug 19; 326(2):502-13. PubMed ID: 18499745
    [Abstract] [Full Text] [Related]

  • 4. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J, Ayral E, Hernandez JF, Martinez J, Checler F.
    J Neurochem; 2009 Jul 19; 110(1):275-83. PubMed ID: 19457123
    [Abstract] [Full Text] [Related]

  • 5. Etazolate, a neuroprotective drug linking GABA(A) receptor pharmacology to amyloid precursor protein processing.
    Marcade M, Bourdin J, Loiseau N, Peillon H, Rayer A, Drouin D, Schweighoffer F, Désiré L.
    J Neurochem; 2008 Jul 19; 106(1):392-404. PubMed ID: 18397369
    [Abstract] [Full Text] [Related]

  • 6. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
    Martone RL, Zhou H, Atchison K, Comery T, Xu JZ, Huang X, Gong X, Jin M, Kreft A, Harrison B, Mayer SC, Aschmies S, Gonzales C, Zaleska MM, Riddell DR, Wagner E, Lu P, Sun SC, Sonnenberg-Reines J, Oganesian A, Adkins K, Leach MW, Clarke DW, Huryn D, Abou-Gharbia M, Magolda R, Bard J, Frick G, Raje S, Forlow SB, Balliet C, Burczynski ME, Reinhart PH, Wan HI, Pangalos MN, Jacobsen JS.
    J Pharmacol Exp Ther; 2009 Nov 19; 331(2):598-608. PubMed ID: 19671883
    [Abstract] [Full Text] [Related]

  • 7. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J, Williamson NA, Hill AF, Sernee MF, Masters CL, Small DH.
    J Neurosci Res; 2003 Nov 01; 74(3):378-85. PubMed ID: 14598314
    [Abstract] [Full Text] [Related]

  • 8. BACE inhibitor reduces APP-beta-C-terminal fragment accumulation in axonal swellings of okadaic acid-induced neurodegeneration.
    Yoon SY, Choi JE, Yoon JH, Huh JW, Kim DH.
    Neurobiol Dis; 2006 May 01; 22(2):435-44. PubMed ID: 16480887
    [Abstract] [Full Text] [Related]

  • 9. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S, Price EA, Wu G, Crouthamel MC, Shi XP, Tugusheva K, Tyler KX, Kahana J, Ellis J, Jin L, Steele T, Stachel S, Coburn C, Simon AJ.
    J Pharmacol Exp Ther; 2008 Mar 01; 324(3):957-69. PubMed ID: 18156464
    [Abstract] [Full Text] [Related]

  • 10. Lactacystin decreases amyloid-beta peptide production by inhibiting beta-secretase activity.
    Kienlen-Campard P, Feyt C, Huysseune S, de Diesbach P, N'Kuli F, Courtoy PJ, Octave JN.
    J Neurosci Res; 2006 Nov 01; 84(6):1311-22. PubMed ID: 16941495
    [Abstract] [Full Text] [Related]

  • 11. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
    Vingtdeux V, Hamdane M, Gompel M, Bégard S, Drobecq H, Ghestem A, Grosjean ME, Kostanjevecki V, Grognet P, Vanmechelen E, Buée L, Delacourte A, Sergeant N.
    Neurobiol Dis; 2005 Nov 01; 20(2):625-37. PubMed ID: 15936948
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of amyloid beta-peptide production by blockage of beta-secretase cleavage site of amyloid precursor protein.
    Na CH, Jeon SH, Zhang G, Olson GL, Chae CB.
    J Neurochem; 2007 Jun 01; 101(6):1583-95. PubMed ID: 17542811
    [Abstract] [Full Text] [Related]

  • 13. Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides.
    Bourne KZ, Ferrari DC, Lange-Dohna C, Rossner S, Wood TG, Perez-Polo JR.
    J Neurosci Res; 2007 May 01; 85(6):1194-204. PubMed ID: 17385716
    [Abstract] [Full Text] [Related]

  • 14. Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.
    Funamoto S, Morishima-Kawashima M, Tanimura Y, Hirotani N, Saido TC, Ihara Y.
    Biochemistry; 2004 Oct 26; 43(42):13532-40. PubMed ID: 15491160
    [Abstract] [Full Text] [Related]

  • 15. Immunotherapy against APP beta-secretase cleavage site improves cognitive function and reduces neuroinflammation in Tg2576 mice without a significant effect on brain abeta levels.
    Rakover I, Arbel M, Solomon B.
    Neurodegener Dis; 2007 Oct 26; 4(5):392-402. PubMed ID: 17536186
    [Abstract] [Full Text] [Related]

  • 16. Effects of huperzine A on amyloid precursor protein processing and beta-amyloid generation in human embryonic kidney 293 APP Swedish mutant cells.
    Peng Y, Jiang L, Lee DY, Schachter SC, Ma Z, Lemere CA.
    J Neurosci Res; 2006 Sep 26; 84(4):903-11. PubMed ID: 16862548
    [Abstract] [Full Text] [Related]

  • 17. [Therapy of Alzheimer disease].
    Kovács T.
    Neuropsychopharmacol Hung; 2009 Mar 26; 11(1):27-33. PubMed ID: 19731816
    [Abstract] [Full Text] [Related]

  • 18. Characterization of Abeta11-40/42 peptide deposition in Alzheimer's disease and young Down's syndrome brains: implication of N-terminally truncated Abeta species in the pathogenesis of Alzheimer's disease.
    Liu K, Solano I, Mann D, Lemere C, Mercken M, Trojanowski JQ, Lee VM.
    Acta Neuropathol; 2006 Aug 26; 112(2):163-74. PubMed ID: 16865398
    [Abstract] [Full Text] [Related]

  • 19. The novel beta-secretase inhibitor KMI-429 reduces amyloid beta peptide production in amyloid precursor protein transgenic and wild-type mice.
    Asai M, Hattori C, Iwata N, Saido TC, Sasagawa N, Szabó B, Hashimoto Y, Maruyama K, Tanuma S, Kiso Y, Ishiura S.
    J Neurochem; 2006 Jan 26; 96(2):533-40. PubMed ID: 16336629
    [Abstract] [Full Text] [Related]

  • 20. Nicotinic receptor agonists and antagonists increase sAPPalpha secretion and decrease Abeta levels in vitro.
    Mousavi M, Hellström-Lindahl E.
    Neurochem Int; 2009 Jan 26; 54(3-4):237-44. PubMed ID: 19111588
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 20.