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157 related items for PubMed ID: 1722550

  • 1. Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia.
    Lin JT, Tong WP, Trippett TM, Niedzwiecki D, Tao Y, Tan C, Steinherz P, Schweitzer BI, Bertino JR.
    Leuk Res; 1991; 15(12):1191-6. PubMed ID: 1722550
    [Abstract] [Full Text] [Related]

  • 2. Acute monocytic leukemia: a myeloid leukemia subset that may be sensitive to methotrexate.
    Göker E, Kheradpour A, Waltham M, Banerjee D, Tong WP, Elisseyeff Y, Bertino JR.
    Leukemia; 1995 Feb; 9(2):274-6. PubMed ID: 7532768
    [Abstract] [Full Text] [Related]

  • 3. Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease.
    Göker E, Lin JT, Trippett T, Elisseyeff Y, Tong WP, Niedzwiecki D, Tan C, Steinherz P, Schweitzer BI, Bertino JR.
    Leukemia; 1993 Jul; 7(7):1000-4. PubMed ID: 7686600
    [Abstract] [Full Text] [Related]

  • 4. Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation.
    Jaramillo AC, Cloos J, Lemos C, Stam RW, Kaspers GJL, Jansen G, Peters GJ.
    Leuk Res; 2019 Apr; 79():45-51. PubMed ID: 30849662
    [Abstract] [Full Text] [Related]

  • 5. Time course of methotrexate polyglutamate formation and degradation in the pre-B-leukaemia cell line Nalm6 and in lymphoblasts from children with leukaemia.
    Buchholz B, Frei E, Eisenbarth J, Weigand M, Ludwig R.
    Eur J Cancer; 1996 Nov; 32A(12):2101-7. PubMed ID: 9014752
    [Abstract] [Full Text] [Related]

  • 6. Comparative analysis of methotrexate polyglutamates in lymphoblast preparations from bone marrow and blood, and the contribution of residual red blood cells.
    Weigand M, Frei E, Graf N, Wiessler M.
    J Cancer Res Clin Oncol; 2000 Jul; 126(7):407-11. PubMed ID: 10929763
    [Abstract] [Full Text] [Related]

  • 7. Evidence for negative feedback of extracellular methotrexate on blasts of acute lymphoblastic leukemia in vitro.
    Hum MC, Smith AK, Lark RH, Winick NJ, Kamen BA.
    Pharmacotherapy; 1997 Jul; 17(6):1260-6. PubMed ID: 9399609
    [Abstract] [Full Text] [Related]

  • 8. Intrinsic resistance of cervical squamous cell carcinoma cell lines to methotrexate (MTX) as a result of decreased accumulation of intracellular MTX polyglutamates.
    Barakat RR, Li WW, Lovelace C, Bertino JR.
    Gynecol Oncol; 1993 Oct; 51(1):54-60. PubMed ID: 7694891
    [Abstract] [Full Text] [Related]

  • 9. Defective transport as a mechanism of acquired resistance to methotrexate in patients with acute lymphocytic leukemia.
    Trippett T, Schlemmer S, Elisseyeff Y, Goker E, Wachter M, Steinherz P, Tan C, Berman E, Wright JE, Rosowsky A.
    Blood; 1992 Sep 01; 80(5):1158-62. PubMed ID: 1381235
    [Abstract] [Full Text] [Related]

  • 10. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
    Longo GS, Gorlick R, Tong WP, Lin S, Steinherz P, Bertino JR.
    Oncol Res; 1997 Sep 01; 9(5):259-63. PubMed ID: 9306433
    [Abstract] [Full Text] [Related]

  • 11. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
    Synold TW, Relling MV, Boyett JM, Rivera GK, Sandlund JT, Mahmoud H, Crist WM, Pui CH, Evans WE.
    J Clin Invest; 1994 Nov 01; 94(5):1996-2001. PubMed ID: 7525652
    [Abstract] [Full Text] [Related]

  • 12. Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
    Masson E, Relling MV, Synold TW, Liu Q, Schuetz JD, Sandlund JT, Pui CH, Evans WE.
    J Clin Invest; 1996 Jan 01; 97(1):73-80. PubMed ID: 8550853
    [Abstract] [Full Text] [Related]

  • 13. Impaired polyglutamylation of methotrexate as a cause of resistance in CCRF-CEM cells after short-term, high-dose treatment with this drug.
    Pizzorno G, Mini E, Coronnello M, McGuire JJ, Moroson BA, Cashmore AR, Dreyer RN, Lin JT, Mazzei T, Periti P.
    Cancer Res; 1988 Apr 15; 48(8):2149-55. PubMed ID: 2450647
    [Abstract] [Full Text] [Related]

  • 14. Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia.
    Barredo JC, Synold TW, Laver J, Relling MV, Pui CH, Priest DG, Evans WE.
    Blood; 1994 Jul 15; 84(2):564-9. PubMed ID: 7517720
    [Abstract] [Full Text] [Related]

  • 15. Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia.
    Tulstrup M, Moriyama T, Jiang C, Grosjean M, Nersting J, Abrahamsson J, Grell K, Hjalgrim LL, Jónsson ÓG, Kanerva J, Lund B, Nielsen SN, Nielsen RL, Overgaard U, Quist-Paulsen P, Pruunsild K, Vaitkeviciene G, Wolthers BO, Zhang H, Gupta R, Yang JJ, Schmiegelow K.
    Blood; 2020 Sep 03; 136(10):1161-1168. PubMed ID: 32391884
    [Abstract] [Full Text] [Related]

  • 16. Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
    Rots MG, Pieters R, Kaspers GJ, van Zantwijk CH, Noordhuis P, Mauritz R, Veerman AJ, Jansen G, Peters GJ.
    Blood; 1999 Feb 01; 93(3):1067-74. PubMed ID: 9920857
    [Abstract] [Full Text] [Related]

  • 17. Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.
    Koizumi S, Curt GA, Fine RL, Griffin JD, Chabner BA.
    J Clin Invest; 1985 Mar 01; 75(3):1008-14. PubMed ID: 2579975
    [Abstract] [Full Text] [Related]

  • 18. Increased methotrexate polyglutamylation in acute megakaryocytic leukemia (M7) compared to other subtypes of acute myelocytic leukemia.
    Argiris A, Longo GS, Gorlick R, Tong W, Steinherz P, Bertino JR.
    Leukemia; 1997 Jun 01; 11(6):886-9. PubMed ID: 9177445
    [Abstract] [Full Text] [Related]

  • 19. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM, Vuchich MJ, Lauer SJ, Mahoney D, Carroll AJ, Shuster JJ, Esseltine DW, Payment C, Look AT, Akabutu J.
    Blood; 1992 Sep 01; 80(5):1316-23. PubMed ID: 1381244
    [Abstract] [Full Text] [Related]

  • 20. Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy.
    Nersting J, Nielsen SN, Grell K, Paerregaard M, Abrahamsson J, Lund B, Jonsson OG, Pruunsild K, Vaitkeviciene G, Kanerva J, Schmiegelow K, Nordic Society of Paediatric Haematology and Oncology (NOPHO).
    Cancer Chemother Pharmacol; 2019 Jan 01; 83(1):53-60. PubMed ID: 30324220
    [Abstract] [Full Text] [Related]

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