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Journal Abstract Search

326 related items for PubMed ID: 17237155

  • 21. Oseltamivir (Tamiflu) efflux transport at the blood-brain barrier via P-glycoprotein.
    Morimoto K, Nakakariya M, Shirasaka Y, Kakinuma C, Fujita T, Tamai I, Ogihara T.
    Drug Metab Dispos; 2008 Jan; 36(1):6-9. PubMed ID: 17940134
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  • 22. A Practical Perspective on the Evaluation of Small Molecule CNS Penetration in Drug Discovery.
    Huang L, Wells MC, Zhao Z.
    Drug Metab Lett; 2019 Jan; 13(2):78-94. PubMed ID: 30854983
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  • 23. P-glycoprotein restricts the penetration of oseltamivir across the blood-brain barrier.
    Ose A, Kusuhara H, Yamatsugu K, Kanai M, Shibasaki M, Fujita T, Yamamoto A, Sugiyama Y.
    Drug Metab Dispos; 2008 Feb; 36(2):427-34. PubMed ID: 18039806
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  • 24. Pharmacokinetics and pharmacodynamics of alfentanil in P-glycoprotein-competent and P-glycoprotein-deficient mice: P-glycoprotein efflux alters alfentanil brain disposition and antinociception.
    Kalvass JC, Olson ER, Pollack GM.
    Drug Metab Dispos; 2007 Mar; 35(3):455-9. PubMed ID: 17178769
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  • 25. Brain penetration of WEB 2086 (Apafant) and dantrolene in Mdr1a (P-glycoprotein) and Bcrp knockout rats.
    Fuchs H, Kishimoto W, Gansser D, Tanswell P, Ishiguro N.
    Drug Metab Dispos; 2014 Oct; 42(10):1761-5. PubMed ID: 25053619
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  • 26. Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of P-glycoprotein substrates in cynomolgus monkeys.
    Uchida Y, Wakayama K, Ohtsuki S, Chiba M, Ohe T, Ishii Y, Terasaki T.
    J Pharmacol Exp Ther; 2014 Sep; 350(3):578-88. PubMed ID: 24947467
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  • 27. Use of cassette dosing approach to examine the effects of P-glycoprotein on the brain and cerebrospinal fluid concentrations in wild-type and P-glycoprotein knockout rats.
    Liu X, Cheong J, Ding X, Deshmukh G.
    Drug Metab Dispos; 2014 Apr; 42(4):482-91. PubMed ID: 24398459
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  • 28. Utility of cerebrospinal fluid drug concentration as a surrogate for unbound brain concentration in nonhuman primates.
    Nagaya Y, Nozaki Y, Kobayashi K, Takenaka O, Nakatani Y, Kusano K, Yoshimura T, Kusuhara H.
    Drug Metab Pharmacokinet; 2014 Apr; 29(5):419-26. PubMed ID: 24806821
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  • 29. The role of P-glycoprotein in intestinal transport versus the BBB transport of tetraphenylphosphonium.
    Swed A, Eyal S, Madar I, Zohar-Kontante H, Weiss L, Hoffman A.
    Mol Pharm; 2009 Apr; 6(6):1883-90. PubMed ID: 19722701
    [Abstract] [Full Text] [Related]

  • 30. Species comparison of in vivo P-glycoprotein-mediated brain efflux using mdr1a-deficient rats and mice.
    Bundgaard C, Jensen CJ, Garmer M.
    Drug Metab Dispos; 2012 Mar; 40(3):461-6. PubMed ID: 22112383
    [Abstract] [Full Text] [Related]

  • 31. Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats using loperamide, paclitaxel, sulfasalazine, and carboxydichlorofluorescein pharmacokinetics.
    Zamek-Gliszczynski MJ, Bedwell DW, Bao JQ, Higgins JW.
    Drug Metab Dispos; 2012 Sep; 40(9):1825-33. PubMed ID: 22711747
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  • 38. P-glycoprotein and breast cancer resistance protein: two dominant transporters working together in limiting the brain penetration of topotecan.
    de Vries NA, Zhao J, Kroon E, Buckle T, Beijnen JH, van Tellingen O.
    Clin Cancer Res; 2007 Nov 01; 13(21):6440-9. PubMed ID: 17975156
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  • 40. Investigation of efflux transport of dehydroepiandrosterone sulfate and mitoxantrone at the mouse blood-brain barrier: a minor role of breast cancer resistance protein.
    Lee YJ, Kusuhara H, Jonker JW, Schinkel AH, Sugiyama Y.
    J Pharmacol Exp Ther; 2005 Jan 01; 312(1):44-52. PubMed ID: 15448171
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