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Journal Abstract Search

201 related items for PubMed ID: 17257837

  • 1. Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor.
    Suzuki T, Hisakawa S, Itoh Y, Maruyama S, Kurotaki M, Nakagawa H, Miyata N.
    Bioorg Med Chem Lett; 2007 Mar 15; 17(6):1558-61. PubMed ID: 17257837
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  • 3. Identification of KD5170: a novel mercaptoketone-based histone deacetylase inhibitor.
    Payne JE, Bonnefous C, Hassig CA, Symons KT, Guo X, Nguyen PM, Annable T, Wash PL, Hoffman TZ, Rao TS, Shiau AK, Malecha JW, Noble SA, Hager JH, Smith ND.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6093-6. PubMed ID: 18954983
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  • 4. Design and campaign synthesis of piperidine- and thiazole-based histone deacetylase inhibitors.
    Andrews DM, Stokes ES, Carr GR, Matusiak ZS, Roberts CA, Waring MJ, Brady MC, Chresta CM, East SJ.
    Bioorg Med Chem Lett; 2008 Apr 15; 18(8):2580-4. PubMed ID: 18378449
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  • 7. Design, synthesis, and evaluation of isoindolinone-hydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors.
    Lee S, Shinji C, Ogura K, Shimizu M, Maeda S, Sato M, Yoshida M, Hashimoto Y, Miyachi H.
    Bioorg Med Chem Lett; 2007 Sep 01; 17(17):4895-900. PubMed ID: 17588744
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  • 9. A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo.
    Jones P, Altamura S, De Francesco R, Paz OG, Kinzel O, Mesiti G, Monteagudo E, Pescatore G, Rowley M, Verdirame M, Steinkühler C.
    J Med Chem; 2008 Apr 24; 51(8):2350-3. PubMed ID: 18370373
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  • 13. Discovery of a potent class I selective ketone histone deacetylase inhibitor with antitumor activity in vivo and optimized pharmacokinetic properties.
    Kinzel O, Llauger-Bufi L, Pescatore G, Rowley M, Schultz-Fademrecht C, Monteagudo E, Fonsi M, Gonzalez Paz O, Fiore F, Steinkühler C, Jones P.
    J Med Chem; 2009 Jun 11; 52(11):3453-6. PubMed ID: 19441846
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  • 15. Synthesis and biological activity of prodrug inhibitors of the thioredoxin-thioredoxin reductase system.
    Wipf P, Lynch SM, Powis G, Birmingham A, Englund EE.
    Org Biomol Chem; 2005 Nov 07; 3(21):3880-2. PubMed ID: 16240002
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  • 16. Design, synthesis and preliminary biological evaluation of new hydroxamate histone deacetylase inhibitors as potential antileukemic agents.
    Guandalini L, Cellai C, Laurenzana A, Scapecchi S, Paoletti F, Romanelli MN.
    Bioorg Med Chem Lett; 2008 Sep 15; 18(18):5071-4. PubMed ID: 18723349
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