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Journal Abstract Search


570 related items for PubMed ID: 17261841

  • 1. Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade.
    Brown AL, Fernandez-Illescas SM, Liao Z, Goodman MB.
    J Gen Physiol; 2007 Feb; 129(2):161-73. PubMed ID: 17261841
    [Abstract] [Full Text] [Related]

  • 2. MEC-2 and MEC-6 in the Caenorhabditis elegans sensory mechanotransduction complex: auxiliary subunits that enable channel activity.
    Brown AL, Liao Z, Goodman MB.
    J Gen Physiol; 2008 Jun; 131(6):605-16. PubMed ID: 18504316
    [Abstract] [Full Text] [Related]

  • 3. The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel.
    Chelur DS, Ernstrom GG, Goodman MB, Yao CA, Chen L, O' Hagan R, Chalfie M.
    Nature; 2002 Dec 12; 420(6916):669-73. PubMed ID: 12478294
    [Abstract] [Full Text] [Related]

  • 4. Intersubunit interactions between mutant DEG/ENaCs induce synthetic neurotoxicity.
    Zhang W, Bianchi L, Lee WH, Wang Y, Israel S, Driscoll M.
    Cell Death Differ; 2008 Nov 12; 15(11):1794-803. PubMed ID: 18670436
    [Abstract] [Full Text] [Related]

  • 5. A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel.
    Gründer S, Firsov D, Chang SS, Jaeger NF, Gautschi I, Schild L, Lifton RP, Rossier BC.
    EMBO J; 1997 Mar 03; 16(5):899-907. PubMed ID: 9118951
    [Abstract] [Full Text] [Related]

  • 6. The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals.
    O'Hagan R, Chalfie M, Goodman MB.
    Nat Neurosci; 2005 Jan 03; 8(1):43-50. PubMed ID: 15580270
    [Abstract] [Full Text] [Related]

  • 7. MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation.
    Goodman MB, Ernstrom GG, Chelur DS, O'Hagan R, Yao CA, Chalfie M.
    Nature; 2002 Feb 28; 415(6875):1039-42. PubMed ID: 11875573
    [Abstract] [Full Text] [Related]

  • 8. Nanoscale organization of the MEC-4 DEG/ENaC sensory mechanotransduction channel in Caenorhabditis elegans touch receptor neurons.
    Cueva JG, Mulholland A, Goodman MB.
    J Neurosci; 2007 Dec 19; 27(51):14089-98. PubMed ID: 18094248
    [Abstract] [Full Text] [Related]

  • 9. Pore-lining residues of MEC-4 and MEC-10 channel subunits tune the Caenorhabditis elegans degenerin channel's response to shear stress.
    Shi S, Mutchler SM, Blobner BM, Kashlan OB, Kleyman TR.
    J Biol Chem; 2018 Jul 06; 293(27):10757-10766. PubMed ID: 29743244
    [Abstract] [Full Text] [Related]

  • 10. The DEG/ENaC protein MEC-10 regulates the transduction channel complex in Caenorhabditis elegans touch receptor neurons.
    Arnadóttir J, O'Hagan R, Chen Y, Goodman MB, Chalfie M.
    J Neurosci; 2011 Aug 31; 31(35):12695-704. PubMed ID: 21880930
    [Abstract] [Full Text] [Related]

  • 11. On the interaction between amiloride and its putative alpha-subunit epithelial Na+ channel binding site.
    Kashlan OB, Sheng S, Kleyman TR.
    J Biol Chem; 2005 Jul 15; 280(28):26206-15. PubMed ID: 15908426
    [Abstract] [Full Text] [Related]

  • 12. Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans.
    Chen Y, Bharill S, Isacoff EY, Chalfie M.
    Proc Natl Acad Sci U S A; 2015 Sep 15; 112(37):11690-5. PubMed ID: 26324944
    [Abstract] [Full Text] [Related]

  • 13. MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans.
    Chen Y, Bharill S, O'Hagan R, Isacoff EY, Chalfie M.
    G3 (Bethesda); 2016 Apr 07; 6(4):1121-30. PubMed ID: 27172609
    [Abstract] [Full Text] [Related]

  • 14. Influence of voltage and extracellular Na(+) on amiloride block and transport kinetics of rat epithelial Na(+) channel expressed in Xenopus oocytes.
    Segal A, Awayda MS, Eggermont J, Van Driessche W, Weber WM.
    Pflugers Arch; 2002 Mar 07; 443(5-6):882-91. PubMed ID: 11889589
    [Abstract] [Full Text] [Related]

  • 15. External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probability.
    Sheng S, Perry CJ, Kleyman TR.
    J Biol Chem; 2002 Dec 20; 277(51):50098-111. PubMed ID: 12397059
    [Abstract] [Full Text] [Related]

  • 16. Temperature-sensitive mutant of the Caenorhabditis elegans neurotoxic MEC-4(d) DEG/ENaC channel identifies a site required for trafficking or surface maintenance.
    Royal DC, Bianchi L, Royal MA, Lizzio M, Mukherjee G, Nunez YO, Driscoll M.
    J Biol Chem; 2005 Dec 23; 280(51):41976-86. PubMed ID: 16239217
    [Abstract] [Full Text] [Related]

  • 17. Mutations in the pore region modify epithelial sodium channel gating by shear stress.
    Carattino MD, Sheng S, Kleyman TR.
    J Biol Chem; 2005 Feb 11; 280(6):4393-401. PubMed ID: 15569663
    [Abstract] [Full Text] [Related]

  • 18. A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans.
    Hong K, Driscoll M.
    Nature; 1994 Feb 03; 367(6462):470-3. PubMed ID: 8107806
    [Abstract] [Full Text] [Related]

  • 19. Ca2+ permeability and Na+ conductance in cellular toxicity caused by hyperactive DEG/ENaC channels.
    Matthewman C, Miller-Fleming TW, Miller DM, Bianchi L.
    Am J Physiol Cell Physiol; 2016 Dec 01; 311(6):C920-C930. PubMed ID: 27760755
    [Abstract] [Full Text] [Related]

  • 20. Gamma subunit second transmembrane domain contributes to epithelial sodium channel gating and amiloride block.
    Shi S, Kleyman TR.
    Am J Physiol Renal Physiol; 2013 Dec 01; 305(11):F1585-92. PubMed ID: 24107424
    [Abstract] [Full Text] [Related]


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