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Journal Abstract Search

260 related items for PubMed ID: 17266201

  • 1. Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands.
    Salama I, Hocke C, Utz W, Prante O, Boeckler F, Hübner H, Kuwert T, Gmeiner P.
    J Med Chem; 2007 Feb 08; 50(3):489-500. PubMed ID: 17266201
    [Abstract] [Full Text] [Related]

  • 2. Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor.
    Grundt P, Carlson EE, Cao J, Bennett CJ, McElveen E, Taylor M, Luedtke RR, Newman AH.
    J Med Chem; 2005 Feb 10; 48(3):839-48. PubMed ID: 15689168
    [Abstract] [Full Text] [Related]

  • 3. 18F-Labeled FAUC 346 and BP 897 derivatives as subtype-selective potential PET radioligands for the dopamine D3 receptor.
    Hocke C, Prante O, Salama I, Hübner H, Löber S, Kuwert T, Gmeiner P.
    ChemMedChem; 2008 May 10; 3(5):788-93. PubMed ID: 18306190
    [Abstract] [Full Text] [Related]

  • 4. CoMFA and CoMSIA investigations of dopamine D3 receptor ligands leading to the prediction, synthesis, and evaluation of rigidized FAUC 365 analogues.
    Salama I, Schlotter K, Utz W, Hübner H, Gmeiner P, Boeckler F.
    Bioorg Med Chem; 2006 Sep 01; 14(17):5898-912. PubMed ID: 16750374
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents.
    Hocke C, Prante O, Löber S, Hübner H, Gmeiner P, Kuwert T.
    Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4819-23. PubMed ID: 16139501
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands with optimal lipophilicity for brain imaging of the dopamine D3 receptor. Part II.
    Leopoldo M, Lacivita E, De Giorgio P, Contino M, Berardi F, Perrone R.
    Bioorg Med Chem; 2009 Jan 15; 17(2):758-66. PubMed ID: 19081257
    [Abstract] [Full Text] [Related]

  • 7. Dopamine D2, D3, and D4 selective phenylpiperazines as molecular probes to explore the origins of subtype specific receptor binding.
    Ehrlich K, Götz A, Bollinger S, Tschammer N, Bettinetti L, Härterich S, Hübner H, Lanig H, Gmeiner P.
    J Med Chem; 2009 Aug 13; 52(15):4923-35. PubMed ID: 19606869
    [Abstract] [Full Text] [Related]

  • 8. N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand.
    Perrone R, Berardi F, Colabufo NA, Leopoldo M, Tortorella V.
    J Med Chem; 1998 Nov 19; 41(24):4903-9. PubMed ID: 9822559
    [Abstract] [Full Text] [Related]

  • 9. Evaluation of 18F-labeled benzodioxine piperazine-based dopamine D4 receptor ligands: lipophilicity as a determinate of nonspecific binding.
    Kügler F, Sihver W, Ermert J, Hübner H, Gmeiner P, Prante O, Coenen HH.
    J Med Chem; 2011 Dec 22; 54(24):8343-52. PubMed ID: 22039961
    [Abstract] [Full Text] [Related]

  • 10. Phenylpiperazinylmethylheterocycle derivatives: synthesis and dopamine receptor binding profiles.
    Abadi AH.
    Arch Pharm (Weinheim); 2004 Jul 22; 337(7):383-90. PubMed ID: 15237388
    [Abstract] [Full Text] [Related]

  • 11. CoMFA and CoMSIA investigations revealing novel insights into the binding modes of dopamine D3 receptor agonists.
    Boeckler F, Ohnmacht U, Lehmann T, Utz W, Hübner H, Gmeiner P.
    J Med Chem; 2005 Apr 07; 48(7):2493-508. PubMed ID: 15801839
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, biological evaluation and radiolabelling by 18F-fluoroarylation of a dopamine D3-selective ligand as prospective imaging probe for PET.
    Höfling SB, Maschauer S, Hübner H, Gmeiner P, Wester HJ, Prante O, Heinrich MR.
    Bioorg Med Chem Lett; 2010 Dec 01; 20(23):6933-7. PubMed ID: 21030255
    [Abstract] [Full Text] [Related]

  • 13. Bivalent molecular probes for dopamine D2-like receptors.
    Huber D, Löber S, Hübner H, Gmeiner P.
    Bioorg Med Chem; 2012 Jan 01; 20(1):455-66. PubMed ID: 22100258
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands for visualization of brain dopamine D3 receptors.
    Leopoldo M, Lacivita E, De Giorgio P, Colabufo NA, Niso M, Berardi F, Perrone R.
    J Med Chem; 2006 Jan 12; 49(1):358-65. PubMed ID: 16392820
    [Abstract] [Full Text] [Related]

  • 15. N-(omega-(4-(2-methoxyphenyl)piperazin-1-yl)alkyl)carboxamides as dopamine D2 and D3 receptor ligands.
    Hackling A, Ghosh R, Perachon S, Mann A, Höltje HD, Wermuth CG, Schwartz JC, Sippl W, Sokoloff P, Stark H.
    J Med Chem; 2003 Aug 28; 46(18):3883-99. PubMed ID: 12930150
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and structure-activity relationship studies of hexahydropyrazinoquinolines as a novel class of potent and selective dopamine receptor 3 (D3) ligands.
    Ji M, Chen J, Ding K, Wu X, Varady J, Levant B, Wang S.
    Bioorg Med Chem Lett; 2005 Mar 15; 15(6):1701-5. PubMed ID: 15745825
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype.
    Hocke C, Prante O, Löber S, Hübner H, Gmeiner P, Kuwert T.
    Bioorg Med Chem Lett; 2004 Aug 02; 14(15):3963-6. PubMed ID: 15225707
    [Abstract] [Full Text] [Related]

  • 18. Development of novel 1,2,3,4-tetrahydroisoquinoline derivatives and closely related compounds as potent and selective dopamine D3 receptor ligands.
    Mach UR, Hackling AE, Perachon S, Ferry S, Wermuth CG, Schwartz JC, Sokoloff P, Stark H.
    Chembiochem; 2004 Apr 02; 5(4):508-18. PubMed ID: 15185375
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands.
    Ortega R, Raviña E, Masaguer CF, Areias F, Brea J, Loza MI, López L, Selent J, Pastor M, Sanz F.
    Bioorg Med Chem Lett; 2009 Mar 15; 19(6):1773-8. PubMed ID: 19217777
    [Abstract] [Full Text] [Related]

  • 20. Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies.
    Bennacef I, Salinas CA, Bonasera TA, Gunn RN, Audrain H, Jakobsen S, Nabulsi N, Weinzimmer D, Carson RE, Huang Y, Holmes I, Micheli F, Heidbreder C, Gentile G, Rossi T, Laruelle M.
    Bioorg Med Chem Lett; 2009 Sep 01; 19(17):5056-9. PubMed ID: 19635669
    [Abstract] [Full Text] [Related]

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