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Journal Abstract Search

226 related items for PubMed ID: 17277109

  • 1. Changes in the role of the CD45 protein tyrosine phosphatase in regulating Lck tyrosine phosphorylation during thymic development.
    Falahati R, Leitenberg D.
    J Immunol; 2007 Feb 15; 178(4):2056-64. PubMed ID: 17277109
    [Abstract] [Full Text] [Related]

  • 2. CD45 down-regulates Lck-mediated CD44 signaling and modulates actin rearrangement in T cells.
    Wong NK, Lai JC, Birkenhead D, Shaw AS, Johnson P.
    J Immunol; 2008 Nov 15; 181(10):7033-43. PubMed ID: 18981123
    [Abstract] [Full Text] [Related]

  • 3. Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions.
    Kästle M, Merten C, Hartig R, Kaehne T, Liaunardy-Jopeace A, Woessner NM, Schamel WW, James J, Minguet S, Simeoni L, Schraven B.
    Cell Commun Signal; 2020 Nov 23; 18(1):183. PubMed ID: 33225946
    [Abstract] [Full Text] [Related]

  • 4. The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: restoration of pre-TCR function by active p56(lck).
    Pingel S, Baker M, Turner M, Holmes N, Alexander DR.
    Eur J Immunol; 1999 Aug 23; 29(8):2376-84. PubMed ID: 10458749
    [Abstract] [Full Text] [Related]

  • 5. Cutting edge: the CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes.
    D'Oro U, Ashwell JD.
    J Immunol; 1999 Feb 15; 162(4):1879-83. PubMed ID: 9973453
    [Abstract] [Full Text] [Related]

  • 6. CD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytes.
    Ng DH, Jabali MD, Maiti A, Borodchak P, Harder KW, Brocker T, Malissen B, Jirik FR, Johnson P.
    Biochem J; 1997 Nov 01; 327 ( Pt 3)(Pt 3):867-76. PubMed ID: 9581568
    [Abstract] [Full Text] [Related]

  • 7. ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
    Ashe JM, Wiest DL, Abe R, Singer A.
    J Exp Med; 1999 Apr 05; 189(7):1163-8. PubMed ID: 10190908
    [Abstract] [Full Text] [Related]

  • 8. Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.
    Stephen TL, Wilson BS, Laufer TM.
    Proc Natl Acad Sci U S A; 2012 May 08; 109(19):7415-20. PubMed ID: 22529380
    [Abstract] [Full Text] [Related]

  • 9. Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule.
    Tsujikawa K, Ichijo T, Moriyama K, Tadotsu N, Sakamoto K, Sakane N, Fukada S, Furukawa T, Saito H, Yamamoto H.
    Mol Cancer Res; 2002 Dec 08; 1(2):155-63. PubMed ID: 12496362
    [Abstract] [Full Text] [Related]

  • 10. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.
    Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A.
    J Exp Med; 1993 Nov 01; 178(5):1701-12. PubMed ID: 8228817
    [Abstract] [Full Text] [Related]

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  • 12. The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.
    McNeill L, Salmond RJ, Cooper JC, Carret CK, Cassady-Cain RL, Roche-Molina M, Tandon P, Holmes N, Alexander DR.
    Immunity; 2007 Sep 01; 27(3):425-37. PubMed ID: 17719247
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  • 15. Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development.
    Falahati R, Leitenberg D.
    J Immunol; 2008 Nov 01; 181(9):6082-91. PubMed ID: 18941197
    [Abstract] [Full Text] [Related]

  • 16. Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70.
    Stone JD, Conroy LA, Byth KF, Hederer RA, Howlett S, Takemoto Y, Holmes N, Alexander DR.
    J Immunol; 1997 Jun 15; 158(12):5773-82. PubMed ID: 9190928
    [Abstract] [Full Text] [Related]

  • 17. Mutational analysis of Lck in CD45-negative T cells: dominant role of tyrosine 394 phosphorylation in kinase activity.
    D'Oro U, Sakaguchi K, Appella E, Ashwell JD.
    Mol Cell Biol; 1996 Sep 15; 16(9):4996-5003. PubMed ID: 8756658
    [Abstract] [Full Text] [Related]

  • 18. Expression of CD45 lacking the catalytic protein tyrosine phosphatase domain modulates Lck phosphorylation and T cell activation.
    Wang Y, Johnson P.
    J Biol Chem; 2005 Apr 08; 280(14):14318-24. PubMed ID: 15687496
    [Abstract] [Full Text] [Related]

  • 19. CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.
    Sieh M, Bolen JB, Weiss A.
    EMBO J; 1993 Jan 08; 12(1):315-21. PubMed ID: 8428589
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