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Journal Abstract Search

261 related items for PubMed ID: 17277159

  • 1. Simvastatin potentiates TNF-alpha-induced apoptosis through the down-regulation of NF-kappaB-dependent antiapoptotic gene products: role of IkappaBalpha kinase and TGF-beta-activated kinase-1.
    Ahn KS, Sethi G, Aggarwal BB.
    J Immunol; 2007 Feb 15; 178(4):2507-16. PubMed ID: 17277159
    [Abstract] [Full Text] [Related]

  • 2. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
    Ichikawa H, Takada Y, Murakami A, Aggarwal BB.
    J Immunol; 2005 Jun 01; 174(11):7383-92. PubMed ID: 15905586
    [Abstract] [Full Text] [Related]

  • 3. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB.
    Mol Pharmacol; 2006 Jan 01; 69(1):195-206. PubMed ID: 16219905
    [Abstract] [Full Text] [Related]

  • 4. Simvastatin in combination with bergamottin potentiates TNF-induced apoptosis through modulation of NF-κB signalling pathway in human chronic myelogenous leukaemia.
    Kim SM, Lee EJ, Lee JH, Yang WM, Nam D, Lee JH, Lee SG, Um JY, Shim BS, Ahn KS.
    Pharm Biol; 2016 Oct 01; 54(10):2050-60. PubMed ID: 26911804
    [Abstract] [Full Text] [Related]

  • 5. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B, Pandey MK, Aggarwal BB.
    Mol Pharmacol; 2007 Jun 01; 71(6):1703-14. PubMed ID: 17387141
    [Abstract] [Full Text] [Related]

  • 6. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB.
    Cancer Res; 2005 Oct 15; 65(20):9555-65. PubMed ID: 16230421
    [Abstract] [Full Text] [Related]

  • 7. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
    Takada Y, Kobayashi Y, Aggarwal BB.
    J Biol Chem; 2005 Apr 29; 280(17):17203-12. PubMed ID: 15710601
    [Abstract] [Full Text] [Related]

  • 8. Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.
    Ahn KS, Sethi G, Krishnan K, Aggarwal BB.
    J Biol Chem; 2007 Jan 05; 282(1):809-20. PubMed ID: 17114179
    [Abstract] [Full Text] [Related]

  • 9. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
    Shukla S, Gupta S.
    Clin Cancer Res; 2004 May 01; 10(9):3169-78. PubMed ID: 15131058
    [Abstract] [Full Text] [Related]

  • 10. Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.
    Takada Y, Murakami A, Aggarwal BB.
    Oncogene; 2005 Oct 20; 24(46):6957-69. PubMed ID: 16007145
    [Abstract] [Full Text] [Related]

  • 11. Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation.
    Sethi G, Ahn KS, Pandey MK, Aggarwal BB.
    Blood; 2007 Apr 01; 109(7):2727-35. PubMed ID: 17110449
    [Abstract] [Full Text] [Related]

  • 12. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G, Ahn KS, Sung B, Aggarwal BB.
    Mol Cancer Ther; 2008 Jun 01; 7(6):1604-14. PubMed ID: 18566231
    [Abstract] [Full Text] [Related]

  • 13. Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression.
    Takada Y, Ichikawa H, Badmaev V, Aggarwal BB.
    J Immunol; 2006 Mar 01; 176(5):3127-40. PubMed ID: 16493072
    [Abstract] [Full Text] [Related]

  • 14. Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
    Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.
    Oncogene; 2007 Feb 22; 26(8):1201-12. PubMed ID: 16924232
    [Abstract] [Full Text] [Related]

  • 15. 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
    Yadav VR, Prasad S, Gupta SC, Sung B, Phatak SS, Zhang S, Aggarwal BB.
    J Biol Chem; 2012 Jan 02; 287(1):245-256. PubMed ID: 22065587
    [Abstract] [Full Text] [Related]

  • 16. Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1.
    Shishodia S, Majumdar S, Banerjee S, Aggarwal BB.
    Cancer Res; 2003 Aug 01; 63(15):4375-83. PubMed ID: 12907607
    [Abstract] [Full Text] [Related]

  • 17. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
    Pandey MK, Sung B, Kunnumakkara AB, Sethi G, Chaturvedi MM, Aggarwal BB.
    Cancer Res; 2008 Jul 01; 68(13):5370-9. PubMed ID: 18593939
    [Abstract] [Full Text] [Related]

  • 18. Indole-3-carbinol suppresses NF-kappaB and IkappaBalpha kinase activation, causing inhibition of expression of NF-kappaB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells.
    Takada Y, Andreeff M, Aggarwal BB.
    Blood; 2005 Jul 15; 106(2):641-9. PubMed ID: 15811958
    [Abstract] [Full Text] [Related]

  • 19. Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation.
    Takada Y, Gillenwater A, Ichikawa H, Aggarwal BB.
    J Biol Chem; 2006 Mar 03; 281(9):5612-22. PubMed ID: 16377638
    [Abstract] [Full Text] [Related]

  • 20. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
    Kunnumakkara AB, Ichikawa H, Anand P, Mohankumar CJ, Hema PS, Nair MS, Aggarwal BB.
    Mol Cancer Ther; 2008 Oct 03; 7(10):3306-17. PubMed ID: 18852134
    [Abstract] [Full Text] [Related]

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