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709 related items for PubMed ID: 17277231

  • 1. Bax and Bak genes are essential for maximum apoptotic response by curcumin, a polyphenolic compound and cancer chemopreventive agent derived from turmeric, Curcuma longa.
    Shankar S, Srivastava RK.
    Carcinogenesis; 2007 Jun; 28(6):1277-86. PubMed ID: 17277231
    [Abstract] [Full Text] [Related]

  • 2. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 3. Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.
    Rashmi R, Kumar S, Karunagaran D.
    Carcinogenesis; 2005 Apr 01; 26(4):713-23. PubMed ID: 15661804
    [Abstract] [Full Text] [Related]

  • 4. Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer.
    Shankar S, Srivastava RK.
    Int J Oncol; 2007 Apr 01; 30(4):905-18. PubMed ID: 17332930
    [Abstract] [Full Text] [Related]

  • 5. Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.
    Choi S, Singh SV.
    Cancer Res; 2005 Mar 01; 65(5):2035-43. PubMed ID: 15753404
    [Abstract] [Full Text] [Related]

  • 6. Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L).
    Lindenboim L, Blacher E, Borner C, Stein R.
    Cell Death Differ; 2010 Feb 01; 17(2):346-59. PubMed ID: 19816507
    [Abstract] [Full Text] [Related]

  • 7. Triggering of apoptosis by Puma is determined by the threshold set by prosurvival Bcl-2 family proteins.
    Callus BA, Moujallad DM, Silke J, Gerl R, Jabbour AM, Ekert PG, Vaux DL.
    J Mol Biol; 2008 Dec 12; 384(2):313-23. PubMed ID: 18835564
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of the ER Ca2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis.
    Janssen K, Horn S, Niemann MT, Daniel PT, Schulze-Osthoff K, Fischer U.
    J Cell Sci; 2009 Dec 15; 122(Pt 24):4481-91. PubMed ID: 19920074
    [Abstract] [Full Text] [Related]

  • 9. Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax.
    Xiao D, Zeng Y, Choi S, Lew KL, Nelson JB, Singh SV.
    Clin Cancer Res; 2005 Apr 01; 11(7):2670-9. PubMed ID: 15814648
    [Abstract] [Full Text] [Related]

  • 10. Bak but not Bax is essential for Bcl-xS-induced apoptosis.
    Lindenboim L, Kringel S, Braun T, Borner C, Stein R.
    Cell Death Differ; 2005 Jul 01; 12(7):713-23. PubMed ID: 15861188
    [Abstract] [Full Text] [Related]

  • 11. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.
    Boya P, Gonzalez-Polo RA, Poncet D, Andreau K, Vieira HL, Roumier T, Perfettini JL, Kroemer G.
    Oncogene; 2003 Jun 19; 22(25):3927-36. PubMed ID: 12813466
    [Abstract] [Full Text] [Related]

  • 12. Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.
    Hikita H, Takehara T, Kodama T, Shimizu S, Shigekawa M, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Shimizu S, Tsujimoto Y, Hayashi N.
    Hepatology; 2011 Jul 19; 54(1):240-51. PubMed ID: 21425311
    [Abstract] [Full Text] [Related]

  • 13. The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family.
    Boya P, Morales MC, Gonzalez-Polo RA, Andreau K, Gourdier I, Perfettini JL, Larochette N, Deniaud A, Baran-Marszak F, Fagard R, Feuillard J, Asumendi A, Raphael M, Pau B, Brenner C, Kroemer G.
    Oncogene; 2003 Sep 18; 22(40):6220-30. PubMed ID: 13679861
    [Abstract] [Full Text] [Related]

  • 14. Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells.
    Kim MJ, Lee KH, Lee SJ.
    FEBS J; 2008 May 18; 275(9):2096-108. PubMed ID: 18373696
    [Abstract] [Full Text] [Related]

  • 15. Curcumin activated both receptor-mediated and mitochondria-mediated proteolytic pathways for apoptosis in human glioblastoma T98G cells.
    Karmakar S, Banik NL, Patel SJ, Ray SK.
    Neurosci Lett; 2006 Oct 16; 407(1):53-8. PubMed ID: 16949208
    [Abstract] [Full Text] [Related]

  • 16. Acquired resistance to rituximab is associated with chemotherapy resistance resulting from decreased Bax and Bak expression.
    Olejniczak SH, Hernandez-Ilizaliturri FJ, Clements JL, Czuczman MS.
    Clin Cancer Res; 2008 Mar 01; 14(5):1550-60. PubMed ID: 18316580
    [Abstract] [Full Text] [Related]

  • 17. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.
    Zi X, Simoneau AR.
    Cancer Res; 2005 Apr 15; 65(8):3479-86. PubMed ID: 15833884
    [Abstract] [Full Text] [Related]

  • 18. Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak.
    Neise D, Graupner V, Gillissen BF, Daniel PT, Schulze-Osthoff K, Jänicke RU, Essmann F.
    Oncogene; 2008 Feb 28; 27(10):1387-96. PubMed ID: 17724463
    [Abstract] [Full Text] [Related]

  • 19. Critical role for mitochondrial oxidative phosphorylation in the activation of tumor suppressors Bax and Bak.
    Tomiyama A, Serizawa S, Tachibana K, Sakurada K, Samejima H, Kuchino Y, Kitanaka C.
    J Natl Cancer Inst; 2006 Oct 18; 98(20):1462-73. PubMed ID: 17047195
    [Abstract] [Full Text] [Related]

  • 20. Induction apoptosis of luteolin in human hepatoma HepG2 cells involving mitochondria translocation of Bax/Bak and activation of JNK.
    Lee HJ, Wang CJ, Kuo HC, Chou FP, Jean LF, Tseng TH.
    Toxicol Appl Pharmacol; 2005 Mar 01; 203(2):124-31. PubMed ID: 15710173
    [Abstract] [Full Text] [Related]


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